HPV triage data
May 2001
Cunningham Pathology, Birmingham, Ala. 91 percent biopsy confirmation
Forty-nine total cases (preliminary diagnosis ASCUS) were sent for HPV triage. All cases were referred to cytopathologist (Dr. Lozano) before being sent for molecular testing. The HPV data and re-review of the cytology were then used to change the diagnosis as follows:
18 changed to benign cellular changes/within normal limits
- 14 with no followup data
- 3 with normal/inflammatory followup data
- 1 HPV
4 called ASCUS favor LSIL (with no high-risk HPV)
- 3 with no followup data
- 1 with normal/inflammatory followup data
15 called LSIL (mild dysplasia/HPV), high-risk HPV present
- 5 with no followup data
- 9 with mild dysplasia/HPV
- 1 with normal/inflammatory followup data
12 called HSIL (moderate, severe, CIS) (100 percent biopsy confirmation)
- 3 with no followup data
- 9 CIN II-III
The cases with no followup are recent cases. The benign-cellular-changes cases may not ever be biopsied, so they might have to rely on followup cytology.
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