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DiaSorin, LIAISON (Immunoassay 2014)

DiaSorin, LIAISON (Immunoassay 2014)

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Contact Information

DiaSorin Inc.
Brian Lauber
1951 Northwestern Ave.
Stillwater, MN 55082

Name of instrument/First year sold/Where designed LIAISON/1997/Germany
Country where manufactured/Where reagents manufactured Germany/U.S., Italy
Number of units in clinical use in U.S./Outside U.S. >360/>4,100
Operational type/Model type/Sample handling system batch, continuous random access/benchtop/rack
Dimensions in inches (H × W × D)/Instrument footprint in sq. feet 45 × 96 × 34/10
Tests available on instrument in U.S. 25 hydroxyvitamin D total, intact PTH, EBV IgM, EBNA IgG, VCA IgG, EA IgG, toxo IgG, toxo IgM, CMV IgG, CMV IgM, treponema IgG/IgM, VZV IgG, hGH, Borrelia burgdorferi, HAV IgM, HAV total antibodies, rubella IgG, HSV-1 type specific IgG, HSV-2 type specific IgG, insulin, measles IgG, mumps IgG, rubella IgM, IGF-1, testosterone, estradiol, FT4, direct renin, aldosterone, LH, FSH, C-peptid, FT3, prolactin, progesterone
Tests not available in U.S. but submitted for clearance
Tests not available in U.S. but available in other countries avidity, HSV I/II IgM, HSV I/II IgG, β-2-microglobulin, S-100, AFP, ferritin, T3, T4, anti-TG, TG
Tests in development procalcitonin
Tests not available on other manufacturers’ analyzers
Fully automated microplate system no
Number of each analyte performed in separate disposable unit
Number of wells in microplate
Methods supported/Separation methods chemiluminescence/magnetic particle
Number of different measured assays onboard simultaneously 15
Number of different assays programmed, calibrated at once 15
Number of user-definable (open) channels 0
Number of different analytes for which system accommodates reagent containers onboard at once/Tests per container set 15/100
Shortest/Median onboard reagent stability/Refrigerated onboard 7/28 days/yes (12°C)
Multiple reagent configurations supported no
Reagent container placed directly on system for use yes
Reagents bar coded/Information in bar code yes/all lot information
Same capabilities when 3rd-party reagents used/Susceptibility to carryover no/no
Walkaway capacity in minutes/Specimens/Tests-assays 360/144/1,500
System is open (home-brew methods can be used)/Liquid or dry system no/liquid
Uses disposable cuvettes/Maximum number stored yes/720
Uses washable cuvettes/Replacement frequency no/—
Minimum specimen volume required assay dependent
Minimum sample volume aspirated precisely at once/Minimum dead volume 5 µL/150 µL
Supplied with UPS (backup power)/Requires floor drain yes/no
Requires dedicated water system/Water consumption no/—
Noise generated
Has dedicated pediatric sample cup/Dead volume no/75 µL
Primary tube sampling/Tube sizes/Pierces caps on primary tubes yes/—/no
Sample bar-code reading capability/Autodiscrimination yes (2 of 5 interleaved, Codabar, codes 39 and 128)/yes
Bar-code placement per CLSI standard Auto2A yes
Onboard test auto inventory (determines volume in container) yes
Measures number of tests remaining/Short sample detection yes/yes
Auto detection of adequate reagent or specimen yes
Clot detection/Reflex testing capability yes/yes
Hemolysis detection-quantitation/Turbidity detection-quantitation no/no
Dilution of patient samples onboard/Automatic rerun capability yes/yes
Sample volume can be increased to rerun out-of-linear range high results/ Increased to rerun out-of-linear range low results no/no
Time between initial result and reaspiration of sample for rerun 2 minutes
Autocalibration or autocalibration alert no
Number of calibrators required for each analyte 2
Calibrants can be stored onboard/Average calibration frequency yes/28 days
Multipoint calib. supported/Multiple calibs. stored for same assay yes/no
How often QC required 24 hours
Onboard real-time QC/Support multiple QC lot Nos. per analyte no/yes
Automatic shutdown/Startup is programmable/Startup time no/no/15 minutes
Stat time to completion of β-hCG test
Time delay from ordering stat test to aspiration of sample 2 minutes
Throughput per hour for three analytes on each specimen, in number of specimens/Number of tests (cycle time)
Can auto transfer QC results to LIS/Onboard capability to review QC yes/yes
Data-management capability/Instrument vendor supplies LIS interface yes/yes (additional cost)
LIS interfaces up and running in active user sites Cerner, Soft, others
LIS interface operates simultaneously w/running assays yes
Bidirectional interface capability yes (host query)
Interface available (or will be) to auto specimen handling system no
Modem servicing/Can diagnose own malfunctions/ Determine malfunctioning component no/no/no
Can order (via modem) malfunctioning part(s) without operator no
On-site response time of service engineer 24 hours
Mean time between failures/To repair failures
Average time to complete maintenance by lab personnel daily: 10 minutes; weekly: 20 minutes; monthly: 30 minutes
Onboard maintenance records/Maintenance training demo module no/no
List price/Targeted bed size or daily volume $194,040 (includes first year of service)/all bed sizes, all volumes
Annual service contract cost (24 hours/7 days)
Training provided with purchase/Advanced operator training 3 days on site/yes
Distinguishing features (supplied by company) fully automated benchtop analyzer with high throughput; unique menu; up to 15 assays onboard with ready-to-use, reagent-integral, random-access, batch and stat operation
Tabulation does not represent an endorsement by the College of American Pathologists.