September 2021—Agilent Technologies announced that its PD-L1 IHC 22C3 pharmDx assay is CE-IVD marked for use as an aid in identifying esophageal cancer patients for treatment with Keytruda using a combined positive score of ≥10. In Europe, Keytruda (Merck) is approved in combination with platinum- and fluoropyrimidine-based chemotherapy for patients with locally advanced unresectable or metastatic esophageal carcinoma or HER2-negative gastroesophageal junction adenocarcinoma whose tumors express PD-L1 (CPS ≥10).
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