Cerebrospinal fluid (CSF) samples are increasingly being used for genomic profiling of brain tumors, offering a less invasive alternative to tissue biopsies. CSF samples provide a higher signal-to-noise ratio for detecting tumor-derived cell-free DNA (cfDNA) compared to plasma samples, making them particularly useful for …
The upcoming ASCO 2026 meeting will focus on the clinical application of AI in cancer care, emphasizing multimodal AI models that integrate pathology, radiology, molecular data, and liquid biopsy.
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Thermo Fisher Scientific’s SwiftArrayStudio microarray analyzer was developed in response to customer needs for simpler workflows, more consistent turnaround times, and lower operational burden in genomics labs.
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February 2026—Prepared with expert insight from Anil Parwani, MD, PhD; Scott Hammond; and Melinda Schumacher, MD, Grundium’s white paper describes, from a pathologist’s perspective, how compact WSI systems can shorten consult turnaround times and reduce variability, improve access to subspecialty review without adding travel or courier burden, enhance community pathologists’ professional satisfaction and confidence, support scalable, secure, and validated workflows and lay the foundation for AI and advanced analytics as digital adoption grows. Download the white paper here.
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Laboratory and pathology billing face challenges from reimbursement threats, downcoding, denials, and prior authorizations.
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A study integrating metabolomic, genomic, and lifestyle data identified 235 circulating metabolites linked to future type 2 diabetes risk, revealing genetic and lifestyle influences and proposing a 44-metabolite signature to enhance risk prediction; a separate retrospective cohort study found that pediatric heart transplant recipients of COVID-19–positive donor hearts had higher mortality at two and three years, especially with donor-recipient size mismatch, suggesting cautious use of such donors in pediatric transplants.
CAR T-cell therapy-related gastrointestinal toxicity presents with symptoms like abdominal pain and diarrhea, occurring 1.5 to eight months post-treatment. Histologic examination reveals a graft versus host disease-like pattern, with epithelial apoptosis and a paucity of B cells and plasma cells, necessitating careful differentiation from mimics like graft versus host disease and infection.
Summary Long-read sequencing, combined with transcriptomic profiling and functional assays, resolved six out of seven…
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April 2026—Biocartis’ Idylla CDx MSI test has received class C companion diagnostic certification under the European Union IVDR.