LC-free MALDI-TOF assay for protein C inhibitor, 9/13
SISCAPA Assay Technologies (SAT) announced publication of a study in Clinical Chemistry demonstrating that one of the company’s MALDI-TOF assays for protein C inhibitor can help identify patients at risk for recurrence of prostate cancer after radiotherapy. The assay measures a proteotypic peptide of protein C inhibitor enriched from tryptic digests of patient serum by anti-peptide antibodies (the SISCAPA, or Stable Isotope Standards and Capture by Anti-Peptide Antibodies, workflow), followed by quantitation using simple MALDI-TOF mass spectrometry. A significant post-treatment