October 2025—Agilent Technologies MMR IHC Panel pharmDx (Dako Omnis) has received FDA approval as a companion diagnostic test for colorectal cancer. The test aids in identifying mismatch repair deficient colorectal cancer patients who are eligible for treatment with Bristol Myers Squibb’s Opdivo (nivolumab) or Opdivo in combination with Yervoy (ipilimumab). It was developed and validated to detect the loss of function of any of the four MMR proteins in formalin-fixed, paraffin-embedded colorectal cancer tissue.
The panel is approved for use with the Agilent Dako Omnis automated staining solution.
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