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Webinars and Sponsored Roundtables — Register Now

Tuesday, April 28, 2026, 12:00 PM–1:00 PM ET
Discover how next-day comprehensive genomic profiling (CGP) is possible with the Oncomine Comprehensive Assay Plus on the Genexus System—delivering both speed and accuracy.

Webinar presenters Jane Bayani, MHSc, PhD, Assistant Professor and Co-Director, Diagnostic Development, Ontario Institute for Cancer Research, Canada, and Nicola Normanno, MD, Scientific Director, IRCCS Romagnolo Institute for the Study of Tumors, Italy, and Morten Grauslund, PhD, Molecular Biologist, Department of Pathology, Rigshospitalet/Copenhagen University Hospital, Copenhagen, Denmark.

Moderated by: Bob McGonnagle, Publisher, CAP TODAY

CAP TODAY does not endorse any of the products or services named within. The webinar is made possible by a special educational grant from Thermo Fisher Scientific. For Research Use Only. Not for use in diagnostic applications. 

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Thursday, April 30, 2026, 11:00 AM–12:00 PM ET
Hear an expert discuss how Memorial Sloan Kettering Cancer Center (MSKCC) is utilizing
the oncoReveal® Nexus 21-gene panel to redefine turnaround time and actionable insights
in cancer care. Dr. Ewalt shares a perceptive look at the clinical need for rapid, front-line NGS sequencing, and how a unique, purpose built targeted NGS panel (Pillar Biosciences’ oncoReveal Nexus 21 gene Panel) was developed, validated and implemented clinically by Memorial Sloan Kettering Cancer Center (MSK-REACT) to complement their current comprehensive genomic profiling (CGP) approach.

Webinar presenter Mark Ewalt, MD, Associate Medical Director for Laboratory Operations for Diagnostic Molecular Pathology in the Molecular Diagnostics Service, Department of Pathology and Laboratory Medicine, MSKCC.

Moderated by: Bob McGonnagle, Publisher, CAP TODAY

CAP TODAY does not endorse any of the products or services named within. The webinar is made possible by a special educational grant from Pillar Biosciences.

Register Now

Thursday, May 28, 2026, 1:00–2:00 PM ET
This session is designed to improve understanding and application of recent updates to synoptic pathology reporting protocols such as the latest Reporting Template for Reporting Results of Biomarker Testing of Specimens from Patients with Carcinoma of the Breast. These changes reflect evolving clinical guidelines that directly influence diagnostic accuracy and treatment selection in breast cancer care.

Webinar presenters Thaer Khoury, MD, FCAP, Chair, Pathology and Laboratory Medicine, Roswell Park Comprehensive Cancer Cente, and Colin Murphy,  CEO of mTuitive.

Moderated by: Bob McGonnagle, Publisher, CAP TODAY

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Subspecialties

Interactive Product Guides

Abstracts

Clinical pathology selected abstracts

November 2024—Pathology training programs are meant to prepare trainees for the workforce by imparting medical knowledge and developing skills in diagnostic interpretation in anatomic pathology. Yet transitioning to the workforce can be challenging for some new graduates. To address this, many training programs have begun teaching management and leadership skills that are required on the job. In addition, the College of American Pathologists New in Practice Committee developed online educational material to provide practical advice for those starting their pathology careers.

Anatomic pathology selected abstracts

November 2024—Inactivating alterations in switch/sucrose nonfermentable (SWI/SNF) chromatin remodeling complex subunits have been described in multiple tumor types. Recent studies focused on SMARC subunits of this complex to explain their relationship with tumor characteristics and therapeutic opportunities. Pancreatic cancer with these alterations has not been well studied, although isolated cases of undifferentiated carcinomas have been reported.

Molecular pathology selected abstracts

November 2024—Many people with an intellectual disability do not receive a molecular diagnosis following genetic testing. While 1,427 genes have been confidently identified as etiological for an intellectual disability (ID), all but nine of them are protein coding. To identify noncoding etiologies of ID, the authors conducted a genetic association analysis using whole genome sequencing data on 77,539 participants in the 100,000 Genomes Project. The study included 29,741 probands and 4,782 affected relatives assigned by expert clinicians to one or more of 220 specific disease classes encompassing a wide range of pathologies.

Clinical pathology selected abstracts

October 2024—Exposure to lead is associated with irreversible adverse effects on fetal and neonatal development. Because no reliable threshold exists for determining the impact of lead exposure on children, the CDC began using the term blood lead reference values to identify children with higher blood lead levels (BLLs). Limiting exposure to lead is critical to ensuring that vulnerable populations, such as fetuses, neonates, and children, are not at risk for adverse neurodevelopmental outcomes. Lead and inorganic lead compounds are classified as carcinogens, while such metals as mercury and cadmium are considered neurotoxicants. Studies have shown a significant correlation between post-transfusion BLLs in infants and lead levels in RBC units.

Anatomic pathology selected abstracts

October 2024—Screening for colorectal cancers can involve assessing mismatch repair deficiency or microsatellite instability to identify people with Lynch syndrome, the most common hereditary syndrome causing colorectal cancer. Advanced adenomas are considered immediate precursor lesions of colorectal cancer. The authors conducted a study in which they investigated the relevance of microsatellite instability screening of advanced adenomas for Lynch syndrome in population screening. They selected advanced adenomas (n=1,572) from the Dutch colorectal cancer population screening program. All were reviewed and met one or more of the following criteria: tubulovillous (n=848, 54 percent) or villous (n=118, 7.5 percent) adenoma, diameter of 1 cm or more (n=1,286, 82 percent), or high-grade dysplasia (n=176, 11 percent).

Molecular pathology selected abstracts

October 2024—Huntington disease is a neurodegenerative disease caused by abnormal CAG trinucleotide repeats in exon one of the HTT gene, in which the number of CAG repeats affects disease presentation. Alleles with 40 or more CAG (cytosine, adenine, guanine) repeats are fully penetrant and age at disease onset is inversely correlated with number of repeats, while 36 to 39 CAG repeats are associated with reduced penetrance and fewer than 36 are not considered to cause Huntington disease. It is thought that inherited CAG repeats may undergo somatic expansion until a harmful threshold is reached before the degenerative process begins.

Pathology informatics selected abstracts

October 2024—The authors conducted a study to evaluate the Genius digital diagnostic system compared with manual light microscopy diagnosis using ThinPrep Pap test slides. Six cytologists and three cytopathologists participated in the study. They received 1.5 days of training on the Genius digital system from the manufacturer (Hologic, Marlborough, Mass.). They then analyzed 319 ThinPrep Pap test cases in the authors’ institutional cytology archive that represented a range of Bethesda System categories typically encountered in routine practice. The study participants assessed diagnostic accuracy by comparing digital and manual results to the original Pap test diagnosis, which was considered the reference diagnosis, or ground truth.

Clinical pathology selected abstracts

September 2024—Syphilis, an infectious disease caused by the spirochete bacterium Treponema pallidum, can be transmitted by blood transfusion. Therefore, donor blood has been routinely screened for syphilis since the 1950s. Although a case of transfusion-transmitted syphilis has not been documented in more than 50 years, routine serological testing is still performed because there is not sufficient evidence that it is no longer necessary. Syphilis testing can contribute to disease monitoring for overall public health by identifying infected blood donors so they can seek treatment to prevent further spread. The Transfusion Transmissible Infections Monitoring System (TTIMS) monitors infectious disease and demographic changes in donors who contribute approximately 60 percent of the U.S. blood supply, including at four major blood-collection organizations.

Anatomic pathology selected abstracts

September 2024—Research has shown assessment of tumor-associated stroma to be of reliable prognostic value. The authors conducted a study in which they evaluated the prognostic value of tumor-stroma ratio in a large multicenter cohort of nasopharyngeal carcinoma. They used the conventional H&E-stained slides of 115 cases of nasopharyngeal carcinoma to assess tumor-stroma ratio as described in recent guidelines. The amount of tumor-associated stroma was assessed as a percentage and then tumors were classified as stroma high (more than 50 percent) or stroma low (50 percent or less). Kaplan-Meier curves, a χ2 test, and Cox regression univariable and multivariable analyses were conducted.

Molecular pathology selected abstracts

September 2024—Oncology patients may benefit greatly from whole genome sequencing. Previous studies have suggested that it can provide relevant information pertaining to pediatric cancers, especially in selected cohorts of patients with high-risk disease. However, its clinical utility has not been thoroughly explored in routine clinical practice. The authors of this study examined the benefits of whole genome sequencing (WGS) in a consecutive cohort of pediatric patients from two institutions who required molecular workup for hematological neoplasms and solid tumors. Great Ormond Street Hospital, London, and Cambridge (England) University Hospitals offered WGS to patients with leukemia or solid tumors, respectively.

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