Molecular Pathology Abstracts, 6/17
June 2017—Whole genome single-cell copy number profiling on FFPE tissue samples
Single-cell genomic methods take the concept of analyzing intratumor genetic heterogeneity to its logical conclusion. Traditionally, however, single-cell methods can only be used to analyze fresh or rapidly frozen tissue because formalin fixation and paraffin embedding degrades tumor DNA and cross-links proteins.