Tuesday, October 20, 2026, 11 AM-12 PM ET
Hear experts review the biological and clinical significance of the HER2 expression continuum in breast tissue, providing a clearer understanding of how these variations might impact diagnosis, and discuss the emerging importance of documenting HER2-low and HER2-ultralow categories using a validated IHC assay.
Webinar presenters Keith Wharton, MD, PhD, Global Medical Affairs Leader–Pathology, Roche Diagnostics Solutions, and Hannah Y. Wen, MD, PhD, Director, Breast Pathology Fellowship, Associate Team Leader, Breast Pathology Team, Attending Pathologist, Memorial Sloan Kettering Cancer Center
CAP TODAY does not endorse any of the products or services named within. The webinar is made possible by a special educational grant from Roche.
Moderated by: Bob McGonnagle, Publisher, CAP TODAY
Thursday, October 29, 2026, 1 PM-2 PM ET
Hear an expert discuss the evolving role of PD-L1 testing in HNSCC and ovarian cancer.
Webinar presenter Georgios Deftereos, MD, Professor of Pathology, Associate Director of the Clinical Cancer Genomics Laboratory, Director of Molecular Cytopathology, University of California, San Francisco
CAP TODAY does not endorse any of the products or services named within. The webinar is made possible by a special educational grant from Agilent.
Moderated by: Bob McGonnagle, Publisher, CAP TODAY
Tuesday, November 3, 2026, 1 PM-2 PM ET
Hear an expert discuss the challenges of detecting NRG1 fusions and how RNA-based testing can support more comprehensive fusion identification in clinical practice.
Webinar presenter Benjamin Weinberg, MD, Associate Professor of Medicine and Attending Physician
specializing in gastrointestinal medical oncology
CAP TODAY does not endorse any of the products or services named within. The webinar is made possible by a special educational grant from Diaceutics.
Moderated by: Bob McGonnagle, Publisher, CAP TODAY
Monday, November 16, 2026, 12:30 PM-2 PM ET
Hear experts discuss a multidisciplinary approach to oncopathology for HER2
assessments for solid tumors in the absence of a companion diagnostic.
Webinar presenters Funda Meric-Bernstam, MD, Chair, Department of Investigational Cancer Therapeutics Medical Director, Institute for Personalized Cancer Therapy, The University of Texas MD Anderson Cancer Center, Houston, Texas, and Emina E. Torlakovic, MD, PhD, College of Medicine, University of Saskatchewan, Canadian Biomarker Quality Assurance, Saskatoon, Saskatchewan, Canada, and Carol Cheung, MD, PhD, JD, FRCPC, Deputy Director, Canadian Biomarker Quality, Assurance—Programme canadien d’assurance de la qualité des biomarqueurs
CAP TODAY does not endorse any of the products or services named within. This program is being sponsored by Daiichi Sankyo, Inc. and AstraZeneca. The speaker is being compensated for the presentation. The program is not CME accredited and may not be used for CME accreditation.
Moderated by: Bob McGonnagle, Publisher, CAP TODAY
August 2026—Kawasaki disease is an acute vasculitis of childhood and the most common cause of acquired heart disease in children worldwide. Up to 25 percent of untreated patients develop coronary artery aneurysms. The variable clinical presentation of Kawasaki disease (KD) complicates diagnosis, treatment, and understanding of the disease and highlights the need for molecular tools to stratify patients into biologically meaningful subgroups.
August 2026
Q. Are laboratories sticking to the established standard of spinning whole blood coagulation test tubes within four hours of specimen collection or are most changing to a 24-hour window (with some exceptions) per Clinical and Laboratory Standards Institute guidelines? Read answer.
Q. I am evaluating a large, well-circumscribed necrotic pelvic peritoneal implant in a case of serous borderline tumor (SBT) of the ovary. The implant shows nonviable necrotic tissue displaying only residual ghost papillary outlines with calcification. My initial interpretation is the peritoneal nodule is an invasive implant because it is large. I am assuming the necrosis represents infiltrative, destructive, and expansile neoplastic cells that form the large nodule (17 mm). I considered upgrading the SBT to low-grade serous carcinoma (LGSC) because of the presence of this implant. However, since the implant is necrotic, I cannot reliably evaluate for tumor cells. In addition, it is rare to have an invasive implant without an invasive component at the primary site. What is your opinion regarding this implant? Read answer.
August 2026—Pathologists and other cross-departmental staff at Beth Israel Lahey Health, in Boston, recently used an “all for one and one for all” approach to decision-making in evaluating image-management systems for purchase.
August 2026—Roche in June launched its Axelios 1, a next-generation single-molecule sequencing platform that it says will address bottlenecks in genomics and potentially in clinical research.
August 2026—The CAP introduced in its 2025 accreditation checklist edition GEN.20315 Risk Management, which says the laboratory’s quality management system uses a prospective risk management process. That process includes identification, control, and monitoring of risks throughout the laboratory.
July 2026—There’s an important election coming up, and it’s not the one you’ve been hearing about on the news. Voting will begin soon for new members of the CAP’s Board of Governors, and I urge you to take part.
July 2026—Sepsis is a major cause of pediatric morbidity and mortality worldwide. It is difficult to measure the number of pediatric sepsis cases since most estimates are based on administrative codes, and coding practices vary by institution. Medical record review offers greater accuracy in recording pediatric sepsis diagnoses, but it is labor intensive and subject to interrater variability.
July 2026—Hepatoid lung carcinomas, similar to hepatoid carcinomas of other sites, are defined as extrahepatic tumors exhibiting divergent hepatocellular differentiation. Uniquely, hepatoid carcinomas of the lung are reported to commonly express only HepPar1, which recognizes the mitochondrial enzyme carbamoyl-phosphate synthetase-1 (CPS1). HepPar1/CPS1 was recently found to accumulate in lung adenocarcinomas (LUAD) harboring STK11 mutations, presumably as a genotype-associated metabolic adaptation.
July 2026—Parkinson’s disease, which is characterized by loss of dopamine-producing neurons in the brain’s substantia nigra and the pathologic misfolding and accumulation of alpha-synuclein, can result in a range of motor and nonmotor symptoms that may vary by individual. The cardinal motor symptoms of Parkinson’s disease (PD) are bradykinesia (slowness of movement), resting tremor, rigidity, and postural instability. A prodromal phase of the disease can generate nonmotor symptoms, such as a reduced sense of smell years prior to the onset of cardinal motor symptoms.
July 2026—Apollo is a health care-scale multimodal foundation model designed to integrate longitudinal clinical data into unified virtual patient representations. It was developed by the authors using data from a major U.S. health care system and trained on approximately 25 billion clinical records from 7.2 million patients that spanned more than three decades. The data set incorporated 12 medical specialties and 28 clinical modalities, including pathology images, laboratory testing, clinical documentation, medications, and structured electronic health record data.
