Linkedin Youtube
Launch Digital Edition

Webinars and Sponsored Roundtables — Register Now

Thursday, October 29, 2026, 1 PM-2 PM ET
Hear an expert discuss the evolving role of PD-L1 testing in HNSCC and ovarian cancer.

Webinar presenter Georgios Deftereos, MD, Professor of Pathology, Associate Director of the Clinical Cancer Genomics Laboratory, Director of Molecular Cytopathology, University of California, San Francisco

CAP TODAY does not endorse any of the products or services named within. The webinar is made possible by a special educational grant from Agilent.

Moderated by: Bob McGonnagle, Publisher, CAP TODAY

Register Now

Tuesday, November 3, 2026, 1 PM-2 PM ET
Hear an expert discuss the challenges of detecting NRG1 fusions and how RNA-based testing can support more comprehensive fusion identification in clinical practice.

Webinar presenter Benjamin Weinberg, MD, Associate Professor of Medicine and Attending Physician
specializing in gastrointestinal medical oncology

CAP TODAY does not endorse any of the products or services named within. The webinar is made possible by a special educational grant from Diaceutics.

Moderated by: Bob McGonnagle, Publisher, CAP TODAY

Register Now

Tuesday, November 10, 2026, 1 PM-2 PM ET
Join us for a session to help improve diagnostic accuracy in your practice when scoring HER2 IHC 0 with faint, incomplete membrane staining in ≤10% of tumor cells vs IHC 0 with no membrane staining detected in patients with mBC.

Webinar presenter Jeffrey Gregg, MD, University of Nevada

CAP TODAY does not endorse any of the products or services named within. This program is being sponsored by Daiichi Sankyo, Inc. and AstraZeneca. The speaker is being compensated for the presentation. The program is not CME accredited and may not be used for CME accreditation.

Moderated by: Bob McGonnagle, Publisher, CAP TODAY

Register Now

Monday, November 16, 2026, 12:30 PM-2 PM ET
Hear experts discuss a multidisciplinary approach to oncopathology for HER2
assessments for solid tumors in the absence of a companion diagnostic.

Webinar presenters Funda Meric-Bernstam, MD, Chair, Department of Investigational Cancer Therapeutics Medical Director, Institute for Personalized Cancer Therapy, The University of Texas MD Anderson Cancer Center, Houston, Texas, and Emina E. Torlakovic, MD, PhD, College of Medicine, University of Saskatchewan, Canadian Biomarker Quality Assurance, Saskatoon, Saskatchewan, Canada, and Carol Cheung, MD, PhD, JD, FRCPC, Deputy Director, Canadian Biomarker Quality, Assurance—Programme canadien d’assurance de la qualité des biomarqueurs

CAP TODAY does not endorse any of the products or services named within. This program is being sponsored by Daiichi Sankyo, Inc. and AstraZeneca. The speaker is being compensated for the presentation. The program is not CME accredited and may not be used for CME accreditation.

Moderated by: Bob McGonnagle, Publisher, CAP TODAY

Register Now

Subspecialties

Interactive Product Guides

Manage Subscription

To receive CAP TODAY magazine, please subscribe here.
For change of address, mail new information to: CAP TODAY Circulation, 325 Waukegan Road, Northfield, IL 60093-2750 or visit here.

2025 Issues

Clinical pathology selected abstracts

October 2025—Whole genome sequencing is being evaluated in newborn screening to increase the diagnosis and treatment of rare clinical conditions. Such screening raises ethical questions about which results to report and the impact of those results on parents and their children. It is important to focus on societal norms when designing whole genome sequencing–newborn screening (WGS-NBS) to make sure people accept the testing and minimize patient harm. Although parents value the fact that WGS-NBS can lead to early diagnosis and treatment of various conditions, they recognize that results may cause psychological distress, eliminate children’s autonomy, raise data-storage and privacy concerns, and lead to uncertainty regarding adult-onset medical conditions. The public, in general, supports WGS-NBS for clinically actionable childhood-onset conditions, with the caveats that health professionals are trained to interpret such results and genetic counseling is available.

Anatomic pathology selected abstracts

October 2025—Crystal-storing histiocytosis is a rare disorder in which crystals accumulate in the cytoplasm of histiocytes. It is usually associated with a lymphoplasmacytic neoplasm. Cutaneous crystal-storing histiocytosis (CSH) is extraordinarily rare and limited to case reports in the literature. The authors reported on two cases of CSH with cutaneous involvement. Case one was a 65-year-old male with a four-month history of a pruritic eruption that started as a solitary pink to skin-colored indurated plaque on the anterior neck before progressing to involve the whole neck, chest wall, and face.

Molecular pathology selected abstracts

October 2025—GATA2 deficiency is a rare inherited condition that disrupts the normal development of blood and immune cells. People born with this genetic disorder may experience low blood counts, frequent infections, or such problems as lymphedema and hearing loss. The most serious long-term risk is development of myelodysplastic syndrome (MDS), a bone marrow disorder that can progress to leukemia. The authors conducted a large study in which they followed 218 people with confirmed GATA2 mutations to understand when and how MDS develops. In this cohort, symptoms of GATA2 deficiency were present in 205 of the participants, of whom 187 (91.2 percent) had MDS.

Pathology informatics selected abstracts

October 2025—Large language models are becoming commonplace for personal and business use. The health care community is leveraging large language models (LLMs) for various purposes. Researchers at the University Medical Center Hamburg-Eppendorf, Hamburg, Germany, have successfully used open-source LLMs to extract critical medical data from pathology reports. They conducted a study that demonstrated how LLMs can transform unstructured clinical text into structured pathology data. While pathology reports are rich in information about tumor type, size, and stage, their narrative format makes automated data extraction difficult.

Q&A column

October 2025
Q. Is telepathology used much in the United States for histology interpretation and diagnosis? For example, is it used to interpret digitally transmitted histology slides when working from home? Read answer.

Q. When a patient has a hematocrit level of ≥ 55 percent and a normal PT and APTT, do you still correct sodium citrate and ask for a redraw? Is it crucial to ask for a redraw when the emergency department orders a stat PT and APTT? Read answer.

Newsbytes

October 2025—For pathology residents, there are easier tasks than writing a perfect preliminary case report on the first attempt. Nailing Jell-O to a tree, for example, or stapling sunlight to a cloud. “When the attendings make no changes or just sign out the case as we wrote it, there’s a sense of accomplishment,” says Jingjing Cao, MD, pathology resident in the Departments of Pathology and Laboratory Medicine, University of California San Francisco.

Put It on the Board

October 2025—Send-out and other high-cost tests are the typical targets of lab stewardship, but a clinical decision support session at the ADLM meeting in July had a different focus: daily labs. It’s generally believed there is little to no opportunity for savings on daily labs because the reagent cost per test is low, as is the incremental labor savings for tests performed on automated instruments. Instead, said Grace Mahowald, MD, PhD, informatician and director of the core laboratory at Massachusetts General Hospital, “think about what goes into the cost of each of our daily lab tests,” from the nurse, patient care assistant, and phlebotomist to the specimen transporter and the lab receiving staff and technical staff who review results and call providers when specimens have to be refused at receipt. “And it’s questionable if people are even looking at the result,” she said.

Where court’s LDT decision leaves labs

September 2025—The Food and Drug Administration’s efforts to regulate laboratory-developed tests as medical devices came to a decisive halt this spring with a ruling from the U.S. District Court …

How a core lab took back its outpatient business

September 2025—Angela Vetch, MPH, DLM(ASCP), is tired of reading about large commercial labs buying hospital laboratories’ outreach business. “There is an alternative to that story,” said Vetch, director of laboratory services at Kootenai Health, a three-hospital system in Coeur d’Alene, Idaho.

At AMP, latest on self-collection, avian influenza, and more

September 2025—Avian influenza, self-collection, and diagnostic stewardship in the microbiology laboratory are three topics of many that can be explored at the Association for Molecular Pathology meeting in Boston this November. Andrew Pekosz, PhD, heads a research laboratory at Johns Hopkins University that studies the replication and disease potential of emerging respiratory viruses.

MARKETPLACE

TRENDING