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| Name of instrument/First year sold/Where designed | LIAISON/1997/Germany |
| Country where manufactured/Where reagents manufactured | Germany/U.S., Italy |
| No. of units in clinical use in U.S./Outside U.S. | >500/>4,000 |
| Operational type/Model type/Sample handling system | batch, continuous random access/benchtop/rack |
| Dimensions in inches (H × W × D)/Instrument footprint in sq. feet | 45 × 96 × 34/10 |
| Tests available on instrument in U.S. | 25 hydroxyvitamin D total, intact PTH, EBV IgM, EBNA IgG, VCA IgG, EA IgG, toxo IgG, toxo IgM, CMV IgG, CMV IgM, treponema IgG/IgM, VZV IgG, hGH, Borrelia burgdorferi, HAV IgM, HAV total antibodies, rubella IgG, HSV-1 type specific IgG, HSV-2 type specific IgG, insulin, measles IgG, mumps IgG |
| Tests not available in U.S. but submitted for clearance | — |
| Tests not available in U.S. but available in other countries | avidity, HSV I/II IgM, HSV I/II IgG, HCG, β-2-microglobulin, prolactin, LH, FSH, S-100, AFP, HCG, ferritin, TSH, FT3, FT4, T3, T4, anti-TG, TG, anti-TPO, rubella IgM, many others |
| Tests in development | — |
| Tests not available on other manufacturers’ analyzers | Borrelia burgdorferi |
| Fully automated microplate system | no |
| Number of each analyte performed in separate disposable unit | — |
| Number of wells in microplate | — |
| Methods supported/Separation methods | chemiluminescence/magnetic particle |
| Number of different measured assays onboard simultaneously | 15 |
| Number of different assays programmed, calibrated at once | 15 |
| Number of user-definable (open) channels | 0 |
| Number of different analytes for which system accommodates reagent containers onboard at once/Tests per container set | 15/100 |
| Shortest/Median onboard reagent stability/Refrigerated onboard | 7/28 days/yes (12°C) |
| Multiple reagent configurations supported | no |
| Reagent container placed directly on system for use | yes |
| Reagents bar coded/Information in bar code | yes/all lot information |
| Same capabilities when 3rd-party reagents used/Susceptibility to carryover | no/no |
| Walkaway capacity in minutes/Specimens/Tests-assays | 360/144/1,500 |
| System is open (home-brew methods can be used)/Liquid or dry system | no/liquid |
| Uses disposable cuvettes/Maximum number stored | yes/720 |
| Uses washable cuvettes/Replacement frequency | no/— |
| Minimum specimen volume required | assay dependent |
| Minimum sample vol. aspirated precisely at once/Minimum dead volume | 5 µL/150 µL |
| Supplied with UPS (backup power)/Requires floor drain | yes/no |
| Requires dedicated water system/Water consumption | no/— |
| Noise generated | — |
| Has dedicated pediatric sample cup/Dead volume | no/75 µL |
| Primary tube sampling/Tube sizes/Pierces caps on primary tubes | yes/—/no |
| Sample bar-code reading capability/Autodiscrimination | yes (2 of 5 interleaved, Codabar, codes 39 and 128)/yes |
| Bar-code placement per CLSI standard Auto2A | yes |
| Onboard test auto inventory (determines volume in container) | yes |
| Measures No. of tests remaining/Short sample detection | yes/yes |
| Auto detection of adequate reagent or specimen | yes |
| Clot detection/Reflex testing capability | yes/yes |
| Hemolysis detection-quantitation/Turbidity detection-quantitation | no/no |
| Dilution of patient samples onboard/Automatic rerun capability | yes/yes |
| Sample volume can be increased to rerun out-of-linear range high results/ Increased to rerun out-of-linear range low results | no/no |
| Time between initial result and reaspiration of sample for rerun | 2 minutes |
| Autocalibration or autocalibration alert | no |
| Number of calibrators required for each analyte | 2 |
| Calibrants can be stored onboard/Average calibration frequency | yes/28 days |
| Multipoint calib. supported/Multiple calibs. stored for same assay | yes/no |
| How often QC required | 24 hours |
| Onboard real-time QC/Support multiple QC lot Nos. per analyte | no/yes |
| Automatic shutdown/Startup is programmable/Startup time | no/no/15 minutes |
| Stat time to completion of β-hCG test | — |
| Time delay from ordering stat test to aspiration of sample | 1 minutes |
| Throughput per hour for three analytes on each specimen, in No. of specimens/No. of tests (cycle time) | — |
| Can auto transfer QC results to LIS/Onboard capability to review QC | yes/yes |
| Data-management capability/Instrument vendor supplies LIS interface | yes/yes (additional) |
| LIS interfaces up and running in active user sites | Cerner, Soft, others |
| LIS interface operates simultaneously w/running assays | yes |
| Bidirectional interface capability | yes (host query) |
| Interface available (or will be) to auto specimen handling system | no |
| Modem servicing/Can diagnose own malfunctions/ Determine malfunctioning component | no/no/no |
| Can order (via modem) malfunctioning part(s) w/o operator | no |
| On-site response time of service engineer | 24 hours |
| Mean time between failures/To repair failures | — |
| Avg. time to complete maintenance by lab personnel | daily: 10 minutes; weekly: 20 minutes; monthly: 30 minutes |
| Onboard maintenance records/Maintenance training demo module | no/no |
| List price/Targeted bed size or daily volume | $176,000 (includes first year of service)/all bed sizes, all volumes |
| Annual service contract cost (24 hours/7 days) | — |
| Training provided w/purchase/Advanced operator training | 3 days on site/yes |
| Distinguishing features (supplied by vendor) | fully automated benchtop analyzer with high throughput; unique menu; up to 15 assays onboard with ready-to-use, reagent-integral, random-access, batch and stat operation |
| Tabulation does not represent an endorsement by the College of American Pathologists. |
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