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Tuesday, October 20, 2026, 11 AM-12 PM ET
Hear experts review the biological and clinical significance of the HER2 expression continuum in breast tissue, providing a clearer understanding of how these variations might impact diagnosis, and discuss the emerging importance of documenting HER2-low and HER2-ultralow categories using a validated IHC assay.

Webinar presenters Keith Wharton, MD, PhD, Global Medical Affairs Leader–Pathology, Roche Diagnostics Solutions, and Hannah Y. Wen, MD, PhD, Director, Breast Pathology Fellowship, Associate Team Leader, Breast Pathology Team, Attending Pathologist, Memorial Sloan Kettering Cancer Center

CAP TODAY does not endorse any of the products or services named within. The webinar is made possible by a special educational grant from Roche.

Moderated by: Bob McGonnagle, Publisher, CAP TODAY

Thursday, October 29, 2026, 1 PM-2 PM ET
Hear an expert discuss the evolving role of PD-L1 testing in HNSCC and ovarian cancer.

Webinar presenter Georgios Deftereos, MD, Professor of Pathology, Associate Director of the Clinical Cancer Genomics Laboratory, Director of Molecular Cytopathology, University of California, San Francisco

CAP TODAY does not endorse any of the products or services named within. The webinar is made possible by a special educational grant from Agilent.

Moderated by: Bob McGonnagle, Publisher, CAP TODAY

Tuesday, November 3, 2026, 1 PM-2 PM ET
Hear an expert discuss the challenges of detecting NRG1 fusions and how RNA-based testing can support more comprehensive fusion identification in clinical practice.

Webinar presenter Benjamin Weinberg, MD, Associate Professor of Medicine and Attending Physician
specializing in gastrointestinal medical oncology

CAP TODAY does not endorse any of the products or services named within. The webinar is made possible by a special educational grant from Diaceutics.

Moderated by: Bob McGonnagle, Publisher, CAP TODAY

Tuesday, November 10, 2026, 1 PM-2 PM ET
Join us for a session to help improve diagnostic accuracy in your practice when scoring HER2 IHC 0 with faint, incomplete membrane staining in ≤10% of tumor cells vs IHC 0 with no membrane staining detected in patients with mBC.

Webinar presenter Jeffrey Gregg, MD, University of Nevada

CAP TODAY does not endorse any of the products or services named within. This program is being sponsored by Daiichi Sankyo, Inc. and AstraZeneca. The speaker is being compensated for the presentation. The program is not CME accredited and may not be used for CME accreditation.

Moderated by: Bob McGonnagle, Publisher, CAP TODAY

Monday, November 16, 2026, 12:30 PM-2 PM ET
Hear experts discuss a multidisciplinary approach to oncopathology for HER2
assessments for solid tumors in the absence of a companion diagnostic.

Webinar presenters Funda Meric-Bernstam, MD, Chair, Department of Investigational Cancer Therapeutics Medical Director, Institute for Personalized Cancer Therapy, The University of Texas MD Anderson Cancer Center, Houston, Texas, and Emina E. Torlakovic, MD, PhD, College of Medicine, University of Saskatchewan, Canadian Biomarker Quality Assurance, Saskatoon, Saskatchewan, Canada, and Carol Cheung, MD, PhD, JD, FRCPC, Deputy Director, Canadian Biomarker Quality, Assurance—Programme canadien d’assurance de la qualité des biomarqueurs

CAP TODAY does not endorse any of the products or services named within. This program is being sponsored by Daiichi Sankyo, Inc. and AstraZeneca. The speaker is being compensated for the presentation. The program is not CME accredited and may not be used for CME accreditation.

Moderated by: Bob McGonnagle, Publisher, CAP TODAY

Subspecialties

Interactive Product Guides

Product Spotlight

Sysmex America

UN-Series Automated Urinalysis Solution (UN-2000, UN-3000, UN-9000)

Company

Sysmex America

Name of urinalysis instrument

UN-Series Automated Urinalysis Solution (UN-2000, UN-3000, UN-9000)

Contact

Pinak Patel  

Email

patelpi@sysmex.com

City, State

Lincolnshire, IL

Phone

888-879-7639  

Website

http://www.sysmex.com/us

Type of instrument

urine chemistry and microscopy/sediment combined

Instrument list price

based on configuration (avail. via purchase or lease)

First year instrument sold in the U.S.

UN-2000: 2019; UN-3000 and UN-9000: 2020

Approximate No. of units in clinical use in the U.S./outside the U.S.

>600/— (in Canada)

Foreign countries where company markets instrument

Canada

Country where instrument is designed/manufactured

Japan/Japan

Human languages (other than English) supported

—

Intended urine sample volume per day

>80

Dimensions (H×W×D)

varies based on configuration

Weight fully loaded with reagents/without reagents

both vary based on configuration

Power requirements

varies based on configuration

Mean time between failure of instrument

90 days

Events that cause instrument to lock or stop analysis

user ID failure, consumables replacement/expiration

• Urine chemistry tests available on instrument in the U.S.

bilirubin (0.5–2.7 mg/dL), red blood cells (trace levels), hemoglobin (0.013–0.3 mg/dL), glucose (36–820 mg/dL), ketone (3.6–156 mg/dL), leukocyte esterase (6–91 cells/µL), nitrite (positive/negative), pH (5.3–8.7), protein (10.8–1,000 mg/dL), specific gravity (1.000–1.099), urobilinogen (0.24–6.24 mg/dL)

• Color compensation pad included/Flagging thresholds customizable

yes/yes

• Test strip configuration

cartridge

• Calibration required after each test strip lot No. change

yes

• Frequency of customer-performed calibration/Form of calibration

with every new lot No. of Novus cassette loaded or same lot No. loaded and calibration is > 24 hours old/liquid

• How results are displayed for urine chemistry

semiquantitative

• Specific gravity correction for protein/glucose

no/no

• Microscopy/sediment technology

flow cytometry with fluorescent stain

• Microscopy/sediment analysis parameters

flagged and qualitative: pathological casts, crystals, yeast-like cells, mucus, sperm; qualitative and quantitative: RBCs; quantitative:  WBCs, epithelial cells, bacteria, casts

• Flagging thresholds customizable

yes

• Instrument eliminates amorphous crystal interference before sample analysis

yes

• How results are displayed for microscopy/sediment

numeric values or scattergrams

• Reporting format customizable

yes

• No. of results that can be held in internal memory

100,000 sample results (in the urinalysis data manager)/ 2 concentrations × 3 lots (120 plots/lot) for control results

Reagent shelf life/storage temp. for unopened containers of calibrator

—

Reagent shelf life/storage temp. for opened containers of calibrator

—

Reagent shelf life/storage temp. for unopened containers of control reagent

—/2–8°C

Reagent shelf life/storage temp. for opened containers of control reagent

—

Reagent barcode-reading capability

yes, for all tests (can read Code 39, Code 128, more)

How often quality control samples are run

daily

Sample throughput per hour/Time to first result for chemistry

240/—

Sample throughput per hour/Time to first result for microscopy/sediment

varies based on configuration/—

Analyzer has stat mode

yes (min. sample vol., 1.6 mL for microscopy/sediment)

FDA approved for body fluid analysis

no

Sample dilutions required for urinalysis/body fluid analysis

no/not applicable

Minimum width of sample tube/Minimum length of sample tube

16 mm/95 mm

Conditions or substances that prevent a sample from being run

—

Means of sample ID entry

barcode scan, manual entry, worklist download from host, RFID for authentic entry of cassette lot

Built-in liquid-level sensing for samples

yes

Information that can be barcode scanned on instrument

operator identifier, specimen identifier, reagent lot No.

Compatible with laboratory automation systems

yes (Siemens Aptio, Abbott Accelerator a3600)

How LOINC codes for results are made available

website, e-mail query

Software includes reflex testing/cross-check functionality

yes/yes

Instrument automatically generates consolidated report*

yes

Instrument archives patient data

yes (patient demographics, test results, sample ID)

Instrument connections to transfer information

data-management system that connects to LIS or EHR, or directly to LIS or EHR

Interface standards or formats supported

ASTM 1394-91, ASTM 1381, HL7 version 3

Bidirectional interface

yes, to other companies’ LISs and EHRs 

Test results can be transmitted to LIS as soon as tests completed

yes

Connection to LIS/EHR to upload patient and QC results

LIS and EHR: hospital network

Information included in transmission to data-management system

device unique identifier, operator ID, patient ID, specimen ID, result, QC identifier

Training included with instrument purchase

yes (7 hours of virtual instructor-led training at customer site)

Approximate scheduled maintenance time required

20 min. daily; 10 min. weekly (maintenance records kept onboard instrument)

Onboard diagnostics for troubleshooting

yes (can perform diagnostics via remote access) 

Provide list of client sites to potential customers on request

yes (partial list of comparable sites with no restrictions regarding its use)

Distinguishing instrument features (supplied by company) 

combines urine chemistry, fluorescence flow cytometry, and digital image analysis for rapid urine screening; BeyondCare quality monitor for urinalysis provides a streamlined and automated QC experience

*chemistry and microscopy results in one report; Note: a dash in lieu of an answer means company did not answer; question or question is not applicable

†modular systems: UN-2000, two modules; UN-3000, three modules; UN-9000, four or more modules

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DxU Iris Workcell: DxU 850 Iris, DxU 840 Iris
DxU Microscopy Series: DxU 850m Iris, DxU 840m Iris
AUA-450 Clinical Chemistry Analyzer
Clinitek Novus Automated Urine Chemistry Analyzer