Webinars and Sponsored Roundtables — Register Now
Tuesday, April 28, 2026, 12:00 PM–1:00 PM ET
Discover how next-day comprehensive genomic profiling (CGP) is possible with the Oncomine Comprehensive Assay Plus on the Genexus System—delivering both speed and accuracy.
Webinar presenters Jane Bayani, MHSc, PhD, Assistant Professor and Co-Director, Diagnostic Development, Ontario Institute for Cancer Research, Canada, and Nicola Normanno, MD, Scientific Director, IRCCS Romagnolo Institute for the Study of Tumors, Italy, and Morten Grauslund, PhD, Molecular Biologist, Department of Pathology, Rigshospitalet/Copenhagen University Hospital, Copenhagen, Denmark.
Moderated by: Bob McGonnagle, Publisher, CAP TODAY
CAP TODAY does not endorse any of the products or services named within. The webinar is made possible by a special educational grant from Thermo Fisher Scientific. For Research Use Only. Not for use in diagnostic applications.
Thursday, April 30, 2026, 11:00 AM–12:00 PM ET
Hear an expert discuss how Memorial Sloan Kettering Cancer Center (MSKCC) is utilizing
the oncoReveal® Nexus 21-gene panel to redefine turnaround time and actionable insights
in cancer care. Dr. Ewalt shares a perceptive look at the clinical need for rapid, front-line NGS sequencing, and how a unique, purpose built targeted NGS panel (Pillar Biosciences’ oncoReveal Nexus 21 gene Panel) was developed, validated and implemented clinically by Memorial Sloan Kettering Cancer Center (MSK-REACT) to complement their current comprehensive genomic profiling (CGP) approach.
Webinar presenter Mark Ewalt, MD, Associate Medical Director for Laboratory Operations for Diagnostic Molecular Pathology in the Molecular Diagnostics Service, Department of Pathology and Laboratory Medicine, MSKCC.
Moderated by: Bob McGonnagle, Publisher, CAP TODAY
CAP TODAY does not endorse any of the products or services named within. The webinar is made possible by a special educational grant from Pillar Biosciences.
Thursday, May 28, 2026, 1:00–2:00 PM ET
This session is designed to improve understanding and application of recent updates to synoptic pathology reporting protocols such as the latest Reporting Template for Reporting Results of Biomarker Testing of Specimens from Patients with Carcinoma of the Breast. These changes reflect evolving clinical guidelines that directly influence diagnostic accuracy and treatment selection in breast cancer care.
Webinar presenters Thaer Khoury, MD, FCAP, Chair, Pathology and Laboratory Medicine, Roswell Park Comprehensive Cancer Cente, and Colin Murphy, CEO of mTuitive.
Moderated by: Bob McGonnagle, Publisher, CAP TODAY
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Roche Diagnostics
| Company | Roche Diagnostics |
|---|---|
| Name of instrument | cobas e 411 |
| City, State | Indianapolis, IN |
| Phone | 800-428-5074 |
| Website | |
| Type of instrument | immunoassay |
| Operational type/Model type | random access, continuous random access/benchtop |
| List price/First year sold in U.S. | —/2008 |
| Targeted hospital bed size/Targeted | < 100/daily: < 200; monthly: < 40, 000; annual: < 500, 000 |
| Company manufactures instrument | no (manufactured by Hitachi High-Technologies) |
| Other models in this family of analyzers | — |
| No. of units in clinical use in U.S./Outside U.S. (countries) | > 800/> 10, 000 (> 50 countries) |
| Dimensions (H × W × D)/Instrument footprint | disk: 31.4 × 47.2 × 28.7 in./9.4 sq. ft.; |
| Weight empty/Weight fully loaded | rack: 31.4 × 67 × 37.4 in./17.4 sq. ft. |
| No. of different measured assays onboard simultaneously | disk: 397 lbs./397 lbs.; rack: 551 lbs./551 lbs. |
| No. of user-definable (open chemistry) channels | 18 (18 can be run and calibrated at one time) |
| Test throughput per hour/Assay run time | 0 |
| No. of direct ion-selective electrode channels | 86 (86 tests in throughput)/9–27 min. (avg. 18 min.) |
| Detection methods | — |
| • Ion-selective electrode | — |
| • Basic metabolic panel | — |
| • Complete metabolic panel | — |
| Typical time delay from ordering stat test until aspiration of sample | — |
| Fully automated microplate immunoassay system | no |
| Methodologies supported | electrochemiluminescence |
| Separation methodologies | magnetic particle |
| Stat time until completion of a ß-hCG test | ~10 min. |
| Stat time until completion of a cTn test | ~10 min. |
| • Typical time delay from test order to aspiration of sample | < 1 min. |
| Approximate No. of tests per reagent set/Reagent type | 100–200/self-contained multiuse |
| Reagents refrigerated onboard/Reagents ready to use | no (20ϒ ±3ϒC)/yes |
| Reagent lot tracking/Reagent inventory | yes/yes |
| Reagent form/Reagents barcoded | liquid chemistry (closed reagent system)/yes |
| Separate reagent pack for each specimen/for each test run | no/no |
| Walkaway capability/Walkaway duration | yes/30–60 min. or 30 specimens (disk), 75 specimens (rack) or 2, 000–3, 000 tests/assays |
| Design of sample-handling system | disk: ring; rack: rack |
| Uses washable cuvettes/Uses disposable cuvettes | no/yes (can store up to 360 assay tips, 180 assay cups) |
| Min.–max. sample volume that can be aspirated at one time | 10–50 µL |
| Min. reaction volume/Min. specimen volume/Min. dead volume | 100 µL/10 µL/100 µL |
| Dedicated pediatric sample cup | yes (dead volume: 50 µL) |
| Primary tube sampling | yes |
| Accommodates most standard tube sizes/Accepts nonstandard tube sizes | yes/yes (12 × 100 mm) |
| Pierces caps on primary tubes | no |
| Protects against probe collision | yes |
| Detects clots/liquid level/short sample | yes/yes/yes |
| Detection or quantitation for hemolysis, icterus, lipemia, clots | detection for clots; hemolysis, icterus, lipemia not available |
| Dilutes patient samples onboard/Susceptibility to carryover | yes (can be programmed to perform sample dilutions prior to analysis)/0 (uses disposable tips) |
| Automatic rerun capability | yes |
| Sample volume can be concentrated to rerun out-of-linear-range low results | yes |
| Analyzer requires dedicated water supply | no (3 L consumption for 250 tests) |
| Autocalibration/Multipoint calibration supported | yes (calibrants are not stored onboard)/yes (recommended avg. frequency: 28 days) |
| Typical calibration frequency for ISE/therapeutic drugs/drugs of abuse/general chemistries/immunoassays | —/—/—/—/28 days |
| Automatic programmable start/Automatic programmable shutdown | yes (4 min. avg. start-up time)/yes |
| Onboard real-time QC/Onboard software capability to review QC | yes/yes |
| Supports multiple QC lot numbers per analyte | yes |
| Waste management | automated collection onboard instrument |
| Sample barcode-reading capability/Autodiscrimination | yes (Interleaved 2 of 5, Codabar, Code 39, Code 128, PDF417)/yes |
| Lab can control analyzer from remote computer | no |
| Instrument can diagnose its own malfunctions | yes (operator intervention required to order parts) |
| System malfunctions can be diagnosed via remote monitoring | yes |
| UPS backup power supply | yes |
| Data-management capability/LIS or EHR systems interfaced | onboard/SCC Soft Computer, Meditech, Cerner, Epic, Sunquest, more |
| LIS interface provided/Bidirectional interface capability | yes (included in instrument price)/yes (broadcast download and host query) |
| Modem servicing provided/Service engineer on-site response time | yes/< 24 hrs. |
| Mean time between failures | 368 days (displays error codes for troubleshooting) |
| Average scheduled maintenance time by lab personnel | daily: 5 min.; weekly: 6 min.; monthly: 11 min. |
| Maintenance records kept onboard for user/vendor | yes (includes audit trail of who replaced parts)/yes (includes audit trail of who replaced parts) |
| Maintenance training demonstration module onboard | yes |
| Training included with purchase/Avg. time for basic user training | yes (1 training slot)/1 week (at both vendor and customer sites) |
| Advanced operator training/Extra charge for follow-up or advanced training | yes (at vendor site)/yes |
| Warranty provided/Cost of annual service contract (24 h/7 d) | yes (1 year)/configuration dependent |
| Distinguishing features (supplied by company) | drives lab efficiency with standardized instrumentation, reference ranges, consumables, and usage; minimizes downtime with industry-leading engineering and service; 325-day mean time between repair visits (average); speeds up turnaround time for high-volume stat assays |