CAP TODAY Pathology/Laboratory Medicine/Laboratory Management
April 13, 2020—Oxford Gene Technology has added detection capabilities for translocations and difficult-to-sequence partial tandem duplications in its MyPanel customizable SureSeq NGS panels. The expanded content enables OGT SureSeq MyPanel custom panels to be customized to include the BCR-ABL gene fusion, resulting from a translocation of chromosome 9 and 22 generating the Philadelphia chromosome. OGT’s Interpret software can detect translocation events in the genome and agnostically screen for split reads. Partial tandem duplications in acute myeloid leukemia can also be detected, including those in the KMT2A (MLL) gene. Researchers can choose to customize content and include KMT2A-PTD detection.