Webinars and Sponsored Roundtables — Register Now

Thursday, October 29, 2026, 1 PM-2 PM ET
Hear an expert discuss the evolving role of PD-L1 testing in HNSCC and ovarian cancer.

Webinar presenter Georgios Deftereos, MD, Professor of Pathology, Associate Director of the Clinical Cancer Genomics Laboratory, Director of Molecular Cytopathology, University of California, San Francisco

CAP TODAY does not endorse any of the products or services named within. The webinar is made possible by a special educational grant from Agilent.

Moderated by: Bob McGonnagle, Publisher, CAP TODAY

Tuesday, November 3, 2026, 1 PM-2 PM ET
Hear an expert discuss the challenges of detecting NRG1 fusions and how RNA-based testing can support more comprehensive fusion identification in clinical practice.

Webinar presenter Benjamin Weinberg, MD, Associate Professor of Medicine and Attending Physician
specializing in gastrointestinal medical oncology

CAP TODAY does not endorse any of the products or services named within. The webinar is made possible by a special educational grant from Diaceutics.

Moderated by: Bob McGonnagle, Publisher, CAP TODAY

Tuesday, November 10, 2026, 1 PM-2 PM ET
Join us for a session to help improve diagnostic accuracy in your practice when scoring HER2 IHC 0 with faint, incomplete membrane staining in ≤10% of tumor cells vs IHC 0 with no membrane staining detected in patients with mBC.

Webinar presenter Jeffrey Gregg, MD, University of Nevada

CAP TODAY does not endorse any of the products or services named within. This program is being sponsored by Daiichi Sankyo, Inc. and AstraZeneca. The speaker is being compensated for the presentation. The program is not CME accredited and may not be used for CME accreditation.

Moderated by: Bob McGonnagle, Publisher, CAP TODAY

Monday, November 16, 2026, 12:30 PM-2 PM ET
Hear experts discuss a multidisciplinary approach to oncopathology for HER2
assessments for solid tumors in the absence of a companion diagnostic.

Webinar presenters Funda Meric-Bernstam, MD, Chair, Department of Investigational Cancer Therapeutics Medical Director, Institute for Personalized Cancer Therapy, The University of Texas MD Anderson Cancer Center, Houston, Texas, and Emina E. Torlakovic, MD, PhD, College of Medicine, University of Saskatchewan, Canadian Biomarker Quality Assurance, Saskatoon, Saskatchewan, Canada, and Carol Cheung, MD, PhD, JD, FRCPC, Deputy Director, Canadian Biomarker Quality, Assurance—Programme canadien d’assurance de la qualité des biomarqueurs

CAP TODAY does not endorse any of the products or services named within. This program is being sponsored by Daiichi Sankyo, Inc. and AstraZeneca. The speaker is being compensated for the presentation. The program is not CME accredited and may not be used for CME accreditation.

Moderated by: Bob McGonnagle, Publisher, CAP TODAY

Subspecialties

Interactive Product Guides

Manage Subscription

To receive CAP TODAY magazine, please subscribe here.
For change of address, mail new information to: CAP TODAY Circulation, 325 Waukegan Road, Northfield, IL 60093-2750 or visit here.

All Issues

AI, privacy, and pathology practice: HIPAA loophole and the need for caution

September 2026—Technology and regulation have always co-evolved, and artificial intelligence should be no exception. “The tech industry would have Americans believe there should be no regulation of anything that has AI in its title until such time as the technology is fully matured and ready to be regulated,” says Brian R. Jackson, MD, MS, professor of pathology, director of clinical pathology, and CLIA director of laboratories, University of Maryland Medical Center. He calls it “complete gaslighting.”

DPA leaders on digitization, AI, and deployment

September 2026—What do leaders of the Digital Pathology Association have to say about where digital pathology stands now and what to expect from AI? Six DPA leaders met online July 24 with CAP TODAY publisher Bob McGonnagle to talk about the technology and the tools. Many patients still don’t understand pathology’s role, said Orly Ardon, PhD, MBA, of Memorial Sloan Kettering Cancer Center, “and AI can create additional concerns if it is not explained properly.”

AMP case report: Is undifferentiated sarcoma with EWSR1-POU5F1 fusion a molecularly defined entity?

September 2026—About 30 percent of soft tissue sarcomas are associated with chromosomal translocations leading to the formation of chimeric fusion genes that modify cellular function, leading to dysregulation of proliferation and resulting in clinically and genetically distinct neoplasms. EWSR1 is a commonly rearranged gene in sarcomas that can fuse as the 5’ partner with various genes. EWSR1-rearranged sarcomas include angiomatoid fibrous histiocytoma, clear cell sarcoma of soft parts, Ewing sarcoma, desmoplastic small round cell tumor (DSRCT), extraskeletal myxoid chondrosarcoma, myxoid liposarcoma, clear cell sarcoma-like tumors of the gastrointestinal tract, as well as round cell sarcoma with EWSR1-non-ETS fusions. Herein, we report an unusual case of EWSR1-POU5F1 fusion in an undifferentiated sarcoma. It has previously been described in myoepithelial tumors,3 but it has been described in undifferentiated sarcomas only a couple of times in the literature, to the best of our knowledge.

Move over, mouse—testing other input devices for WSIs

September 2026—As transitions to a digital pathology workflow grow in number, the question may become less about the extent to which digital slide assessment will be used in practice and more about how to work with those slides. While scanners, image management systems, and storage are most talked about, among other things, researchers at Western University in London, Ontario, turned their attention to the interface itself. They studied whether eye- and head-tracking technologies can serve as alternative input devices to hand-based input devices for digital pathology tasks.

From the President’s Desk

September 2026—From the CAP’s founding nearly 80 years ago, our organization has had a focus that sets us apart from all other pathology societies: our commitment to laboratory quality. Those of us in the U.S. are very familiar with the CAP accreditation process—which is widely considered the gold standard in laboratory accreditation—as the CAP has deemed status to accredit clinical laboratories under the U.S. Clinical Laboratory Improvement Amendments regulations.

Clinical pathology selected abstracts

September 2026—Three subtypes of inflammatory bowel disease present as chronic inflammation in children and adolescents: ulcerative colitis, Crohn’s disease, and IBD unclassified. The incidence of IBD continues to increase in pediatric populations, with a growing number of cases in preschool children. Familial patterns have been observed in 19 to 41 percent of patients, especially those younger than 11 years of age. The diagnosis of IBD is typically based on clinical presentation, endoscopic evaluation, and histological assessment of intestinal mucosa.

Anatomic pathology selected abstracts

September 2026—Autoimmune atrophic gastritis is chronic, immune-mediated inflammation restricted to the gastric body. Despite well-defined histologic features, its pathologic progression is still not fully understood. Therefore, the authors conducted a study to evaluate the pathologic progression of autoimmune atrophic gastritis. They reviewed cases with at least two follow-up biopsies.

Molecular pathology selected abstracts

September 2026—HIV remains a major global public health concern, with an estimated 40.8 million people living with the virus in 2024. The challenge is particularly striking in low- and middle-income countries, where access to diagnostic testing may be limited. The World Health Organization’s universal test-and-treat strategy recommends that patients diagnosed with HIV immediately begin antiretroviral therapy regardless of their CD4 cell count or clinical stage. This strategy has placed greater emphasis on routine viral load monitoring, leading to a marked decline in CD4 testing and the discontinuation of many point-of-care CD4 platforms.

Q&A column

September 2026
Q. What is the percent acceptability when conducting a comparison test of activated clotting times (ACT)? Read answer.
Q. Is there any circumstance in which a manual bone marrow differential would be more accurate than flow cytometric analysis? Read answer.

Newsbytes

September 2026—Twelve U.S. health systems have joined forces with the clinical artificial intelligence company Aidoc to form the Diagnostic AI Consortium, with the goal of harnessing AI to improve the safety, quality, and speed of patient diagnosis and developing and adhering to standards for evaluating and governing the capability.