Building a better blood order, front to back
October 2025—For all the effort, redos, build-outs, planning, talking, and time that went into revamping blood product orders at Children’s Healthcare of Atlanta, the essence can be …
Webinars and Sponsored Roundtables — Register Now
Tuesday, April 28, 2026, 12:00 PM–1:00 PM ET
Discover how next-day comprehensive genomic profiling (CGP) is possible with the Oncomine Comprehensive Assay Plus on the Genexus System—delivering both speed and accuracy.
Webinar presenters Jane Bayani, MHSc, PhD, Assistant Professor and Co-Director, Diagnostic Development, Ontario Institute for Cancer Research, Canada, and Nicola Normanno, MD, Scientific Director, IRCCS Romagnolo Institute for the Study of Tumors, Italy, and Morten Grauslund, PhD, Molecular Biologist, Department of Pathology, Rigshospitalet/Copenhagen University Hospital, Copenhagen, Denmark.
Moderated by: Bob McGonnagle, Publisher, CAP TODAY
CAP TODAY does not endorse any of the products or services named within. The webinar is made possible by a special educational grant from Thermo Fisher Scientific. For Research Use Only. Not for use in diagnostic applications.
Thursday, April 30, 2026, 11:00 AM–12:00 PM ET
Hear an expert discuss how Memorial Sloan Kettering Cancer Center (MSKCC) is utilizing
the oncoReveal® Nexus 21-gene panel to redefine turnaround time and actionable insights
in cancer care. Dr. Ewalt shares a perceptive look at the clinical need for rapid, front-line NGS sequencing, and how a unique, purpose built targeted NGS panel (Pillar Biosciences’ oncoReveal Nexus 21 gene Panel) was developed, validated and implemented clinically by Memorial Sloan Kettering Cancer Center (MSK-REACT) to complement their current comprehensive genomic profiling (CGP) approach.
Webinar presenter Mark Ewalt, MD, Associate Medical Director for Laboratory Operations for Diagnostic Molecular Pathology in the Molecular Diagnostics Service, Department of Pathology and Laboratory Medicine, MSKCC.
Moderated by: Bob McGonnagle, Publisher, CAP TODAY
CAP TODAY does not endorse any of the products or services named within. The webinar is made possible by a special educational grant from Pillar Biosciences.
Thursday, May 28, 2026, 1:00–2:00 PM ET
This session is designed to improve understanding and application of recent updates to synoptic pathology reporting protocols such as the latest Reporting Template for Reporting Results of Biomarker Testing of Specimens from Patients with Carcinoma of the Breast. These changes reflect evolving clinical guidelines that directly influence diagnostic accuracy and treatment selection in breast cancer care.
Webinar presenters Thaer Khoury, MD, FCAP, Chair, Pathology and Laboratory Medicine, Roswell Park Comprehensive Cancer Cente, and Colin Murphy, CEO of mTuitive.
Moderated by: Bob McGonnagle, Publisher, CAP TODAY
Subspecialties
Interactive Product Guides
October 2025
Sample flags, low anion gap—solving lab puzzles
October 2025—Speakers in a session at the ADLM meeting in July walked attendees through their real-life cases and quandaries that called for troubleshooting skill and left their laboratories with lessons learned from each. Offering up what they called lab adventures were Joe M. El-Khoury, PhD, DABCC, professor of laboratory medicine at Yale School of Medicine; Christopher Farnsworth, PhD, DABCC, associate professor of pathology and immunology at Washington University School of Medicine in St. Louis; and Reid Rosehill, MS, MLS(ASCP), laboratory manager at the University of California San Francisco.
The push for equity in CF carrier and newborn screening
October 2025—Bringing equity to cystic fibrosis carrier and newborn screening was the aim of expert groups that have released their recommendations for both. Carrier screening for 23 CFTR variants, which had been the recommended practice since 2004, was working well, “but only if a person was of white European or Ashkenazi Jewish ancestry,” said Karen Raraigh, MGC, CGC, assistant professor of genetic medicine at Johns Hopkins University. “It wasn’t working all that well because it was not an equitable test.” For people of Asian American and African American ancestry, she said, the detection rate was lower.
Unconventional tests raise stewardship questions
October 2025—Complementary and integrative medicine (CIM) has become gradually more popular and is accepted by a small but significant group of patients in tandem with traditional medicine. CIM providers often advocate a mix of conventional tests with special test panels that may include tens to hundreds of tests that conventional providers wouldn’t order. For those who lead laboratory stewardship efforts, it can be a challenge.
How far? How much? What labs say about digital path
October 2025—Glass or digital, onsite or remote—and what the rules are for the latter. That’s what Compass Group lab leaders talked about with CAP TODAY publisher Bob McGonnagle when they met online on Sept. 2. Here’s a glimpse into their digital pathology journeys. The Compass Group is an organization of not-for-profit IDN system laboratory leaders who collaborate to identify and share best practices and strategies.
New forensic pathology book offers best of all others
October 2025—CAP Publications has released its newest book, Forensic Pathology: Principles and Pitfalls. It comes more than 20 years after the second edition of the CAP Handbook of Forensic Pathology was published. The book’s more than 900 pages comprise 36 chapters written by 57 contributors. CAP TODAY asked the following questions of the editors—Joseph Prahlow, MD, and Erin Brooks, MD—who led the publication of the comprehensive update.
AMP case report: Unique patterns of BTK resistance: two independently arising resistance clones in response to covalent BTK inhibitor therapy in CLL/SLL
October 2025—Chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) is a mature B-cell neoplasm composed of small atypical lymphoid cells that often coexpress CD5 and CD23 and are characterized by scant cytoplasm, clumped nuclear chromatin, and indistinct nucleoli. CLL/SLL can involve the peripheral blood, bone marrow, and various lymphoid tissues such as the lymph nodes, tonsils, and spleen, and it may occasionally present in extranodal locations as well.1 Within involved lymph nodes, pale-staining proliferation centers consisting of prolymphocytes or paraimmunoblasts are a characteristic finding in CLL/SLL.
From the President’s Desk
October 2025—For my inaugural column in CAP TODAY, I’d like to begin by saying thank you. Thank you, CAP members, for the honor of allowing me to serve as your president. Thanks to my mentors, peers, and colleagues for helping me along this path. And my deepest gratitude to my wife, Jenny, and my daughter, Jasmine, for the extraordinary journey that began in China and led to my own American dream in the U.S. and to Louisiana, where I practice.
Clinical pathology selected abstracts
October 2025—Whole genome sequencing is being evaluated in newborn screening to increase the diagnosis and treatment of rare clinical conditions. Such screening raises ethical questions about which results to report and the impact of those results on parents and their children. It is important to focus on societal norms when designing whole genome sequencing–newborn screening (WGS-NBS) to make sure people accept the testing and minimize patient harm. Although parents value the fact that WGS-NBS can lead to early diagnosis and treatment of various conditions, they recognize that results may cause psychological distress, eliminate children’s autonomy, raise data-storage and privacy concerns, and lead to uncertainty regarding adult-onset medical conditions. The public, in general, supports WGS-NBS for clinically actionable childhood-onset conditions, with the caveats that health professionals are trained to interpret such results and genetic counseling is available.
Anatomic pathology selected abstracts
October 2025—Crystal-storing histiocytosis is a rare disorder in which crystals accumulate in the cytoplasm of histiocytes. It is usually associated with a lymphoplasmacytic neoplasm. Cutaneous crystal-storing histiocytosis (CSH) is extraordinarily rare and limited to case reports in the literature. The authors reported on two cases of CSH with cutaneous involvement. Case one was a 65-year-old male with a four-month history of a pruritic eruption that started as a solitary pink to skin-colored indurated plaque on the anterior neck before progressing to involve the whole neck, chest wall, and face.