Webinars and Sponsored Roundtables — Register Now

Thursday, May 28, 2026, 1:00–2:00 PM ET
This session is designed to improve understanding and application of recent updates to synoptic pathology reporting protocols such as the latest Reporting Template for Reporting Results of Biomarker Testing of Specimens from Patients with Carcinoma of the Breast. These changes reflect evolving clinical guidelines that directly influence diagnostic accuracy and treatment selection in breast cancer care.

Webinar presenters Thaer Khoury, MD, FCAP, Chair, Pathology and Laboratory Medicine, Roswell Park Comprehensive Cancer Center, and Colin Murphy,  CEO of mTuitive.

Moderated by: Bob McGonnagle, Publisher, CAP TODAY

Tuesday, June 9, 2026, 1:00–2:00 PM ET
In this webinar, we will examine how immune recognition after allogeneic HCT can influence leukemia relapse and disease progression. The session will highlight the clinical relevance of HLA loss of heterozygosity (LOH), approaches used for its detection, and how LOH findings may support transplant strategies, including considerations for donor selection in subsequent transplantation.

Webinar presenter Alberto Cardoso Martins Lima, PhD, Clinical consulting scientist in histocompatibility,
specializing in allogeneic hematopoietic cell transplantation (HCT) at IGEN/AFIP São Paulo and CHC/UFPR in Curitiba, Brazil

Moderated by: Bob McGonnagle, Publisher, CAP TODAY

Wednesday, June 24, 2026, 12:00–1:00 PM ET
Hear an expert discuss the expanded clinical utility of HER2 IHC scoring in metastatic breast cancer and its impact on your practice

Webinar presenter Michelle Shiller, DO, AP, CP, MGP, FACP, Baylor University Medical Center.

Moderated by: Bob McGonnagle, Publisher, CAP TODAY

Subspecialties

Interactive Product Guides

Product Spotlight

Chrono-log Corp.

Optical Aggregation Systems Models 490 4+ | 490 4+4

Company

Chrono-log Corp.

Instrument name/First year sold

Optical Aggregation Systems Models 490 4+, 490 4+4/2017

Contact

Sal Pema

Email

sal@chronolog.com

City, State

Havertown, PA

Phone

610-853-1130 or 800-247-6665 

Website

https://www.chronolog.com

List price/Model type

$11, 551–$27, 505/benchtop

No. of units in clinical use in U.S./Outside U.S.

Composition of installs: Hospital lab/Reference lab/Other

Targeted daily, monthly, annual test volume

Operational type

discrete

Country where analyzer designed/Manufactured

U.S./U.S.

Company manufactures instrument

yes (also sold via distribution partners)

FDA-approved clotting-based tests

FDA-approved chromogenic tests

FDA-approved immunologic tests

platelet agglutination with ristocetin

Other FDA-approved tests

LTA platelet aggregation, ristocetin cofactor assay

User-defined tests in clinical use

LTA platelet aggregation, ristocetin cofactor assay

Tests in development or awaiting FDA 510(k) clearance

Methodologies supported

turbidimetric for measuring platelet aggregation in PRP and ristocetin cofactor assay

Number of different measured assays onboard simultaneously

4–8

Number of different assays programmed and calib. at one time

4–8

No. of user-definable (open) channels/No. active simultaneously

4–8/4–8

Factor assays require manual manipulation or dilutions

yes (manual dilutions)

Test throughput per hour/Assay run time

6 (24–48 tests in throughput)/5 min. minimum

Design of sample-handling system

manual

Operates on whole blood or spun plasma

spun plasma

Reagent type

self-contained multiuse vials; open reagent system (liquid, lyophilized [reconstituted manually])

Reagent barcode-reading capability

no

No. of reagent containers held onboard/Reagents ready to use

—/requires operator prehandling

Reagent lot tracking/Reagent inventory/Reagents refrigerated onboard

no/no/no

Reagents, consumables loaded without interrupting testing

yes (consumables)

Instrument uses proprietary or third-party reagents

proprietary reagents

Maximum time same lot number of reagents can be used

18 months–3 years

Walkaway capability/Walkaway duration

yes/5 min. or 4–8 specimens or 4–8 tests

Min.–max. specimen volume that can be aspirated at one time

250–500 µL

Min. sample volume required for PT/PTT/Factor VIII activity

cuvettes, stir bars, pipette tips

Primary tube sampling supported/Pierces caps on primary tubes

no/no

Accommodates most standard tube sizes/Nonstandard sizes

no/no

Sample barcode-reading capability/Autodiscrimination

no/no

More products
in this guide

PAP-8E Platelet Aggregometer
Whole Blood Optical Lumi-Aggregation System 700-2 | 700-4
Quantra Hemostasis Analyzer
Sysmex CA-600 Series Systems: CA-620 | CA-660
Sysmex CS-2500 System
Sysmex CS-5100 System
ACL TOP 550 CTS
ACL TOP 750 Series
ACL TOP 770/770s
ACL TOP 770 LAS