AMP case report: NGS of a rare metastatic bladder adenocarcinoma

in 2019 Issues, AMP Case Reports, ARTICLES, September 2019

Test yourself

Here are three questions taken from the case report.
Answers

Answers are online at www.amp.org/casereports and will be published next month in CAP TODAY.

1. What immunohistochemical stain is best used for differentiating metastatic colonic adenocarcinoma from bladder adenocarcinoma?
a. CK20
b.  CDX2
c. CK7
d.  β-catenin

2. What role does the CyclinD1 protein play in normal cell function?
a. Cell-cell junction protein
b. Apoptosis pathway protein
c. Cell cycle regulator protein
d. Cell surface receptor protein

3. Which of the following genes has a high rate of pathogenic mutation in urothelial
carcinoma?
a.  KRAS
b. TP53
c. APC
d. CCND1

1. What immunohistochemical stain is best used for differentiating metastatic colonic adenocarcinoma from bladder adenocarcinoma?
a. CK20
b.  CDX2
c. CK7
d.  β-catenin

2. What role does the CyclinD1 protein play in normal cell function?
a. Cell-cell junction protein
b. Apoptosis pathway protein
c. Cell cycle regulator protein
d. Cell surface receptor protein

3. Which of the following genes has a high rate of pathogenic mutation in urothelial
carcinoma?
a.  KRAS
b. TP53
c. APC
d. CCND1

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