June 2026—In the cat-and-mouse maneuverings that often propel new cancer treatments, menin inhibitors are proving to be successful epigenetic therapies for acute leukemia. Last November brought FDA approval of revumenib for treatment of adults and children (one year and older) with relapsed or refractory acute myeloid leukemia with NPM1 gene mutations.
and Dr. Ghayas Issa
June 2026—Despite elevated Lp(a) concentration having a high population prevalence of about 20 percent, the testing rate has been low, and that is about to change.
June 2026—The immunostaining landscape for lung neuroendocrine tumors continues to evolve, and Humberto Trejo Bittar, MD, in a CAP25 lung cancer session last fall, captured where it stands.
June 2026—CAP TODAY publisher Bob McGonnagle spoke on March 12 with Jessica Van Allen, PhD, technical support lead for ZeptoMetrix, and Jesse M. Young, PhD, medical director for TriCore Research Institute’s research and clinical trials department and director of point-of-care testing. Dr. Young is also clinical assistant professor at the University of New Mexico.
Bob McGonnagle: Dr. Young, tell us about TriCore and the laboratories you oversee.
Dr. Young (TriCore): TriCore Reference Laboratory is a full-service diagnostic laboratory. The core laboratory offers about 2,900 test codes and has a modality similar to that of Labcorp and Quest, but we’re focused on New Mexican populations. We serve most of the hospitals in the area and have statewide collection sites whereby we’re trying to expand health care and provide coverage for our communities so everyone in the state has access to health care near their home instead of having to drive six hours to the nearest collection site, drive home, and then be called back for a critical value. Continue reading …
This roundtable discussion is sponsored by ZeptoMetrix.
CAP TODAY RECOMMENDS
February 2026—Prepared with expert insight from Anil Parwani, MD, PhD; Scott Hammond; and Melinda Schumacher, MD, Grundium’s white paper describes, from a pathologist’s perspective, how compact WSI systems can shorten consult turnaround times and reduce variability, improve access to subspecialty review without adding travel or courier burden, enhance community pathologists’ professional satisfaction and confidence, support scalable, secure, and validated workflows and lay the foundation for AI and advanced analytics as digital adoption grows. Download the white paper here.
June 2026—Serving on a CAP council or committee is a prestigious and valuable thing to do—but the path to getting there can seem almost impossible to navigate. In recent years, the CAP has changed the process to make it as transparent as possible and to give more people an opportunity to get involved. I’d like to shine a light on committee and council participation to help demystify one of the most important ways you can become more engaged with the CAP.
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FEATURED GUIDE: chemistry/immunoassay analyzers for low-volume labs
June 2026—Instrumentation for all laboratory testing sites—large and small—was the roundtable topic on April 21 when representatives of Roche, Beckman Coulter, and Siemens Healthineers met online with Moira Larsen, MD, MBA, of MedStar, and Joe Baker of Baylor Scott & White. CAP TODAY publisher Bob McGonnagle led, with questions about, among other things, AI, testing consolidation, what laboratories expect of vendors, and what laboratories are willing to contribute to the partnership. “We’re happy to help figure out what the bugs are,” Baker says of new instrumentation.
PRODUCT GUIDE ROUNDTABLES
May 2026—Preserving tissue for molecular and other biomarker studies is top of mind for many, and in a CAP25 lung cancer session last fall, an approach to doing so was presented.
May 2026—Has your blood collection container been validated for the assays you have employed it for? At what point does a verification of a blood collection tube become a validation, and how is a laboratory supposed to know when this threshold has been crossed and what actions to take?
May 2026—Cystatin C has notable advantages over serum creatinine as a biomarker of kidney filtration: fewer nonglomerular filtration rate determinants, more accurate dosing of medications with narrow therapeutic windows for individuals with obesity or low muscle mass, and greater accuracy in determining eligibility for a kidney transplant or for a simultaneous liver-kidney or heart-kidney transplant.
MARKETPLACE
June 2026—Streck launched CD-Chex Daily, a ready-to-use quality control for flow cytometry laboratories. It provides coverage across 51 assayed, research-use-only markers in a single vial, with markers spanning surface, intracellular, and leukocyte scatter populations, including CD200, TRBC1, cMPO, CD27, CD36, CD81, cCD79a, CD79b, cKappa, cLambda, and others.