Webinars and Sponsored Roundtables — Register Now

Wednesday, September 23, 2026. 12 PM-1 PM ET
Roundtable presenters Dr. David Sacks MB, ChB, FRCPath, Chairman, Steering Committee National Glycohemoglobin Standardization Program (NGSP), and Priya Sivaraman, PhD, Senior Technical Product Manager, Tosoh Bioscience.

Moderated by: Bob McGonnagle, Publisher, CAP TODAY

Thursday, September 24, 2026 11 AM-12 PM CT
This session explores the evolving role of RAS in precision oncology, from the biology of RAS mutations to the expanding landscape of targeted therapies. Through expert presentations, real-world case discussions, and interactive audience polling, participants will examine best practices for RAS biomarker testing across solid tumors, including lung, colorectal, and pancreatic cancers. The session will highlight practical considerations for tissue and liquid biopsy, strategies to address testing gaps, and the importance of multidisciplinary collaboration to ensure timely identification of patients who may benefit from RAS-targeted therapies.

Webinar presenters David Braxton, MD, Chief of Molecular Pathology Services, Hoag Family Cancer Institute & Hoag Memorial Hospital Presbyterian, and Carlos Becerra, MD, Research Director for Medical Oncology, Margaret Given Larkin Endowed Chair for Developmental Cancer Therapeutics, Hoag Memorial Hospital Presbyterian.

Moderated by: Bob McGonnagle, Publisher, CAP TODAY

Wednesday, September 30, 2026. 1 PM-1:30 PM ET
Roundtable presenters John Longshore, PhD, Head of Scientific Affairs, Global Oncology Diagnostics, AstraZeneca, and Flora Berisha, MS, Executive Director, Global Head of Diagnostic Partnering and Development, Johnson & Johnson Innovative Medicine, and Mark D. Ewalt, MD, Associate Medical Director for Laboratory Operations, Diagnostic Molecular Pathology, Molecular Diagnostics Service, Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, and Isabel Preeshagul, DO, MBS, Thoracic Medical Oncologist, Memorial Sloan Kettering Cancer Center.

Moderated by: Bob McGonnagle, Publisher, CAP TODAY

Tuesday, October 20, 2026 11 AM-12 PM ET
Hear experts review the biological and clinical significance of the HER2 expression continuum in breast tissue, providing a clearer understanding of how these variations might impact diagnosis, and discuss the emerging importance of documenting HER2-low and HER2-ultralow categories using a validated IHC assay.

Webinar presenters Keith Wharton, MD, PhD, Global Medical Affairs Leader–Pathology,
Roche Diagnostics Solutions, and Hannah Y. Wen, MD, PhD, Director, Breast Pathology Fellowship, Associate Team Leader, Breast Pathology Team, Attending Pathologist, Memorial Sloan Kettering Cancer Center.

Moderated by: Bob McGonnagle, Publisher, CAP TODAY

Subspecialties

Interactive Product Guides

Product Spotlight

Illumina

NovaSeq X; NovaSeq X Plus

Company

Illumina

Name of system

NovaSeq X; NovaSeq X Plus

Email

info@illumina.com

City, State

San Diego, CA

Phone

858-202-4500  

Website

http://www.illumina.com

System application/FDA cleared or approved

research use/not required

Country where designed/Manufactured

U.S./U.S.

First year sold in U.S./First year installed in U.S.

2022/2023

System sold internationally

yes (worldwide)

Dimensions of sequencer (H × W × D)/Footprint of sequencer

62.5 × 34 × 36.7 in./8.7 sq. ft.

Accessory equipment supplied with sequencer at no cost

Type of computer supplied with sequencer

computer for analysis and operations combined

Analysis options provided with sequencer

onboard, cluster based, cloud based

Where library preparation is performed

wet bench

Bioinformatics tools provided with sequencer

DRAGEN Bio-IT platform, Illumina Run Manager, BaseSpace Sequence Hub

Sequencer supplied with UPS (uninterruptible power supply)

yes (no extra charge)

Electrical connection required for sequencer

200–240 VAC at 50/60 Hz

List price of entire sequencer and necessary components

NovaSeq X: $985,000; NovaSeq X Plus: $1,250,000

Purchase options

purchase, trade in, lease, reagent rental

Warranties offered

first year included with purchase; extended warranty available

Training included/Total time for basic training per operator

yes/2 days

Training location/Follow-up training available

at customer site/yes (extra charge)

Maximum No. of samples amplified in a single amplification event

384 samples (>384 samples with custom barcodes)

Read length/Percent bases >Q30

up to 2 × 300 bp/85–90%

Paired-end capability/Tag lengths/Spans

yes/up to 2 × 300 bp/—

Fragment/Tag lengths/Spans

yes/2 × 150 bp/—

Mate pair/Tag lengths/Spans

yes/2 × 150 bp/—

Single end/Tag lengths/Spans

yes/2 × 150 bp/—

RNA sequencing/Tag lengths/Spans

yes/2 × 150 bp/—

ChIP sequencing/Tag lengths/Spans

yes/2 × 150 bp/—

Bisulfite sequencing/Tag lengths/Spans

yes/2 × 150 bp/—

Maximum No. of reads or fragments sequenced per single-end run

~52–70 billion 

Maximum No. of reads or fragments sequenced per paired-end run

~104–140 billion

Total No. of nucleotides (bases) sequenced per run

~8,000–21,000 Gb

Wet lab bench time for sequencing preparation

10 minutes

Sequencing run time

~13–48 hours

Total time for generating standard gDNA library

<3.5 hours (with Illumina DNA Prep)

• Paired end

<3.5 hours (with Illumina DNA Prep)

• Fragment

<7 hours (with AmpliSeq for Illumina); <6.5 hours (with Illumina DNA Prep with Enrichment)

• Mate pair

• Single end

<1 day (with TruSeq Small RNA)

• RNA sequencing

<9 hours

• Bisulfite sequencing

• Hands-on time for paired end

<1.5 hours (with Illumina DNA Prep)

• Hands-on time for fragment

<1.5 hours (with AmpliSeq for Illumina); <2 hours (with Illumina DNA Prep with Enrichment)

• Hands-on time for mate pair

• Hands-on time for single end

<4 hours (with TruSeq Small RNA)

• Hands-on time for RNA sequencing

<3 hours

• Hands-on time for ChIP sequencing

• Hands-on time for bisulfite sequencing

Library preparation integrated in system as standard offering

no

Cost of sequencing reagents per run

$2,006–$16,892

Reagent tracking method

RFID

• Type of reagent information tracked

serial No., expiration date, lot and part Nos., No. of cycles

Shipping conditions for amplification/sequencing reagents

—/ambient

Storage conditions for amplification/sequencing reagents

—/reagent cartridge, preload buffer, lyo insert: -15°– -25°C; flow cell: 2°–8°C; library tube strip, buffer cartridge: 15°– 30°C

Shelf life of amplification/sequencing reagents

—/guaranteed 3 months

System requires a control sample on sequencing run 

optional

• Company offers a sequencing control

yes (additional charge)

Sequencing system control software and devices to start run/for data analysis

NovaSeq X, X Plus Control Software/BaseSpace Sequence Hub, DRAGEN

Complete walkaway automation for amplification, sequencing, and variant calling

yes

Remote system monitoring

yes

Total time required for setup of amplification, sequencing, and variant calling steps

5–30 minutes

Maximum No. of libraries sequenced in a single run

384 samples (>384 samples with custom barcodes)

System includes secondary data-analysis software developed by company

yes (DRAGEN, BaseSpace Sequence Hub)

System includes post-sequencing data-analysis software

yes (DRAGEN)

Mutations detectable via data-analysis software

substitutions, indels, copy number changes

System can generate a variant report

yes

Types of maintenance plans available/mean time between failures

parts only, bronze, silver, gold, dedicated on-site/—

No. of field application scientists and engineers based in U.S.

>500

• Weekly maintenance required

none (maintenance wash every 2 weeks)

• Monthly maintenance required

none

• Pre-run maintenance required

none

Distinguishing features of NGS system (supplied by company)

automated onboard cluster generation and secondary anlaysis with DRAGEN; ambient shipping of sequencing consumables; configurable sequencing method, flow-cell type, and read length to support a broad range of applications

More products
in this guide

MiSeq i100 Plus
NextSeq 550Dx
NextSeq 1000; NextSeq 2000
NovaSeq 6000Dx
Ion GeneStudio S5 System
Ion Torrent Genexus Integrated Sequencer; Ion Torrent Genexus Dx Integrated Sequencer