April 2014—Horizon Discovery signed a worldwide distribution agreement with Haplogen in which customers can access, directly from Horizon, Haplogen’s Haploid Gene Trap Mutant Collection of isogenic human cell lines deficient for the expression of single genes. This is the first time Horizon will distribute another company’s products.
Haploid cellular models offer a biologically relevant system for in vitro genetic analyses of molecular, cellular, and developmental events in various cell lineages. The gene trap mutant collection is the largest haploid cell line bank available, comprising more than 9,400 mutant clones and affecting more than 3,700 human genes and 1,600 inducible clones covering 1,100 genes.
Horizon also has the first products and services from its new Genassist range of gene editing kits and reagents. Genassist offers off-the-shelf reagents for using CRISPR editing technology and a kit combination of these reagents so customers can generate their own CRISPR-ready cell lines that constitutively express Cas9-nickase. Using such cell lines provide a quick start for customers, enabling them to make modifications to the cell line more efficiently than if they were starting fresh each time. Horizon is also launching a service for the design, manufacture, and validation of CRISPR RNA guides to maximize the likelihood that gene editing will occur as expected.
Horizon Discovery, +44 (0) 1223 655 580