Webinars and Sponsored Roundtables — Register Now
Tuesday, October 20, 2026, 11 AM-12 PM ET
Hear experts review the biological and clinical significance of the HER2 expression continuum in breast tissue, providing a clearer understanding of how these variations might impact diagnosis, and discuss the emerging importance of documenting HER2-low and HER2-ultralow categories using a validated IHC assay.
Webinar presenters Keith Wharton, MD, PhD, Global Medical Affairs Leader–Pathology, Roche Diagnostics Solutions, and Hannah Y. Wen, MD, PhD, Director, Breast Pathology Fellowship, Associate Team Leader, Breast Pathology Team, Attending Pathologist, Memorial Sloan Kettering Cancer Center
CAP TODAY does not endorse any of the products or services named within. The webinar is made possible by a special educational grant from Roche.
Moderated by: Bob McGonnagle, Publisher, CAP TODAY
Thursday, October 29, 2026, 1 PM-2 PM ET
Hear an expert discuss the evolving role of PD-L1 testing in HNSCC and ovarian cancer.
Webinar presenter Georgios Deftereos, MD, Professor of Pathology, Associate Director of the Clinical Cancer Genomics Laboratory, Director of Molecular Cytopathology, University of California, San Francisco
CAP TODAY does not endorse any of the products or services named within. The webinar is made possible by a special educational grant from Agilent.
Moderated by: Bob McGonnagle, Publisher, CAP TODAY
Tuesday, November 3, 2026, 1 PM-2 PM ET
Hear an expert discuss the challenges of detecting NRG1 fusions and how RNA-based testing can support more comprehensive fusion identification in clinical practice.
Webinar presenter Benjamin Weinberg, MD, Associate Professor of Medicine and Attending Physician
specializing in gastrointestinal medical oncology
CAP TODAY does not endorse any of the products or services named within. The webinar is made possible by a special educational grant from Diaceutics.
Moderated by: Bob McGonnagle, Publisher, CAP TODAY
Tuesday, November 10, 2026, 1 PM-2 PM ET
Join us for a session to help improve diagnostic accuracy in your practice when scoring HER2 IHC 0 with faint, incomplete membrane staining in ≤10% of tumor cells vs IHC 0 with no membrane staining detected in patients with mBC.
Webinar presenter Jeffrey Gregg, MD, University of Nevada
CAP TODAY does not endorse any of the products or services named within. This program is being sponsored by Daiichi Sankyo, Inc. and AstraZeneca. The speaker is being compensated for the presentation. The program is not CME accredited and may not be used for CME accreditation.
Moderated by: Bob McGonnagle, Publisher, CAP TODAY
Monday, November 16, 2026, 12:30 PM-2 PM ET
Hear experts discuss a multidisciplinary approach to oncopathology for HER2
assessments for solid tumors in the absence of a companion diagnostic.
Webinar presenters Funda Meric-Bernstam, MD, Chair, Department of Investigational Cancer Therapeutics Medical Director, Institute for Personalized Cancer Therapy, The University of Texas MD Anderson Cancer Center, Houston, Texas, and Emina E. Torlakovic, MD, PhD, College of Medicine, University of Saskatchewan, Canadian Biomarker Quality Assurance, Saskatoon, Saskatchewan, Canada, and Carol Cheung, MD, PhD, JD, FRCPC, Deputy Director, Canadian Biomarker Quality, Assurance—Programme canadien d’assurance de la qualité des biomarqueurs
CAP TODAY does not endorse any of the products or services named within. This program is being sponsored by Daiichi Sankyo, Inc. and AstraZeneca. The speaker is being compensated for the presentation. The program is not CME accredited and may not be used for CME accreditation.
Moderated by: Bob McGonnagle, Publisher, CAP TODAY
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Product Spotlight
Illumina
| Company | Illumina |
|---|---|
| Name of system | MiSeq i100 |
| City, State | San Diego, CA |
| Phone | 858-202-4500 |
| Website | |
| System application/FDA cleared or approved | research use/not required |
| Country where designed/Manufactured | U.S./Singapore |
| First year sold in U.S./First year installed in U.S. | 2025/2025 |
| System sold internationally | yes (worldwide) |
| Dimensions of sequencer (H × W × D)/Footprint of sequencer | 25.6 × 15.8 × 17.6 in./1.9 sq. ft. |
| Accessory equipment supplied with sequencer at no cost | — |
| Type of computer supplied with sequencer | computer for analysis and operations combined |
| Analysis options provided with sequencer | onboard, cloud based |
| Where library preparation is performed | wet bench |
| Bioinformatics tools provided with sequencer | DRAGEN Bio-IT, BaseSpace Sequence Hub, Illumina Connected Analytics |
| Sequencer supplied with UPS (uninterruptible power supply) | no |
| Electrical connection required for sequencer | 100–240 at VAC 50/60 Hz, 300 W, single phase |
| List price of entire sequencer and necessary components | $49, 900 |
| Purchase options | purchase, lease, reagent rental |
| Warranties offered | — |
| Training included/Total time for basic training per operator | no/2 days |
| Training location/Follow-up training available | at vendor office or customer site/yes (extra charge) |
| Maximum No. of samples amplified in a single amplification event | 384 samples |
| Read length/Percent bases >Q30 | up to 2 × 300 bp/85% (for 2 × 300 bp) |
| Paired-end capability/Tag lengths/Spans | yes/up to 2 × 500 bp/950 bp |
| Fragment/Tag lengths/Spans | yes/up to 2 × 300 bp/— |
| Mate pair/Tag lengths/Spans | yes/up to 2 × 150 bp/— |
| Single end/Tag lengths/Spans | yes/up to 1 × 300 bp/— |
| RNA sequencing/Tag lengths/Spans | yes/up to 2 × 300 bp/— |
| ChIP sequencing/Tag lengths/Spans | yes/up to 2 × 300 bp/— |
| Bisulfite sequencing/Tag lengths/Spans | yes/up to 2 × 300 bp/— |
| Maximum No. of reads or fragments sequenced per single-end run | 25 million |
| Maximum No. of reads or fragments sequenced per paired-end run | 50 million |
| Total No. of nucleotides (bases) sequenced per run | 25 Gb |
| Wet lab bench time for sequencing preparation | 10 minutes |
| Sequencing run time | ~4–24 hours |
| Total time for generating standard gDNA library | <3.5 hours (with Illumina DNA Prep) |
| • Paired end | <3.5 hours (with Illumina DNA Prep) |
| • Fragment | <7 hours (with AmpliSeq for Illumina); <6.5 hours with Illumina DNA Prep with Enrichment) |
| • Mate pair | — |
| • Single end | <1 day (with TruSeq Small RNA) |
| • RNA sequencing | <9 hours |
| • Bisulfite sequencing | — |
| • Hands-on time for paired end | <1.5 hours (with Illumina DNA Prep) |
| • Hands-on time for fragment | <1.5 hours (with AmpliSeq for Illumina); <2 hours (with Illumina DNA Prep with Enrichment) |
| • Hands-on time for mate pair | — |
| • Hands-on time for single end | <4 hours (with TruSeq Small RNA) |
| • Hands-on time for RNA sequencing | <3 hours |
| • Hands-on time for ChIP sequencing | — |
| • Hands-on time for bisulfite sequencing | — |
| Library preparation integrated in system as standard offering | no |
| Cost of sequencing reagents per run | $420–$1,700 |
| Reagent tracking method | RFID |
| • Type of reagent information tracked | serial No., expiration date, lot and part Nos., No. of cycles |
| Shipping conditions for amplification/sequencing reagents | room temperature/room temperature |
| Storage conditions for amplification/sequencing reagents | room temperature/room temperature |
| Shelf life of amplification/sequencing reagents | guaranteed 3 months/guaranteed 3 months |
| System requires a control sample on sequencing run | optional |
| • Company offers a sequencing control | yes (additional charge) |
| Sequencing system control software and devices to start run/for data analysis | MiSeq i100 Control Software/BaseSpace Sequence Hub, DRAGEN secondary analysis |
| Complete walkaway automation for amplification, sequencing, and variant calling | yes |
| Remote system monitoring | yes |
| Total time required for setup of amplification, sequencing, and variant calling steps | 10 minutes |
| Maximum No. of libraries sequenced in a single run | 384 samples |
| System includes secondary data-analysis software developed by company | yes (DRAGEN, BaseSpace Sequence Hub) |
| System includes post-sequencing data-analysis software | yes (DRAGEN) |
| Mutations detectable via data-analysis software | substitutions, indels, copy number changes |
| System can generate a variant report | yes |
| Types of maintenance plans available/mean time between failures | parts only, bronze, silver, gold, Dx, dedicated on-site/— |
| No. of field application scientists and engineers based in U.S. | >500 |
| • Weekly maintenance required | none |
| • Monthly maintenance required | none |
| • Pre-run maintenance required | none |
| Distinguishing features of NGS system (supplied by company) | room temperature shipping and storage of sequencing consumables; automated onboard flow-cell denaturation, onboard cluster generation, no post-run washing; simplified data analysis with access to preconfigured DRAGEN pipelines onboard or in the cloud, minimizing the need for bioinformatics expertise |