Webinars and Sponsored Roundtables — Register Now

Tuesday, April 28, 2026, 12:00 PM–1:00 PM ET
Discover how next-day comprehensive genomic profiling (CGP) is possible with the Oncomine Comprehensive Assay Plus on the Genexus System—delivering both speed and accuracy.

Webinar presenters Jane Bayani, MHSc, PhD, Assistant Professor and Co-Director, Diagnostic Development, Ontario Institute for Cancer Research, Canada, and Nicola Normanno, MD, Scientific Director, IRCCS Romagnolo Institute for the Study of Tumors, Italy, and Morten Grauslund, PhD, Molecular Biologist, Department of Pathology, Rigshospitalet/Copenhagen University Hospital, Copenhagen, Denmark.

Moderated by: Bob McGonnagle, Publisher, CAP TODAY

CAP TODAY does not endorse any of the products or services named within. The webinar is made possible by a special educational grant from Thermo Fisher Scientific. For Research Use Only. Not for use in diagnostic applications. 

Thursday, April 30, 2026, 11:00 AM–12:00 PM ET
Hear an expert discuss how Memorial Sloan Kettering Cancer Center (MSKCC) is utilizing
the oncoReveal® Nexus 21-gene panel to redefine turnaround time and actionable insights
in cancer care. Dr. Ewalt shares a perceptive look at the clinical need for rapid, front-line NGS sequencing, and how a unique, purpose built targeted NGS panel (Pillar Biosciences’ oncoReveal Nexus 21 gene Panel) was developed, validated and implemented clinically by Memorial Sloan Kettering Cancer Center (MSK-REACT) to complement their current comprehensive genomic profiling (CGP) approach.

Webinar presenter Mark Ewalt, MD, Associate Medical Director for Laboratory Operations for Diagnostic Molecular Pathology in the Molecular Diagnostics Service, Department of Pathology and Laboratory Medicine, MSKCC.

Moderated by: Bob McGonnagle, Publisher, CAP TODAY

CAP TODAY does not endorse any of the products or services named within. The webinar is made possible by a special educational grant from Pillar Biosciences.

Thursday, May 28, 2026, 1:00–2:00 PM ET
This session is designed to improve understanding and application of recent updates to synoptic pathology reporting protocols such as the latest Reporting Template for Reporting Results of Biomarker Testing of Specimens from Patients with Carcinoma of the Breast. These changes reflect evolving clinical guidelines that directly influence diagnostic accuracy and treatment selection in breast cancer care.

Webinar presenters Thaer Khoury, MD, FCAP, Chair, Pathology and Laboratory Medicine, Roswell Park Comprehensive Cancer Cente, and Colin Murphy,  CEO of mTuitive.

Moderated by: Bob McGonnagle, Publisher, CAP TODAY

Subspecialties

Interactive Product Guides

Product Spotlight

Roche Diagnostics

cobas 8000 modular analyzer series

Company

Roche Diagnostics

Name of instrument

cobas 8000 modular analyzer series

Contact

John Kleinschmidt  

Email

john.kleinschmidt@roche.com

City, State

Indianapolis, IN

Phone

800-428-5074  

Website

diagnostics.roche.com/us/en/home.html

Type of instrument

combination chemistry/immunoassay

Operational type/Model type

random access, continuous random access/floor standing

List price/First year sold in U.S.

—/2010

Targeted hospital bed size/Targeted test volume

> 250/daily: > 4, 000; annual: ≥ 2, 500, 000

Company manufactures instrument

no (manufactured by Hitachi High-Technologies)

Other models in this family of analyzers

chem.: cobas c 701, c 702, c 502; immuno.: cobas e 801, e 602

No. of units in clinical use in U.S./Outside U.S. (countries)

> 400/> 5, 000 (49 countries)

Dimensions (H × W × D)/Instrument footprint

40–53 x 99–294 x 45 in./66.35 sq. ft. for 3-module config.

Weight empty/Weight fully loaded

1, 150–5, 485 lbs./1, 150–5, 485 lbs.

No. of different measured assays onboard simultaneously

up to 283 (> 300 can be run and calibrated at one time)

No. of user-definable (open chemistry) channels

10 for c 70x, c 502 (all can be active simultaneously)

Test throughput per hour/Assay run time

up to 9, 800 (varies by module)/ISE: 12 sec.; chemistry: 3–10 min. in 1-min. steps; immunoassay: 9–27 min. (avg. 18 min.)

No. of direct ion-selective electrode channels

3 indirect

Detection methods

photometry, potentiometry

• Ion-selective electrode

4.5 min./600 specimens per hr.

• Basic metabolic panel

7 min./up to 400 specimens per hr.

• Complete metabolic panel

10 min./up to 181 specimens per hr.

Typical time delay from ordering stat test until aspiration of sample

< 1 min.

Fully automated microplate immunoassay system

no

Methodologies supported

electrochemiluminescence

Separation methodologies

magnetic particle

Stat time until completion of a ß-hCG test

~10 min.

Stat time until completion of a cTn test

9 min.

• Typical time delay from test order to aspiration of sample

24 sec.

Approximate No. of tests per reagent set/Reagent type

up to 3, 000 per pack (chemistry), up to 300 per pack (immunoassay)/self-contained multiuse

Reagents refrigerated onboard/Reagents ready to use

yes (5°–15°C [chem], 6°–10°C [immuno])/reagent specific

Reagent lot tracking/Reagent inventory

yes/yes

Reagent form/Reagents barcoded

liquid chemistry (open reagent system)/yes

Separate reagent pack for each specimen/for each test run

no/no

Walkaway capability/Walkaway duration

yes/45 min. or 300 samples or 3, 000 tests

Design of sample-handling system

5-position rack

Uses washable cuvettes/Uses disposable cuvettes

yes (No. of cuvettes stored varies by module)/no

Min.–max. sample volume that can be aspirated at one time 

1–35 xL (chemistry), 1–60 xL (immunoassay)

Min. reaction volume/Min. specimen volume/Min. dead volume

100–250 xL (chem), 120–200 xL (immuno)/1 xL (chem), 4–10 xL (immuno)/50–1, 000 µL (container dependent) 

Dedicated pediatric sample cup

yes (dead volume: 50 µL)

Primary tube sampling

yes

Accommodates most standard tube sizes/Accepts nonstandard tube sizes

yes/yes

Pierces caps on primary tubes

no

Protects against probe collision

yes

Detects clots/liquid level/short sample

yes/yes/yes

Detection or quantitation for hemolysis, icterus, lipemia, clots

quantitation for hemolysis, icterus, lipemia; detection for clots

Dilutes patient samples onboard/Susceptibility to carryover

yes (can be programmed to perform dilutions prior to analysis)/<1 part per million (chemistry), no carryover (immunoassay)

Sample volume can be diluted to rerun out-of-linear-range high results

yes

Sample volume can be concentrated to rerun out-of-linear-range low results

yes

Analyzer requires dedicated water supply

yes (10–36 L/hr. consumption during operation for chemistry, 12–30 L/hr. for immunoassay)

Autocalibration/Multipoint calibration supported

yes (calibrants are not stored onboard)/yes (recommended avg. frequency: 24 hrs. [ISE], once per lot [chemistry], up to 84 days per lot [immunoassay])

Typical calibration frequency for ISE/therapeutic drugs/drugs of abuse/general chemistries/immunoassays

24 hrs./once per lot/42 days per lot/once per lot/up to 84 days per lot

Automatic programmable start/Automatic programmable shutdown

yes (6.5 min. start-up time)/yes

Supports multiple QC lot numbers per analyte

yes

Waste management

direct to drain

Sample barcode-reading capability/Autodiscrimination

yes (Interleaved 2 of 5, Codabar, Code 39, Code 128)/yes

Lab can control analyzer from remote computer

yes

Instrument can diagnose its own malfunctions

yes (operator intervention required to order parts)

System malfunctions can be diagnosed via remote monitoring

yes

UPS backup power supply

yes

Data-management capability/LIS or EHR systems interfaced

onboard/SCC, Meditech, Cerner, Epic, Sunquest, more

LIS interface provided/Bidirectional interface capability

yes (incl. in instrument price)/yes (broadcast download and host query)

Modem servicing provided/Service engineer on-site response time

yes/< 8 hrs.

Mean time between failures

avg. 152 days per module (displays error codes for troubleshooting)

Average scheduled maintenance time by lab personnel

daily: 4–5 min.; weekly: 20 min.; monthly: 25 min.

Maintenance records kept onboard for user/vendor

yes/yes (both include audit trail of who replaced parts)

Maintenance training demonstration module onboard

yes

Training included with purchase/Avg. time for basic user training

yes (4 training slots)/~5 days (at customer and vendor sites)

Advanced operator training/Extra charge for follow-up or advanced training

yes (at vendor site)/yes (cost varies by contract)

Warranty provided/Cost of annual service contract (24 h/7 d)

yes (1 year)/configuration dependent

Distinguishing features (supplied by company)

high reagent onboard and calibration stability; no reagent prep; on-the-fly loading; broad test menu: > 180 assays on one integrated platform

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