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Siemens Healthcare Diagnostics, ADVIA 2400 (Chemistry 2012)

Siemens Healthcare Diagnostics, ADVIA 2400 (Chemistry 2012)

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Contact Information

Chemistry analyzer for high-volume laboratory
Siemens Healthcare Diagnostics Inc.
Colleen Wagener
colleen.wagener@siemens.com
1717 Deerfield Rd.
Deerfield, IL 60015
847-267-5441


Name of instrument/First year sold in U.S. ADVIA 2400/2003
List price/Total No. sold in 2012 $305,000/—
Number of units in clinical use in U.S./Outside U.S.
Where designed/Manufactured/Where reagents manufactured Japan/Japan/Ireland
Operational type/Reagent type random access/open reagent system
Sample handling system/Model type carousel, rack handler option, automation option/floor standing
Dimensions in inches (H x W x D)/Footprint in square feet 52.8 × 67.4 × 34/—
Number of tests for which analyzer has FDA-cleared applications >100
Tests released for clinical use in last 12 months ferritin, α1-acid glycoprotein, concentrated carbon dioxide, concentrated glucose hexokinase, concentrated glucose oxidase
Tests cleared but not released for clinical use myoglobin
Tests not available in U.S. but submitted for 510(k) clearance
Tests not available in U.S. but available in other countries
Research-use-only assays
Tests in development
Methodologies supported/immunoassay methodologies photometry, potentiometry turbidimetric/—
Number of direct ion-selective electrode channels 3
Number of different measured assays onboard simultaneously 46 colormetric, 3 ISE
Number of different assays programmed and calibrated at once 100
Number of user-definable (open) channels/Number active simultaneously 200/49
Number of different analytes for which system accommodates reagent containers onboard at once/Tests per container set 49/850
Shortest/Median onboard reagent stability/Refrigerated onboard 7 days/45 days/yes
Multiple reagent configurations supported yes
Reagent container placed directly on system for use yes
Instrument has same capabilities when third-party reagents used yes
Walkaway capacity in minutes/Specimens/Tests or assays 32,000 photometric
Uses disposable cuvettes/Maximum number stored no/340
Uses washable cuvettes/Replacement frequency yes/every 4 months
Minimum sample volume aspirated precisely at one time 2 µL of diluted specimen
Supplied with UPS (backup power)/Requires floor drain yes/yes (or sink)
Requires dedicated water system/Water consumption per hour yes/40 L
Noise generated in decibels <50
Dedicated pediatric sample cup/Dead volume yes/~50 µL
Primary tube sampling/Pierces caps on primary tubes yes/no
Sample bar-code reading capability/Autodiscrimination yes/—
Reagent bar-code reading capability yes
Bar code placement per CLSI standard Auto2A yes
Onboard test auto inventory (determines volume in container) yes
Measures number of tests remaining/Short sample detection/Clot detection yes/yes/yes
Hemolysis/Turbidity detection-quantitation yes/yes
Sample volume can be reduced yes
Increased to rerun out-of-linear-range high/low results yes
Autocalibration or autocalibration alert yes
Calibrants stored onboard/Multipoint calibration supported yes/yes
Typical calib. frequency for ISE/Metabolites/Therapeutic drugs/Drugs of abuse daily/45 days/30 days/30 days
Automatic shutdown programmable/Startup programmable yes/yes
Stat time to completion of all analytes and throughput per hour for:
• Sodium, potassium, chloride, TC02 5 minutes, —
• Sodium, potassium, chloride, TC02, glucose, urea, creatinine 10 minutes, —
• Albumin, direct and total bilirubin, AST, ALT, ALP 10 minutes, —
Typical time delay from ordering stat test to aspiration of sample 10 seconds
How often QC required/Onboard SW capability to review QC per laboratory protocol/yes
Onboard real-time QC/Support multiple QC lot numbers per analyte yes/yes
System can automatically transfer QC results to LIS yes
Data management capability/Instrument vendor supplies LIS interface yes/—
Interfaces to what LISs up and running in active user sites Soft, Misys, Cerner, Meditech, Multidata, Seacoast, Triple G, CCA, Computer Service and Support Q, Fletcher Flora, HDS, PSA consultants, Siemens, others
Bidirectional interface capability yes (broadcast download and host query)
Uses LOINC to transmit orders and results across interface yes
How labs get LOINC codes for reagent kits via software
Interface available (or will be) to automated specimen-handling system yes
Modem servicing available/System can diagnose own malfunctions/System can determine malfunctioning component yes/yes/yes
On-site time of service engineer generally <4 hours
Mean time between failures/Mean time to repair failures
Average time to complete maintenance by lab personnel automated daily maintenance
Onboard maintenance records/Maintenance training demo module —/yes
Training provided with instrument purchase yes
Distinguishing features (provided by vendor) comprehensive menu, including routine chemistry, TDMs, TAUs, special chemistry, and special proteins; provides unlimited open channels and walkaway capability (>450 specimens) when combined with the universal rack handler; offers micro-volume sample and reagent technology, multiple reagent wedge sizes, 2-second cycle time; fast throughput; sample-saver technology allows automatic repeats, dilutions, and reflex testing
Note: a dash in lieu of an answer means company did not answer question or question is not applicable