Webinars and Sponsored Roundtables — Register Now
Thursday, May 28, 2026, 1:00–2:00 PM ET
This session is designed to improve understanding and application of recent updates to synoptic pathology reporting protocols such as the latest Reporting Template for Reporting Results of Biomarker Testing of Specimens from Patients with Carcinoma of the Breast. These changes reflect evolving clinical guidelines that directly influence diagnostic accuracy and treatment selection in breast cancer care.
Webinar presenters Thaer Khoury, MD, FCAP, Chair, Pathology and Laboratory Medicine, Roswell Park Comprehensive Cancer Cente, and Colin Murphy, CEO of mTuitive.
Moderated by: Bob McGonnagle, Publisher, CAP TODAY
Tuesday, June 9, 2026, 1:00–2:00 PM ET
In this webinar, we will examine how immune recognition after allogeneic HCT can influence leukemia relapse and disease progression. The session will highlight the clinical relevance of HLA loss of heterozygosity (LOH), approaches used for its detection, and how LOH findings may support transplant strategies, including considerations for donor selection in subsequent transplantation.
Webinar presenter Alberto Cardoso Martins Lima, PhD, Clinical consulting scientist in histocompatibility,
specializing in allogeneic hematopoietic cell transplantation (HCT) at IGEN/AFIP São Paulo and CHC/UFPR in Curitiba, Brazil
Moderated by: Bob McGonnagle, Publisher, CAP TODAY
Wednesday, June 24, 2026, 12:00–1:00 PM ET
Hear an expert discuss the expanded clinical utility of HER2 IHC scoring in metastatic breast cancer and its impact on your practice
Webinar presenter Michelle Shiller, DO, AP, CP, MGP, FACP, Baylor University Medical Center.
Moderated by: Bob McGonnagle, Publisher, CAP TODAY
Subspecialties
Interactive Product Guides
Product Spotlight
Chrono-log Corp.
| Company | Chrono-log Corp. |
|---|---|
| Instrument name | Optical Aggregation Systems Models 490 4+, 490 4+4 |
| Contact | Sal Pema |
| City State | Havertown, PA |
| Phone | 610-853-1130 or 800-247-6665 |
| Website | |
| First year sold | 2017 |
| List price/Model type | —/benchtop |
| Dimensions (H × W × D)/Weight/Instrument footprint | per each 4-channel module: 8.5 × 14 × 15 in./19.3 lbs./1.5 sq. ft. |
| No. of units in clinical use in U.S./Outside U.S. | — |
| Composition of installs: Hospital lab/Reference lab/Other | — |
| Targeted daily, monthly, annual test volume | — |
| Operational type | discrete |
| Country where analyzer designed/Manufactured | U.S./U.S. |
| Company manufactures instrument | yes (also sold via distribution partners) |
| FDA-approved clotting-based tests | — |
| FDA-approved chromogenic tests | — |
| FDA-approved immunologic tests | platelet agglutination with ristocetin |
| Other FDA-approved tests | LTA platelet aggregation, ristocetin cofactor assay |
| User-defined tests in clinical use | LTA platelet aggregation, ristocetin cofactor assay |
| Tests in development or awaiting FDA 510(k) clearance | — |
| Methodologies supported | turbidimetric for measuring platelet aggregation in PRP and ristocetin cofactor assay |
| Number of different measured assays onboard simultaneously | 4–8 |
| Number of different assays programmed and calib. at one time | 4–8 |
| No. of user-definable (open) channels/No. active simultaneously | 4–8/4–8 |
| Factor assays require manual manipulation or dilutions | yes (manual dilutions) |
| Test throughput per hour/Assay run time | 6 (24–48 tests in throughput)/5 min. minimum |
| Design of sample-handling system | manual |
| Operates on whole blood or spun plasma | spun plasma |
| Reagent type | self-contained multiuse vials; open reagent system (liquid, lyophilized [reconstituted manually]) |
| Reagent barcode-reading capability | no |
| No. of reagent containers held onboard/Reagents ready to use | —/requires operator prehandling |
| Reagent lot tracking/Reagent inventory/Reagents refrigerated onboard | no/no/no |
| Reagents, consumables loaded without interrupting testing | yes (consumables) |
| Instrument uses proprietary or third-party reagents | proprietary reagents |
| Maximum time same lot number of reagents can be used | 18 months–3 years |
| Walkaway capability/Walkaway duration | yes/5 min. or 4–8 specimens or 4–8 tests |
| Min.–max. specimen volume that can be aspirated at one time | 250–500 µL |
| Min. sample volume required for PT/PTT/Factor VIII activity | — |
| Types of disposables used | cuvettes, stir bars, pipette tips |
| Primary tube sampling supported/Pierces caps on primary tubes | no/no |
| Accommodates most standard tube sizes/Nonstandard sizes | no/no |
| Sample barcode-reading capability/Autodiscrimination | no/no |
| Auto tracks product volume/Measures number of tests remaining | no/no |
| Short sample detection | no |
| Clot detection as preanalytical variable in plasma sample | no |
| Auto detects adequate reagents for aspiration or analysis | no |
| Detection or quantitation for hemolysis, turbidity, icterus, lipemia | no |
| Dilutes patient samples onboard | no |
| Automatic rerun capability/Auto reflex testing capability | yes/no |
| Lag time during which hypercoagulable sample not detected | no |
| User can adjust reagent volumes/Sample volumes | yes/yes |
| User can adjust No. of reagents/Sources of reagents | yes/yes |
| User can adjust incubation times/Reading times | yes/yes |
| Autocalibration/Calibrants stored onboard | yes/no |
| Multipoint calibration supported/Recommended frequency | yes/annually |
| • PT alone | — |
| • PT, PTT | — |
| • Fibrinogen | — |
| • Factor VIII activity assay | — |
| • D-dimer | — |
| Time delay from ordering stat to aspiration of sample | — |
| How labs get LOINC codes for results | email query |
| Onboard real-time QC/Onboard software capability to review QC | yes/no |
| Information that can be barcode-scanned on instrument | barcode scanning not offered |
| Compatible with laboratory automation systems | no |
| Data-management capability/LIS or EHR systems interfaced | onboard/none |
| Interface supplied by instrument vendor | no |
| Results transferred to LIS as soon as test time complete | no |
| Bidirectional interface capability | no |
| Remote servicing provided/UPS backup power supply | no/no |
| Instrument connections to transfer information | — |
| Interface standards supported | — |
| Information transferred to data-management software | — |
| Avg. time for basic user training | — |
| Approximate scheduled maintenance time | preventive maintenance and calibration by clinical engineering recommended annually |
| Maintenance records kept onboard | yes |
| Warranty with purchase/Annual service contract cost (24/7) | yes/— (cost dependent on contract) |
| Distinguishing features (supplied by company) | continuously monitors and regulates temperature and stirring; optical calibration can be performed by laboratory personnel using no-cost water samples; customized color-coding options |