Webinars and Sponsored Roundtables — Register Now

Wednesday, September 23, 2026. 12 PM-1 PM ET
Roundtable presenters Dr. David Sacks MB, ChB, FRCPath, Chairman, Steering Committee National Glycohemoglobin Standardization Program (NGSP), and Priya Sivaraman, PhD, Senior Technical Product Manager, Tosoh Bioscience

CAP TODAY does not endorse any of the products or services named within. The roundtable is made possible by a special educational grant from Tosoh Bioscience Inc.

Moderated by: Bob McGonnagle, Publisher, CAP TODAY

Thursday, September 24, 2026 11 AM-12 PM CT
This session explores the evolving role of RAS in precision oncology, from the biology of RAS mutations to the expanding landscape of targeted therapies. Through expert presentations, real-world case discussions, and interactive audience polling, participants will examine best practices for RAS biomarker testing across solid tumors, including lung, colorectal, and pancreatic cancers. The session will highlight practical considerations for tissue and liquid biopsy, strategies to address testing gaps, and the importance of multidisciplinary collaboration to ensure timely identification of patients who may benefit from RAS-targeted therapies.

Webinar presenters David Braxton, MD, Chief of Molecular Pathology Services, Hoag Family Cancer Institute & Hoag Memorial Hospital Presbyterian, and Carlos Becerra, MD, Research Director for Medical Oncology, Margaret Given Larkin Endowed Chair for Developmental Cancer Therapeutics, Hoag Memorial Hospital Presbyterian

CAP TODAY does not endorse any of the products or services named within. The webinar is made possible by a special educational grant from OncoLens and Diaceutics.

Moderated by: Bob McGonnagle, Publisher, CAP TODAY

Wednesday, September 30, 2026. 1 PM-1:30 PM ET
Roundtable presenters John Longshore, PhD, Head of Scientific Affairs, Global Oncology Diagnostics, AstraZeneca, and Flora Berisha, MS, Executive Director, Global Head of Diagnostic Partnering and Development, Johnson & Johnson Innovative Medicine, and Mark D. Ewalt, MD, Associate Medical Director for Laboratory Operations, Diagnostic Molecular Pathology, Molecular Diagnostics Service, Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, and Isabel Preeshagul, DO, MBS, Thoracic Medical Oncologist, Memorial Sloan Kettering Cancer Center

CAP TODAY does not endorse any of the products or services named within. The roundtable is made possible by a special educational grant from Pillar Biosciences.

Moderated by: Bob McGonnagle, Publisher, CAP TODAY

Thursday, October 1, 2026 1 PM-2 PM ET
This presentation will explore the value of in-house CGP, offer insights into the benefits and drawbacks of incorporation, and provide information about important practical factors when considering in-house implementation of CGP.

Webinar presenter Allison M. Cushman-Vokoun, MD, PhD, FCAP, Medical Director, Molecular Diagnostics and Personalized Medicine Laboratory, Director, Division of Diagnostic Molecular Pathology and Human Genetics, Henry F. Krous Professor of Pathology, University of Nebraska Medical Center

CAP TODAY does not endorse any of the products or services named within. The webinar is made possible by a special educational grant from Illumina.

Moderated by: Bob McGonnagle, Publisher, CAP TODAY

Tuesday, October 20, 2026 11 AM-12 PM ET
Hear experts review the biological and clinical significance of the HER2 expression continuum in breast tissue, providing a clearer understanding of how these variations might impact diagnosis, and discuss the emerging importance of documenting HER2-low and HER2-ultralow categories using a validated IHC assay.

Webinar presenters Keith Wharton, MD, PhD, Global Medical Affairs Leader–Pathology, Roche Diagnostics Solutions, and Hannah Y. Wen, MD, PhD, Director, Breast Pathology Fellowship, Associate Team Leader, Breast Pathology Team, Attending Pathologist, Memorial Sloan Kettering Cancer Center

CAP TODAY does not endorse any of the products or services named within. The webinar is made possible by a special educational grant from Roche.

Moderated by: Bob McGonnagle, Publisher, CAP TODAY

Tuesday, November 3, 2026 1 PM-2 PM ET
Hear an expert discuss the challenges of detecting NRG1 fusions and how RNA-based testing can support more comprehensive fusion identification in clinical practice.

Webinar presenter Benjamin Weinberg, MD, Associate Professor of Medicine and Attending Physician
specializing in gastrointestinal medical oncology

CAP TODAY does not endorse any of the products or services named within. The webinar is made possible by a special educational grant from Diaceutics.

Moderated by: Bob McGonnagle, Publisher, CAP TODAY

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Q&A column

August 2025
Q. We manage multispecialty laboratories in multiple hospital locations. Most of the laboratories function on the traditional model of compartmentalized specialty-based testing units that offer routine and specialized services with their own dedicated space, equipment, and personnel. There is a future plan to establish an offsite centralized referral lab, but to improve operational efficiency and cost savings sooner, management is considering consolidating testing services at each location. What factors should be considered while planning the consolidation, keeping in mind the plan to establish a centralized reference lab? Should the testing services that will eventually be performed in the reference lab be excluded from the current consolidation plan? And how should we manage operations during the transition phase, i.e. once consolidation is completed but prior to the reference lab implementation? Read answer.

Q. We have been discussing supervisory review of test results that are manually entered into our laboratory information system (i.e. a test result not sent via interface from an analyzer or autoverified). Examples are a urine hCG performed on a kit cassette or a manual differential performed on a CBC, entered directly into the LIS by the performing technologist. Do manual test results require supervisory review, or is it only higher-complexity tests (like the differential) performed by a medical laboratory technologist that require such review? If review is required, who can review and what is the recommended time frame? Read answer.

Put It on the Board

August 2025—In a position statement released in July, the CAP urged policymakers to consider scientific and logistical evidence and to protect the integrity and safety of the national blood supply. The statement was issued in response to legislation proposed in several states that would require blood product labeling based on donor vaccination status or mandate hospitals and blood collectors to honor requests for directed and autologous donations. Misinformation surrounding COVID-19 and mRNA vaccines has led to a growing number of patient requests for blood transfusions exclusively from unvaccinated donors.

Shorts on Standards: ISO/TS 23824 can help take anatomic pathology quality to another level

July 2025—The International Organization for Standardization (ISO) published a new technical specification, ISO/TS 23824 (Medical Laboratories—Guidance on Application of ISO 15189 in Anatomic Pathology), on the application of ISO 15189 to anatomic pathology. Although structured around the clauses of ISO 15189, the document offers useful guidance, ideas, and concepts applicable to any AP laboratory, including every AP laboratory in the United States that has to comply with CLIA ’88 or CAP Laboratory Accreditation Program requirements.

From the President’s Desk

July 2025—Whether we’re in academic or private practice, hospital labs or independent labs, as pathologists we share a broad set of common responsibilities and challenges. But a select group of us has an additional set of considerations for how to practice because of who and where they serve. In this month’s column, I’d like to shine a light on military pathologists and pathologists who serve our veterans in the Veterans Affairs health system—all of whom are supporting the defense of our country.

Clinical pathology selected abstracts

July 2025—A large number of cancers remain undetected until later stages, including lung, colorectal, cervical, ovarian, pancreatic, and prostate cancers. The U.S. Preventive Services Task Force recommends screening based on age and other risk factors. It is estimated that more than 4 million cancers have been avoided due to early screening methods. Efforts are being made to develop cancer-screening tests that are easier to perform and less invasive and that detect multiple types of cancer, with the intent of reducing cancer-related morbidity and mortality. Multicancer early detection (MCED) assays depend on circulating cell-free DNA to detect a shared single cancer signal.

Anatomic pathology selected abstracts

July 2025—Intraductal oncocytic papillary neoplasm of the pancreas is a recently recognized pancreatic tumor. The authors conducted a study to generate a comprehensive and quantitative summary of various aspects of intraductal oncocytic papillary neoplasms (IOPN). They searched the PubMed, Scopus, and Embase databases for studies reporting on pancreatic IOPN. Clinicopathologic, immunohistochemical, and molecular data were extracted from the studies and summarized. A comparative analysis of the molecular alterations of IOPN in juxtaposition with the typical molecular profile of conventional pancreatic ductal adenocarcinoma and intraductal papillary mucinous neoplasm from reference cohorts was subsequently conducted.

Molecular pathology selected abstracts

July 2025—Liver damage can result in a build up of scar tissue, or fibrosis, a hallmark of chronic liver disease (CLD). The latter has been attributed to a variety of risk factors, including viruses (primarily hepatitis B and C), obesity, and alcohol abuse. Furthermore, some patients have a genetic predisposition for the disease. Alpha-1 antitrypsin (A1AT) deficiency and hereditary hemochromatosis are two such inherited disorders that cause hepatocyte stress and damage. In A1AT deficiency, mutations in the SERPINA1 gene produce abnormal variants of the A1AT protein, which can accumulate in the liver and lead to hepatocyte damage. Mutations in the HFE gene are responsible for hereditary hemochromatosis.

Pathology informatics selected abstracts

July 2025—Computational pathology has largely focused on analyzing tissue slides and overlooked worthwhile information in gross images. Recognizing this, the authors introduced a novel deep learning model based on Swin Transformer architecture and called Swin Transformer-based Gross Features Detective Network (SGFD-network). They sought to summarize and classify the gross examination characteristics of ovarian epithelial tumors by analyzing images of gross specimens using this deep learning approach. The SGFD-network is especially useful for distinguishing borderline tumors with microinvasive components from frank carcinomas. This capability is crucial during frozen section analysis, in which limited sampling and time pressures often challenge diagnostic accuracy.

Q&A column

July 2025
Q. What is the best way to check machine precision? Is it acceptable to run precision replicates in quality control mode? Read answer.

Q. Several molecular diagnostic vendors circulate across U.S. hospitals and clinics to provide collection kits to physicians and request that those physicians refer tests outside the institution for what is sometimes described as clinical trials or research. The vendors operate using a pharmaceutical company model of selling proprietary testing directly to physicians and patients and bypassing the laboratory. It is a problem because laboratories are often expected to collect and submit samples and then enter complex reports into the electronic health record.

These companies are farming health systems for business and bypassing the accreditation process. When the testing is used not for research but instead for “the purpose of providing information for the diagnosis, prevention, or treatment of any disease or impairment of, or the assessment of the health of, human beings,” under U.S. law it is defined as laboratory testing (section 353 of the Public Health Service Act, 42 USC §263a), which is overseen by pathology laboratories and under pathology’s accreditation. Under this legal definition of laboratory testing, those outsourced tests are not research.

Can you comment on this practice from an accreditation perspective? Read answer.

Newsbytes

July 2025—PathAI and Chicago-based Northwestern Medicine have entered a multi-year venture in which Northwestern will implement PathAI’s AISight digital pathology image-management system. The two entities will also jointly undertake research initiatives and develop clinical innovation programs and artificial intelligence-powered diagnostic tools.