Illumina launches TruSight Oncology 500
Nov. 1, 2018—Illumina launched its TruSight Oncology 500, a comprehensive next-generation sequencing assay. TSO 500 uses DNA and RNA to identify multiple variant types, including small nucleotide variants, indels, splice variants, fusions, and tumor mutational burden and microsatellite instability from the same formalin-fixed, paraffin-embedded tumor sample. The panel contains 1.94 Mb of genomic content to measure TMB and offers sophisticated variant calling and germline filtering algorithms for enhanced accuracy. “The importance of tumor mutational burden as a biomarker to predict immune