CAP TODAY Pathology/Laboratory Medicine/Laboratory Management
March 2015—Illumina launched the MiSeq FGx Forensic Genomics System, a fully validated forensic next-generation sequencing system that simultaneously interrogates short tandem repeats and other valuable genetic markers, including single nucleotide polymorphisms, to provide informative DNA profiles. The system enables robust analysis of a range of genetic markers in a single workflow.
Designed in collaboration with leading forensic genomics and human identification experts, the MiSeq FGx system leverages Illumina’s sequencing by synthesis chemistry. Compatible with existing DNA databases, including the Combined DNA Index System, the system can be used for criminal casework and in other situations such as mass disasters, missing persons, and unidentified human remains. Dense data sets, with powerful population statistics, can be generated for highly compromised samples, such as DNA degraded to less than 100 base pairs. The technology can also provide SNP-based physical information about biogeographical ancestry and visible, physical traits, including hair and eye color.
In addition to the MiSeq FGx DNA sequencer, the system includes the ForenSeq DNA Signature Prep Kit and ForenSeq Universal Analysis Software. This sample-to-answer solution aims to enable labs to maximize the information derived from a sample, eliminating the need for multiple rounds of partial, iterative testing. Using low quantities of DNA (< 1 ng), the prep kit amplifies forensic targets via a streamlined workflow that maximizes the genetic information recovered from challenging samples and minimizes the potential for errors. Intuitive ForenSeq software facilitates the complete run setup, sample management, and analysis, and delivers reports on a standalone, dedicated server.
Illumina, 858-202-4500