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Liquid biopsy workflow for NGS system, 9/16

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September 2016—Qiagen launched a liquid biopsy workflow for clinical cancer research using its GeneReader NGS System for next-generation sequencing. The Actionable Insights Tumor Panel is a sample-to-insight solution for noninvasive liquid biopsies and formalin-fixed, paraffin-embedded tissue samples. The panel is now optimized for NGS analysis of blood plasma using automated Qiagen sample technologies for circulating cell-free DNA, enabling tumor characterization and monitoring of cancer resistance markers as a complement to initial tissue biopsies.

The liquid biopsy workflow includes the panel and liquid biopsy sample technologies for plasma plus specialized software and bioinformatics. The solution creates a workflow for testing plasma samples when FFPE tissue is not available or preferred. The NGS panel has demonstrated highest sensitivity of one percent in analyzing cancer variants in liquid biopsy clinical samples and Horizon control material. Bioinformatics analysis and interpretation are integrated into the GeneReader NGS System workflow, powered by the company’s Clinical Insight, which interacts with curated and proprietary knowledge databases to enable efficient interpretation of NGS variants for actionable insights.

Qiagen , 240-686-7700

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