Tuesday, June 9, 2026, 1:00–2:00 PM ET
In this webinar, we will examine how immune recognition after allogeneic HCT can influence leukemia relapse and disease progression. The session will highlight the clinical relevance of HLA loss of heterozygosity (LOH), approaches used for its detection, and how LOH findings may support transplant strategies, including considerations for donor selection in subsequent transplantation.
Webinar presenter Alberto Cardoso Martins Lima, PhD, Clinical consulting scientist in histocompatibility,
specializing in allogeneic hematopoietic cell transplantation (HCT) at IGEN/AFIP São Paulo and CHC/UFPR in Curitiba, Brazil
Moderated by: Bob McGonnagle, Publisher, CAP TODAY
Wednesday, June 24, 2026, 12:00–1:00 PM ET
Hear an expert discuss the expanded clinical utility of HER2 IHC scoring in metastatic breast cancer and its impact on your practice
Webinar presenter Michelle Shiller, DO, AP, CP, MGP, FACP, Baylor University Medical Center.
Moderated by: Bob McGonnagle, Publisher, CAP TODAY
Wednesday, July 15, 2026, 1:00-2:00 PM ET
Hear an expert discuss how to integrate Kappa and Lambda in situ hybridization testing into your standard hematopathology workflow to accurately assess B-cell and plasma cell clonality. You will also gain the skills to recognize testing pitfalls in challenging reactive versus neoplastic proliferations and apply ancillary tools to resolve complex cases.
Webinar presenter Xiaojun Wu, MD, PhD, Assistant professor, Director of Hematopathology Section at NCR of Johns Hopkins Medicine Department of Pathology, SOM at Johns Hopkins University
Moderated by: Bob McGonnagle, Publisher, CAP TODAY
May 2026—When it comes to cancer mutations, there are big fish in little ponds, and little fish in big ponds, and big fish in big ponds, and little fish in little ponds. The ESR1 mutation and its emergence in advanced breast cancer is still deciding what stripe of fish it is—or rather, breast specialists, researchers, and the FDA are in the midst of figuring out potentially important uses …
May 2026—The fast-changing world of sequencing was the topic that a panel of pathologists and industry representatives dug into in a Feb. 27 online roundtable, led by CAP TODAY publisher Bob McGonnagle.
April 2026—It’s hard to mount an argument against the Great Plains. Nor is there much reason to. But drive across eastern Colorado, Nebraska, Kansas, or the Dakotas, and it is a bona fide thrill to arrive in Wyoming’s northwest corner and see the Grand Tetons rising up in spectacular fashion.
February 2026—Rapid genome sequencing in neonatal intensive care units is a complex process involving a multidisciplinary team, including pathologists, genetic counselors, and clinicians. The goal is to identify genetic causes of complex medical conditions in newborns, often born prematurely with multiple health issues.
February 2026—A six-year-old boy presented with abdominal pain and was found to have a large mediastinal mass. Biopsy revealed a spindle cell sarcoma, and molecular testing identified an NTRK1 rearrangement, confirming the diagnosis of NTRK1-rearranged spindle cell sarcoma.
February 2026—CAP TODAY publisher Bob McGonnagle spoke on Dec. 2, 2025 with Steve Swartzell and Scott Johnston of ELITechGroup. McGonnagle’s questions and their answers follow. A few of the questions came from the roundtable audience and are identified as such.
Bob McGonnagle: Steve, how long have you been with ELITech and what is your background in molecular diagnostics?
Steve Swartzell: I am director of customer experience and have been with ELITechGroup for 22 years. My background is in microbiology. I started as a research scientist in R&D and I was an application specialist working directly with customers. I have many years of lab experience as well. Now I oversee all the field activities for ELITechGroup MDx in the U.S. Continue reading …
Watch the full conversation:
This roundtable discussion is sponsored by ELITechGroup.
December 2025—Bringing next-generation sequencing (NGS) in-house can be approached in two ways: a rapid, comprehensive implementation or a gradual, progressive build. Florida Cancer Specialists opted for a rapid approach, starting with a complex pancancer solid tumor panel, which facilitated the addition of smaller assays.
December 2025—The absence of CDC surveillance data due to the government shutdown has created uncertainty about the severity and impact of the current respiratory virus season. While regional public health surveillance provides some insights, concerns remain about the potential for a severe season, exacerbated by vaccine hesitancy and changes in vaccine guidance.
December 2025—A 21-year-old male with a history of acute promyelocytic leukemia (APL) presented with symptoms suggestive of relapse. While standard tests like qRT-PCR and amplicon-based sequencing failed to detect the PML::RARA fusion, AMP NGS revealed an atypical bcr2 transcript with a novel breakpoint.
October 2025—Bringing equity to cystic fibrosis carrier and newborn screening was the aim of expert groups that have released their recommendations for both. Carrier screening for 23 CFTR variants, which had been the recommended practice since 2004, was working well, “but only if a person was of white European or Ashkenazi Jewish ancestry,” said Karen Raraigh, MGC, CGC, assistant professor of genetic medicine at Johns Hopkins University. “It wasn’t working all that well because it was not an equitable test.” For people of Asian American and African American ancestry, she said, the detection rate was lower.
