Webinars and Sponsored Roundtables — Register Now

Tuesday, April 28, 2026, 12:00 PM–1:00 PM ET
Discover how next-day comprehensive genomic profiling (CGP) is possible with the Oncomine Comprehensive Assay Plus on the Genexus System—delivering both speed and accuracy.

Webinar presenters Jane Bayani, MHSc, PhD, Assistant Professor and Co-Director, Diagnostic Development, Ontario Institute for Cancer Research, Canada, and Nicola Normanno, MD, Scientific Director, IRCCS Romagnolo Institute for the Study of Tumors, Italy, and Morten Grauslund, PhD, Molecular Biologist, Department of Pathology, Rigshospitalet/Copenhagen University Hospital, Copenhagen, Denmark.

Moderated by: Bob McGonnagle, Publisher, CAP TODAY

CAP TODAY does not endorse any of the products or services named within. The webinar is made possible by a special educational grant from Thermo Fisher Scientific. For Research Use Only. Not for use in diagnostic applications. 

Thursday, April 30, 2026, 11:00 AM–12:00 PM ET
Hear an expert discuss how Memorial Sloan Kettering Cancer Center (MSKCC) is utilizing
the oncoReveal® Nexus 21-gene panel to redefine turnaround time and actionable insights
in cancer care. Dr. Ewalt shares a perceptive look at the clinical need for rapid, front-line NGS sequencing, and how a unique, purpose built targeted NGS panel (Pillar Biosciences’ oncoReveal Nexus 21 gene Panel) was developed, validated and implemented clinically by Memorial Sloan Kettering Cancer Center (MSK-REACT) to complement their current comprehensive genomic profiling (CGP) approach.

Webinar presenter Mark Ewalt, MD, Associate Medical Director for Laboratory Operations for Diagnostic Molecular Pathology in the Molecular Diagnostics Service, Department of Pathology and Laboratory Medicine, MSKCC.

Moderated by: Bob McGonnagle, Publisher, CAP TODAY

CAP TODAY does not endorse any of the products or services named within. The webinar is made possible by a special educational grant from Pillar Biosciences.

Thursday, May 28, 2026, 1:00–2:00 PM ET
This session is designed to improve understanding and application of recent updates to synoptic pathology reporting protocols such as the latest Reporting Template for Reporting Results of Biomarker Testing of Specimens from Patients with Carcinoma of the Breast. These changes reflect evolving clinical guidelines that directly influence diagnostic accuracy and treatment selection in breast cancer care.

Webinar presenters Thaer Khoury, MD, FCAP, Chair, Pathology and Laboratory Medicine, Roswell Park Comprehensive Cancer Cente, and Colin Murphy,  CEO of mTuitive.

Moderated by: Bob McGonnagle, Publisher, CAP TODAY

Subspecialties

Interactive Product Guides

Product Spotlight

Illumina

NextSeq 550Dx

Name of system

NextSeq 550Dx

Company

Illumina

Email

[email protected]

City, State

San Diego, CA

Phone

858-202-4500

Website

https://www.illumina.com

System application/FDA cleared or approved

in vitro diagnostic and research use/yes

Country where designed/Manufactured

U.S./Singapore

First year sold in U.S./First year installed in U.S.

2017/2017

System sold internationally

yes (Canada, Europe, Greater China, Asia Pacific, more)

Dimensions of sequencer (H × W × D)/Footprint of sequencer

Accessory equipment supplied with sequencer at no cost

Type of computer supplied with sequencer

computer for analysis and operations combined

Analysis options provided with sequencer

onboard, cloud based

Where library preparation is performed

accessory equipment, wet bench

Bioinformatics tools provided with sequencer

onboard, cloud based

Sequencer supplied with UPS (uninterruptible power supply)

no

Electrical connection required for sequencer

100–120 VAC at 50/60 Hz

List price of entire sequencer and necessary components

$347,000

Purchase options

purchase, trade in, lease, reagent rental

Warranties offered

first year included with purchase; extended warranty available

Training included/Total time for basic training per operator

yes/2 days

Training location/Follow-up training available

at customer site/yes (extra charge)

Maximum No. of samples amplified in a single amplification event

384 samples (>384 samples with custom barcodes)

Read length/Percent bases >Q30

yes/2 × 150 bp/up to 350 bp

Paired-end capability/Tag lengths/Spans

yes/2 × 150 bp/up to 350 bp

Fragment/Tag lengths/Spans

yes/2 × 150 bp/up to 350 bp

Mate pair/Tag lengths/Spans

yes/2 × 150 bp/2–12 kb

Single end/Tag lengths/Spans

yes/up to 1 × 300 bp/up to 300 bp

RNA sequencing/Tag lengths/Spans

yes/up to 2 × 150 bp/up to 350 bp

ChIP sequencing/Tag lengths/Spans

yes/up to 2 × 150 bp/up to 350 bp

Bisulfite sequencing/Tag lengths/Spans

yes/up to 2 × 150 bp/up to 350 bp

Maximum No. of reads or fragments sequenced per single-end run

>300 million

Maximum No. of reads or fragments sequenced per paired-end run

>600 million

Total No. of nucleotides (bases) sequenced per run

up to 120 gb

Wet lab bench time for sequencing preparation

10 minutes

Sequencing run time

<36 hours

Total time for generating standard gDNA library

<3.5 hours (with Illumina DNA Prep)

• Paired end

<3.5 hours (with Illumina DNA Prep)

• Fragment

<7 hours (with AmpliSeq for Illumina); <6.5 hours (with Illumina DNA Prep with Enrichment)

• Paired end

• Fragment

• Mate pair

• Single end

<4 hours (with TruSeq Small RNA)

• RNA sequencing

<3 hours

• ChIP sequencing

• Bisulfite sequencing

Library preparation integrated in system as standard offering

no

Library preparation offered separately for additional charge

no

Cost of sequencing reagents per run

Reagent tracking method

RFID

• Type of reagent information tracked

serial No., expiration date, lot and part Nos., No. of cycles

Shipping conditions for amplification/sequencing reagents

Storage conditions for amplification/sequencing reagents

—/reagent cartridge, HT1 buffer: -15°– -25°C; flow cell: 2°–8°C; buffer cartridge: 15°–30°C

Shelf life of amplification/sequencing reagents

guaranteed 3 months/guaranteed 3 months

System requires a control sample on sequencing run 

yes

• Company offers a sequencing control

yes (additional charge)

Sequencing system control software and devices to start run/for data analysis

NextSeq 550Dx Control Software and Operating Software/Local Run Manager, BaseSpace Sequence Hub

Complete walkaway automation for amplification, sequencing, and variant calling

yes

Remote system monitoring

yes

Total time required for setup of amplification, sequencing, and variant calling steps

10 minutes

Maximum No. of libraries sequenced in a single run

384 samples (>384 samples with custom barcodes)

System includes secondary data-analysis software developed by company

yes (BaseSpace Sequence Hub)

System includes post-sequencing data-analysis software

yes

Mutations detectable via data-analysis software

substitutions, indels, copy number changes

System can generate a variant report

yes

Types of maintenance plans available/mean time between failures

parts only, bronze, silver, gold, Dx, dedicated on-site/—

No. of field application scientists and engineers based in U.S.

>500

• Weekly

none (manual wash if instrument idle for 2 weeks)

• Monthly

none

• Pre-run

none (automatic wash completed after every run)

Distinguishing features of NGS system (supplied by company)Note: a dash in lieu of an answer means company did not answer question or question is not applicable

analyzes solid tumors using minimal tissue with TruSight Oncology Comprehensive, a reimbursable, validated, FDA-cleared test for in vitro diagnostics; runs IVD assays and laboratory-developed tests; 21 CFR part 11 compliant software

More products
in this guide

MiSeq i100 Plus
NextSeq 1000; NextSeq 2000
NovaSeq 6000Dx
NovaSeq X; NovaSeq X Plus
Ion GeneStudio S5 System
Ion Torrent Genexus Integrated Sequencer; Ion Torrent Genexus Dx Integrated Sequencer