Linkedin Youtube
Launch Digital Edition

Webinars and Sponsored Roundtables — Register Now

Wednesday, September 30, 2026. 1 PM-1:30 PM ET
Roundtable presenters John Longshore, PhD, Head of Scientific Affairs, Global Oncology Diagnostics, AstraZeneca, and Flora Berisha, MS, Executive Director, Global Head of Diagnostic Partnering and Development, Johnson & Johnson Innovative Medicine, and Mark D. Ewalt, MD, Associate Medical Director for Laboratory Operations, Diagnostic Molecular Pathology, Molecular Diagnostics Service, Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, and Isabel Preeshagul, DO, MBS, Thoracic Medical Oncologist, Memorial Sloan Kettering Cancer Center

CAP TODAY does not endorse any of the products or services named within. The roundtable is made possible by a special educational grant from Pillar Biosciences.

Moderated by: Bob McGonnagle, Publisher, CAP TODAY

Register Now

Thursday, October 1, 2026 1 PM-2 PM ET
This presentation will explore the value of in-house CGP, offer insights into the benefits and drawbacks of incorporation, and provide information about important practical factors when considering in-house implementation of CGP.

Webinar presenter Allison M. Cushman-Vokoun, MD, PhD, FCAP, Medical Director, Molecular Diagnostics and Personalized Medicine Laboratory, Director, Division of Diagnostic Molecular Pathology and Human Genetics, Henry F. Krous Professor of Pathology, University of Nebraska Medical Center

CAP TODAY does not endorse any of the products or services named within. The webinar is made possible by a special educational grant from Illumina.

Moderated by: Bob McGonnagle, Publisher, CAP TODAY

Register Now

Tuesday, October 20, 2026 11 AM-12 PM ET
Hear experts review the biological and clinical significance of the HER2 expression continuum in breast tissue, providing a clearer understanding of how these variations might impact diagnosis, and discuss the emerging importance of documenting HER2-low and HER2-ultralow categories using a validated IHC assay.

Webinar presenters Keith Wharton, MD, PhD, Global Medical Affairs Leader–Pathology, Roche Diagnostics Solutions, and Hannah Y. Wen, MD, PhD, Director, Breast Pathology Fellowship, Associate Team Leader, Breast Pathology Team, Attending Pathologist, Memorial Sloan Kettering Cancer Center

CAP TODAY does not endorse any of the products or services named within. The webinar is made possible by a special educational grant from Roche.

Moderated by: Bob McGonnagle, Publisher, CAP TODAY

Register Now

Tuesday, November 3, 2026 1 PM-2 PM ET
Hear an expert discuss the challenges of detecting NRG1 fusions and how RNA-based testing can support more comprehensive fusion identification in clinical practice.

Webinar presenter Benjamin Weinberg, MD, Associate Professor of Medicine and Attending Physician
specializing in gastrointestinal medical oncology

CAP TODAY does not endorse any of the products or services named within. The webinar is made possible by a special educational grant from Diaceutics.

Moderated by: Bob McGonnagle, Publisher, CAP TODAY

Register Now

Subspecialties

Interactive Product Guides

2025 Issues

Clinical pathology selected abstracts

March 2025—Generative artificial intelligence is now readily available and has created a plethora of interest in health care, including in pathology and laboratory medicine. Unlike traditional AI, generative AI (Gen­AI) doesn’t rely solely on historical data to make predictions but instead uses patterns within historical data to create entirely new data. Excitement over Gen­AI must be weighed against the reality of maintaining human control over the technology and interpreting the data. The use of Gen­AI in health care may include not only streamlining administrative tasks but also performing safety critical clinical functions, such as image-based diagnosis. The risk-based approach and quality management of Gen­AI must be managed individually for each situation.

Anatomic pathology selected abstracts

March 2025—Invasive lobular carcinoma is characterized by loss of E-cadherin expression and CDH1 gene inactivation. The reliability and reproducibility of diagnosis for this tumor type is suboptimal and could be improved by better understanding the histomolecular and clinical heterogeneity of such tumors. The authors analyzed the relationship between the presence, type, or position of CDH1 mutations, E-cadherin expression, and clinicopathological features, including outcome, in a retrospective series of 251 primary invasive lobular carcinomas (ILC) with a median follow-up of 9.5 years. The mutational status of CDH1 (the gene encoding E-cadherin) was determined by RNA sequencing of frozen tumor samples. E-cadherin immunohistochemistry was performed with antibodies directed against the intracellular (clone 4A2C7) and extracellular (clone NCH38) domains.

Molecular pathology selected abstracts

March 2025—Genomic imprinting is an epigenetic process that results in expression of only one copy of a gene—either from a person’s mother or father—while the other parent’s copy of the same gene is silenced. A cluster of genes affected by imprinting on the proximal part of the long arm of chromosome 15 (15q11-q13) are associated with syndromic conditions. Deficient expression of the maternally inherited copy of UBE3A in this region results in Angelman syndrome, which is characterized by severe developmental delay, gait ataxia, and an apparent happy demeanor with profuse smiling, frequent laughing, and excitability. In contrast, deficient expression of paternally inherited genes in this region causes Prader-Willi syndrome. Clinical features of this condition can vary but often include developmental delay, short stature, hyperphagia, and obesity.

Newsbytes

March 2025—Delays while a courier is sent to the blood bank. Errors in judgment. Omission of steps in tracking who received a unit of blood. Wastage of blood product because clinicians were cautious and overordered or ordered too soon. Staffing issues. All of these potential blood bank-related problems can be mitigated with smart blood-storage devices, also called smart refrigerators or blood vending machines.

Q&A column

March 2025
Q. When should plasma mixing tests be performed in the coagulation laboratory, and how are they best interpreted? Read answer.

Q. How important is it for a laboratory to perform whole mount specimen collection and examination? Read answer.

Put It on the Board

March 2025—The Roche Tina-quant Lipoprotein (a) Gen.2 Molarity assay received 510(k) clearance from the Food and Drug Administration. It is the first 510(k)-cleared test of its kind available in the U.S. to measure lipoprotein(a) in nanomoles per liter. It will be broadly available on Cobas c analyzers. Lp(a) can vary in size and has no single, defined molecular weight. For this reason, Roche says, there is a consensus in the scientific community that Lp(a) levels should be measured in terms of the number of particles per liter of blood (nmol/L), rather than mass units (mg/dL), and that any conversion between mass and molar units is generally imprecise and unreliable. By using molar units, laboratory professionals and clinicians know the Lp(a) measurements reflect the number of particles rather than a difference in particle size.

Room to grow: tumor-germline sequencing

February 2025—Genetic profiling has long had proven winners in oncology: somatic testing of tumors, and germline testing for surveillance and to identify potentially affected relatives.

The shift from cotesting to primary HPV screening

February 2025—Eric Huang, MD, PhD, is the first to admit that when it came time to switch to primary HPV testing, his laboratory at the University of Washington faced fewer obstacles than most. Dr. Huang joined the university in 2018 as director of the cytopathology laboratory.

In chemistry and more, what to know about new checklist edition

February 2025—In the 2024 accreditation program checklist edition, released Dec. 26, are new and revised requirements for chemistry, diagnostic immunology, and flow cytometry laboratories. Two of the flow cytometry requirements are now also in the anatomic pathology checklist.

MARKETPLACE

TRENDING