Webinars and Commercial Conversations — Register Now

Tuesday, November 10, 2026, 1:00 PM-2 PM ET
Join us for a session to help improve diagnostic accuracy in your practice when scoring HER2 IHC 0 with faint, incomplete membrane staining in ≤10% of tumor cells vs IHC 0 with no membrane staining detected in patients with mBC.

Webinar presenter Samuel Caughron, MD, FCAP, Chief Strategy Officer, MAWD Pathology, Medical Director of Laboratory, AdventHealth Kansas City, Medical Director of Laboratory, Labcorp, President, Member & Director, Pathology Ventures, LLC

CAP TODAY does not endorse any of the products or services named within. This program is intended for US healthcare professionals. This program is being sponsored by AstraZeneca. The speaker is being compensated for the presentation. The program is not CME accredited and may not be used for CME accreditation.

Moderated by: Bob McGonnagle, Publisher, CAP TODAY

Monday, November 16, 2026, 12:30 PM-2 PM ET
Hear experts discuss a multidisciplinary approach to oncopathology for HER2
assessments for solid tumors in the absence of a companion diagnostic.

Webinar presenters Funda Meric-Bernstam, MD, Chair, Department of Investigational Cancer Therapeutics Medical Director, Institute for Personalized Cancer Therapy, The University of Texas MD Anderson Cancer Center, Houston, Texas, and Emina E. Torlakovic, MD, PhD, College of Medicine, University of Saskatchewan, Canadian Biomarker Quality Assurance, Saskatoon, Saskatchewan, Canada, and Carol Cheung, MD, PhD, JD, FRCPC, Deputy Director, Canadian Biomarker Quality, Assurance—Programme canadien d’assurance de la qualité des biomarqueurs

CAP TODAY does not endorse any of the products or services named within. This program is being sponsored by Daiichi Sankyo, Inc. and AstraZeneca. The speaker is being compensated for the presentation. The program is not CME accredited and may not be used for CME accreditation.

Moderated by: Bob McGonnagle, Publisher, CAP TODAY

Wednesday, November 18, 2026, 12:00 PM-1 PM ET
Join leading pathology experts, Savitri Krishnamurthy, MD, and Marilyn Bui, MD, PhD, for a webinar exploring potential challenges in HER2 IHC testing for breast cancer, emerging evidence supporting digital and computational pathology as assistive tools for pathologists in HER2 IHC assessment, and practical considerations for real-world implementation and adoption.

Webinar presenters Savitri Krishnamurthy, MD, Professor of Pathology, Department of Anatomical Pathology The University of Texas MD Anderson Cancer Center, Houston, Texas, and Marilyn Bui, MD, PhD, Surgical Pathologist and Cytopathologist Member and Professor, Departments of Pathology, Machine Learning, and Translational Pathology, Scientific Director, Analytic Microscopy Core Chair, Women in Oncology Executive Board Moffitt Cancer Center, Tampa, Florida

CAP TODAY does not endorse any of the products or services named within. This program is being sponsored by Daiichi Sankyo, Inc. and AstraZeneca. The speakers are being compensated for their presentations. The program is not CME accredited and may not be used for CME credit.

Moderated by: Bob McGonnagle, Publisher, CAP TODAY

Wednesday, December 9, 2026, 12 PM-1 PM ET
Hear an expert pathologist discuss the role of HER2 IHC testing and scoring in solid tumors including endometrial, ovarian, cervical, bladder, non-small cell lung, colorectal, and biliary cancers

Webinar presenter Michelle Shiller, DO, MSPT, Baylor Sammons Cancer Center; Fulgent Genetics; Texas Cancer Interception Institute

CAP TODAY does not endorse any of the products or services named within. This program is intended for US healthcare professionals. This program is being sponsored by AstraZeneca. The speaker is being compensated for the presentation. The program is not CME accredited and may not be used for CME accreditation.

Moderated by: Bob McGonnagle, Publisher, CAP TODAY

Subspecialties

Interactive Product Guides

Manage Subscription

To receive CAP TODAY magazine, please subscribe here.
For change of address, mail new information to: CAP TODAY Circulation, 325 Waukegan Road, Northfield, IL 60093-2750 or visit here.

Product Spotlight

Beckman Coulter

DxC 500i Clinical Analyzer

Company

Beckman Coulter

Name of instrument

DxC 500i Clinical Analyzer

Contact

Shannon Garegnani  

Email

sgaregnani@beckman.com

City, State

Brea, CA

Phone

800-526-3821  

Website

https://www.beckmancoulter.com

Type of instrument

combination chemistry/immunoassay

Operational type/Model type

continuous random access/floor standing

List price/First year sold in U.S.

—/2025

Targeted hospital bed size/Targeted test volume

—/annual: 50,000–350,000

Company manufactures instrument

yes (also sold by distribution partners)

Other models in this family of analyzers

DxC 500 AU, DxC 700 AU, AU5800, Access 2, DxI 600, DxI 9000 

No. of units in clinical use in U.S./Outside U.S. (countries)

—/— (worldwide)

Dimensions (H × W × D)/Instrument footprint

48.8 × 100 × 30.3 in./21 sq. ft.

Weight empty/Weight fully loaded

1,430 lbs./—

No. of different measured assays onboard simultaneously

—

No. of user-definable (open chemistry) channels

—

Test throughput per hour/Assay run time

800 chemistry with ISE, 100 immunoassay/—

No. of direct ion-selective electrode channels

—

Detection methods

photometry, potentiometry

Stat time until completion/specimen throughput for ion-selective electrode

—

Stat time until completion/specimen throughput for basic metabolic panel

—

Stat time until completion/specimen throughput for complete metabolic panel

—

Typical time delay from ordering stat test until aspiration of sample

—

Fully automated microplate immunoassay system

no

Methodologies supported

chemiluminescence

Separation methodologies

—

Stat time until completion of a ß-hCG test

—

Stat time until completion of a cTn test

—

• Typical time delay from test order to aspiration of sample

—

Approximate No. of tests per reagent set/Reagent type

50–6,744 per pack (varies by assay)/—

Reagents refrigerated onboard/Reagents ready to use

yes (4.5°–12°C)/variable; reagent specific

Reagent lot tracking/Reagent inventory

yes/yes

Reagent form/Reagents barcoded

liquid chemistry (open reagent system)/yes

Separate reagent pack for each specimen/for each test run

no/no

Walkaway capability/Walkaway duration

yes/168 specimens

Design of sample-handling system

rack

Uses washable cuvettes/Uses disposable cuvettes

yes (can store up to 88 cuvettes)/no

Min.–max. sample volume that can be aspirated at one time 

1–25 µL

Min. reaction volume/Min. specimen volume/Min. dead volume

90 µL/50 µL/80 µL

Dedicated pediatric sample cup

no

Primary tube sampling

yes

Accommodates most standard tube sizes/Accepts nonstandard tube sizes

yes/—

Pierces caps on primary tubes

no

Protects against probe collision

yes

Detects clots/liquid level/short sample

yes/yes/yes

Detection or quantitation for hemolysis, icterus, lipemia, clots

detection for hemolysis, icterus, lipemia, clots

Dilutes patient samples onboard/Susceptibility to carryover

yes (can be programmed to perform dilutions prior to analysis)/—

Automatic rerun capability

yes

Sample volume can be diluted to rerun out-of-linear-range high results

yes

Sample volume can be concentrated to rerun out-of-linear-range low results

yes

Autocalibration/Multipoint calibration supported

yes (calibrants are not stored onboard)/yes

Typical calibration frequency for ISE/therapeutic drugs/drugs of abuse/general chemistries/immunoassays

1 day/—/—/1–90 days/—

Automatic programmable start/Automatic programmable shutdown

—

Onboard real-time QC/Onboard software capability to review QC

yes/yes

Supports multiple QC lot numbers per analyte

yes

Waste management

direct to drain

Sample barcode-reading capability/Autodiscrimination

yes (Interleaved 2 of 5, Code 39, Code 128, NW7, EAN-13, ISBT 128, Standard 2 of 5)/—

Lab can control analyzer from remote computer

yes

Instrument can diagnose its own malfunctions

yes (instrument can order malfunctioning parts)

System malfunctions can be diagnosed via remote monitoring

yes

UPS backup power supply

yes

Data-management capability/LIS or EHR systems interfaced

onboard/Medicus, Evident, CGM LabDaq, Oracle Health, Clinisys

LIS interface provided/Bidirectional interface capability

yes (additional cost)/yes (host query)

Modem servicing provided/Service engineer on-site response time

—

Mean time between failures

—

Average scheduled maintenance time by lab personnel

daily: 9 min.; weekly: 26 min.; monthly: 45 min.

Maintenance records kept onboard for user/vendor

yes/no

Maintenance training demonstration module onboard

yes

Training included with purchase/Avg. time for basic user training

yes (2 training slots)/— (at customer site)

Advanced operator training/Extra charge for follow-up or advanced training

yes (at vendor site)/—

Warranty provided/Cost of annual service contract (24 h/7 d)

—

Distinguishing features (supplied by company)

independent and integrated operations, reagent load on the fly, rapid throughput; single point of sample loading, intuitive interface and guided workflows, easy to maintain parts; offers a menu of more than 170 assays for complete disease state management

More products
in this guide

DxC 500 AU Clinical Chemistry Analyzer
Pictus 500 (P500)
DS2 Elite Automated ELISA System
Stat Profile Prime Plus
VITROS XT 3400 Chemistry Systems
cobas pure integrated solutions 
B⋅R⋅A⋅H⋅M⋅S KRYPTOR compact PLUS