Webinars and Sponsored Roundtables — Register Now

Tuesday, April 28, 2026, 12:00 PM–1:00 PM ET
Discover how next-day comprehensive genomic profiling (CGP) is possible with the Oncomine Comprehensive Assay Plus on the Genexus System—delivering both speed and accuracy.

Webinar presenters Jane Bayani, MHSc, PhD, Assistant Professor and Co-Director, Diagnostic Development, Ontario Institute for Cancer Research, Canada, and Nicola Normanno, MD, Scientific Director, IRCCS Romagnolo Institute for the Study of Tumors, Italy, and Morten Grauslund, PhD, Molecular Biologist, Department of Pathology, Rigshospitalet/Copenhagen University Hospital, Copenhagen, Denmark.

Moderated by: Bob McGonnagle, Publisher, CAP TODAY

CAP TODAY does not endorse any of the products or services named within. The webinar is made possible by a special educational grant from Thermo Fisher Scientific. For Research Use Only. Not for use in diagnostic applications. 

Thursday, April 30, 2026, 11:00 AM–12:00 PM ET
Hear an expert discuss how Memorial Sloan Kettering Cancer Center (MSKCC) is utilizing
the oncoReveal® Nexus 21-gene panel to redefine turnaround time and actionable insights
in cancer care. Dr. Ewalt shares a perceptive look at the clinical need for rapid, front-line NGS sequencing, and how a unique, purpose built targeted NGS panel (Pillar Biosciences’ oncoReveal Nexus 21 gene Panel) was developed, validated and implemented clinically by Memorial Sloan Kettering Cancer Center (MSK-REACT) to complement their current comprehensive genomic profiling (CGP) approach.

Webinar presenter Mark Ewalt, MD, Associate Medical Director for Laboratory Operations for Diagnostic Molecular Pathology in the Molecular Diagnostics Service, Department of Pathology and Laboratory Medicine, MSKCC.

Moderated by: Bob McGonnagle, Publisher, CAP TODAY

CAP TODAY does not endorse any of the products or services named within. The webinar is made possible by a special educational grant from Pillar Biosciences.

Thursday, May 28, 2026, 1:00–2:00 PM ET
This session is designed to improve understanding and application of recent updates to synoptic pathology reporting protocols such as the latest Reporting Template for Reporting Results of Biomarker Testing of Specimens from Patients with Carcinoma of the Breast. These changes reflect evolving clinical guidelines that directly influence diagnostic accuracy and treatment selection in breast cancer care.

Webinar presenters Thaer Khoury, MD, FCAP, Chair, Pathology and Laboratory Medicine, Roswell Park Comprehensive Cancer Cente, and Colin Murphy,  CEO of mTuitive.

Moderated by: Bob McGonnagle, Publisher, CAP TODAY

Subspecialties

Interactive Product Guides

Product Spotlight

Siemens Healthineers

CS-2500 System

Company

Siemens Healthineers

Instrument name

CS-2500 System

Contact

Laura Oversmith  

City State

Tarrytown, NY

Phone

914-631-8000

First year sold

2016

Website

https://siemens-healthineers.us.com

List price/Model type

$155, 000/benchtop

Dimensions (H × W × D)/Weight/Instrument footprint

27 × 30.6 × 35.2 in./242.5 lbs./7.5 sq. ft.

No. of units in clinical use in U.S./Outside U.S.

>500/>2, 000 (worldwide)

Composition of installs: Hospital lab/Reference lab/Other

Targeted daily, monthly, annual test volume

daily: 25–300

Operational type

continuous random access

Country where analyzer designed/Manufactured

Japan/Japan

Company manufactures instrument

no (manufactured by Sysmex)

FDA-approved clotting-based tests

PT, APTT, fibrinogen, factors II, V, VII, VIII, IX, X, XI and XII, protein C, lupus screen, lupus confirm, factor V Leiden, thrombin time, batroxobin time

FDA-approved chromogenic tests

antithrombin, protein C, Innovance free protein S antigen, plasminogen, Innovance heparin, factor VIII chromogenic, alpha-2-antiplasmin, Innovance anti-Xa

FDA-approved immunologic tests

Innovance VWF activity, VWF antigen, Innovance D-dimer

Other FDA-approved tests

User-defined tests in clinical use

platelet aggregation RUO, factor XIII chromogenic RUO

Tests in development or awaiting FDA 510(k) clearance

Methodologies supported

clot detection, optical; turbidimetric; chromogenic; immunologic (immunoturbidimetric)

Number of different measured assays onboard simultaneously

60

Number of different assays programmed and calib. at one time

60

No. of user-definable (open) channels/No. active simultaneously

80, 000/60

Factor assays require manual manipulation or dilutions

Test throughput per hour/Assay run time

180 (2 tests in throughput)/1–10 min. (avg. 5 min.)

Design of sample-handling system

10-tube position sample rack with a maximum of 5 × racks

Operates on whole blood or spun plasma

spun plasma

Reagent type

self-contained single-use vials; open reagent system (liquid, lyophilized [reconstituted manually])

Reagent barcode-reading capability

yes, for all tests

No. of reagent containers held onboard/Reagents ready to use

45/variable (reagent specific)

Reagent lot tracking/Reagent inventory/Reagents refrigerated onboard

yes/yes/yes (10°C ± 2°C)

Reagents, consumables loaded without interrupting testing

yes (reagents and consumables)

Instrument uses proprietary or third-party reagents

user’s option (same capabilities when third-party reagents used)

Maximum time same lot number of reagents can be used

18 months

Walkaway capability/Walkaway duration

yes/50 specimens or up to 500 tests

Min.–max. specimen volume that can be aspirated at one time

5–500 µL

Min. sample volume required for PT/PTT/Factor VIII activity

50 µL/50 µL/5 µL (standard)

Types of disposables used

reaction cuvettes, CA clean I, CA clean II

Primary tube sampling supported/Pierces caps on primary tubes

yes/yes

Accommodates most standard tube sizes/Nonstandard sizes

yes/yes

Sample barcode-reading capability/Autodiscrimination

yes (Interleaved 2 of 5, Code 39, Code 128)/yes

Auto tracks product volume/Measures number of tests remaining

yes/yes

Short sample detection

yes

Clot detection as preanalytical variable in plasma sample

yes

Auto detects adequate reagents for aspiration or analysis

yes (aspiration and analysis)

Detection or quantitation for hemolysis, turbidity, icterus, lipemia 

detection and quantitation for hemolysis, turbidity, icterus, lipemia

Dilutes patient samples onboard

yes

Automatic rerun capability/Auto reflex testing capability

yes/yes

Lag time during which hypercoagulable sample not detected

yes (PT: 7 seconds; PTT: 15 seconds)

User can adjust reagent volumes/Sample volumes

yes/yes

User can adjust No. of reagents/Sources of reagents

yes/yes

User can adjust incubation times/Reading times

yes/yes

Autocalibration/Calibrants stored onboard

yes/yes

Multipoint calibration supported/Recommended frequency

yes/6 months, per regulatory guidelines 

• PT alone

<5 minutes/180 specimens

• PT, PTT

<5 minutes/90 specimens

• Fibrinogen

<5 minutes/180 specimens

• Factor VIII activity assay

<5 minutes/—

• D-dimer

<5 minutes/90 specimens

Time delay from ordering stat to aspiration of sample

<1 minute

How labs get LOINC codes for results

website

Onboard real-time QC/Onboard software capability to review QC

yes/yes

Information that can be barcode-scanned on instrument

operator identifier, specimen identifier, reagent lot No., reagent vial ID, reagent expiry

Compatible with laboratory automation systems

no

Data-management capability/LIS or EHR systems interfaced

onboard/most major vendors

Interface supplied by instrument vendor

contract dependent

Results transferred to LIS as soon as test time complete

yes

Bidirectional interface capability

yes (host query)

Remote servicing provided/UPS backup power supply

yes/yes

Instrument connections to transfer information

data-management system, which in turn connects to LIS or EHR; directly to LIS or EHR; directly to lab automation system; commercial middleware (most major companies)

Interface standards supported

ASTM 1394-91, ASTM 1381, HL7, CA-1000 protocol, CA-1500 protocol

Information transferred to data-management software

device unique identifier, operator ID, patient ID, specimen ID, result, QC identifier, PSI checks

Avg. time for basic user training

2 days (at customer site), some self-study virtual training required

Approximate scheduled maintenance time

daily: <5 minutes; weekly: <10 minutes; monthly: <10 minutes

Maintenance records kept onboard

yes

Warranty with purchase/Annual service contract cost (24/7)

yes/— (cost dependent on contract)

Distinguishing features (supplied by company)

simultaneous multiwavelength detection and PSI technology designed to ensure high-quality first-run results; user-friendly software on Windows 10; tilted reagent vials for efficiency; for multisite patient monitoring, with sample result traceability for in-depth audit capabilities

More products
in this guide

PAP-8E Platelet Aggregometer
Optical Aggregation Systems Models 490 4+ | 490 4+4
Whole Blood Optical Lumi-Aggregation System 700-2 | 700-4
Quantra Hemostasis Analyzer
Sysmex CA-600 Series Systems: CA-620 | CA-660
Sysmex CN-3000
Sysmex CN-6000
Sysmex CS-2500 System
Sysmex CS-5100 System
ACL TOP 550 CTS
ACL TOP 750 Series
ACL TOP 770/770s
ACL TOP 770 LAS
ACL TOP 970 CL