Webinars and Sponsored Roundtables — Register Now

Tuesday, April 28, 2026, 12:00 PM–1:00 PM ET
Discover how next-day comprehensive genomic profiling (CGP) is possible with the Oncomine Comprehensive Assay Plus on the Genexus System—delivering both speed and accuracy.

Webinar presenters Jane Bayani, MHSc, PhD, Assistant Professor and Co-Director, Diagnostic Development, Ontario Institute for Cancer Research, Canada, and Nicola Normanno, MD, Scientific Director, IRCCS Romagnolo Institute for the Study of Tumors, Italy, and Morten Grauslund, PhD, Molecular Biologist, Department of Pathology, Rigshospitalet/Copenhagen University Hospital, Copenhagen, Denmark.

Moderated by: Bob McGonnagle, Publisher, CAP TODAY

CAP TODAY does not endorse any of the products or services named within. The webinar is made possible by a special educational grant from Thermo Fisher Scientific. For Research Use Only. Not for use in diagnostic applications. 

Thursday, April 30, 2026, 11:00 AM–12:00 PM ET
Hear an expert discuss how Memorial Sloan Kettering Cancer Center (MSKCC) is utilizing
the oncoReveal® Nexus 21-gene panel to redefine turnaround time and actionable insights
in cancer care. Dr. Ewalt shares a perceptive look at the clinical need for rapid, front-line NGS sequencing, and how a unique, purpose built targeted NGS panel (Pillar Biosciences’ oncoReveal Nexus 21 gene Panel) was developed, validated and implemented clinically by Memorial Sloan Kettering Cancer Center (MSK-REACT) to complement their current comprehensive genomic profiling (CGP) approach.

Webinar presenter Mark Ewalt, MD, Associate Medical Director for Laboratory Operations for Diagnostic Molecular Pathology in the Molecular Diagnostics Service, Department of Pathology and Laboratory Medicine, MSKCC.

Moderated by: Bob McGonnagle, Publisher, CAP TODAY

CAP TODAY does not endorse any of the products or services named within. The webinar is made possible by a special educational grant from Pillar Biosciences.

Thursday, May 28, 2026, 1:00–2:00 PM ET
This session is designed to improve understanding and application of recent updates to synoptic pathology reporting protocols such as the latest Reporting Template for Reporting Results of Biomarker Testing of Specimens from Patients with Carcinoma of the Breast. These changes reflect evolving clinical guidelines that directly influence diagnostic accuracy and treatment selection in breast cancer care.

Webinar presenters Thaer Khoury, MD, FCAP, Chair, Pathology and Laboratory Medicine, Roswell Park Comprehensive Cancer Cente, and Colin Murphy,  CEO of mTuitive.

Moderated by: Bob McGonnagle, Publisher, CAP TODAY

Subspecialties

Interactive Product Guides

Product Spotlight

Roche Diagnostics

cobas pro integrated solutions

Company

Roche Diagnostics

Name of instrument

cobas pro integrated solutions

Contact

John Kleinschmidt  

Email

john.kleinschmidt@roche.com

City, State

Indianapolis, IN

Phone

800-428-5074

Website

go.roche.com/cobasproUSA

Type of instrument

combination chemistry/immunoassay

Operational type/Model type

random access, continuous random access/floor standing

List price/First year sold in U.S.

—/2019

Targeted hospital bed size/Targeted test volume

> 150/daily: > 150; monthly: > 2, 000; annual: > 750, 000–4.5 million

Company manufactures instrument

no (manufactured by Hitachi High-Technologies)

Other models in this family of analyzers

cobas pure integrated solutions

No. of units in clinical use in U.S./Outside U.S. (countries)

> 1, 000/> 5, 000 (> 40 countries)

Dimensions (H × W × D)/Instrument footprint

56 x 172.2 x 47 in. for integrated 2-module system/54 sq. ft. 

Weight empty/Weight fully loaded

4, 388 lbs./4, 388 lbs.

No. of different measured assays onboard simultaneously

chem: 63 (63 can be run and calibrated at one time);  immuno: 48 (48 can be run and calibrated at one time)

No. of user-definable (open chemistry) channels

10 (10 can be active simultaneously)

Test throughput per hour/Assay run time

up to 2, 200 (up to 111 tests in throughput)/chem: 4.5–10 min. (avg. 10 min.); immuno: 9–27 min. (avg. 18 min.)

No. of direct ion-selective electrode channels

3 indirect

Detection methods

photometry, potentiometry

• Ion-selective electrode

4.5 min. for ISE, 10 min. with CO2/300 specimens per hr.

• Basic metabolic panel

10 min./200 specimens per hr.

• Complete metabolic panel

10 min./100 specimens per hr.

Typical time delay from ordering stat test until aspiration of sample

< 1 min.

Fully automated microplate immunoassay system

no

Methodologies supported

electrochemiluminescence

Separation methodologies

magnetic particle

Stat time until completion of a ß-hCG test

~10 min.

Stat time until completion of a cTn test

~10 min.

• Typical time delay from test order to aspiration of sample

< 1 min.

Approximate No. of tests per reagent set/Reagent type

up to 3, 300 (chemistry), up to 300 (immunoassay)/self-contained multiuse

Reagents refrigerated onboard/Reagents ready to use

yes (5°–15°C [chemistry], 6°–10°C [immunoassay])/yes

Reagent lot tracking/Reagent inventory

yes/yes

Reagent form/Reagents barcoded

liquid chemistry (open reagent system)/yes

Separate reagent pack for each specimen/for each test run

no/yes

Walkaway capability/Walkaway duration

yes/30–45 min. or 300 samples or ~3, 000 tests

Design of sample-handling system

5-position rack

Uses washable cuvettes/Uses disposable cuvettes

yes (can store up to 221 cuvettes for chem, 1, 575 for immuno)/yes

Min.–max. sample volume that can be aspirated at one time 

1–60 xL

Min. reaction volume/Min. specimen volume/Min. dead volume

75 xL/1.5 xL (chem), 4 xL (immuno)/50 xL

Dedicated pediatric sample cup

yes (dead volume: 50 µL)

Primary tube sampling

yes

Accommodates most standard tube sizes/Accepts nonstandard tube sizes

yes/yes (11 x 102 mm [chem], 13 x 102 mm [immuno])

Pierces caps on primary tubes

no

Protects against probe collision

yes

Detects clots/liquid level/short sample

yes/yes/yes

Detection or quantitation for hemolysis, icterus, lipemia, clots

quantitation for hemolysis, icterus, lipemia; detection for clots

Dilutes patient samples onboard/Susceptibility to carryover

yes (can be programmed to perform dilutions prior to analysis)/<1 part per million (chemistry), no carryover (immunoassay)

Sample volume can be diluted to rerun out-of-linear-range high results

yes

Sample volume can be concentrated to rerun out-of-linear-range low results

yes

Analyzer requires dedicated water supply

yes (32 L/hr. consumption during operation for chemistry, 30 L/hr. for immunoassay)

Autocalibration/Multipoint calibration supported

yes (calibrants are not stored onboard)/yes (recommended avg. frequency: once per lot [chem], up to 84 days per lot [immuno])

Typical calibration frequency for ISE/therapeutic drugs/drugs of abuse/general chemistries/immunoassays

once per lot/once per lot/once per lot/once per lot/up to 84 days per lot

Automatic programmable start/Automatic programmable shutdown

yes (6.5 min. start-up time)/yes

Supports multiple QC lot numbers per analyte

yes

Waste management

direct to drain

Sample barcode-reading capability/Autodiscrimination

yes (Interleaved 2 of 5, Codabar, Code 39, Code 128)/yes

Lab can control analyzer from remote computer

yes

Instrument can diagnose its own malfunctions

yes (operator intervention required to order parts)

System malfunctions can be diagnosed via remote monitoring

yes

UPS backup power supply

yes

Data-management capability/LIS or EHR systems interfaced

onboard, optional add-on (Bio-Rad MAS)/SCC, Cerner, Epic, more

LIS interface provided/Bidirectional interface capability

yes (incl. in price)/yes (broadcast download and host query)

Modem servicing provided/Service engineer on-site response time

yes/—

Mean time between failures

c 503 module: 220 days; e 801 module: avg. 220 days (displays error codes for troubleshooting)

Average scheduled maintenance time by lab personnel

daily: ~5 min.; weekly: 0 min.; monthly: ~59 min.

Maintenance records kept onboard for user/vendor

yes/yes (both include audit trail of who replaced parts)

Maintenance training demonstration module onboard

yes

Training included with purchase/Avg. time for basic user training

yes (~2 training slots per module)/~5 days (at customer and vendor sites)

Advanced operator training/Extra charge for follow-up or advanced training

yes (at vendor site)/yes (cost varies by contract)

Warranty provided/Cost of annual service contract (24 h/7 d)

yes (1 year)/varies by contract

Distinguishing features (supplied by company)

minimal operator intervention with automated maintenance, automated calibration, and continuous loading of reagents; long onboard reagent (up to 6 months) and calibration stabilities; increase revenue through expanded testing services with broad menu on consolidated platform and fast incubation times

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