Webinars and Sponsored Roundtables — Register Now
Tuesday, June 9, 2026, 1:00–2:00 PM ET
In this webinar, we will examine how immune recognition after allogeneic HCT can influence leukemia relapse and disease progression. The session will highlight the clinical relevance of HLA loss of heterozygosity (LOH), approaches used for its detection, and how LOH findings may support transplant strategies, including considerations for donor selection in subsequent transplantation.
Webinar presenter Alberto Cardoso Martins Lima, PhD, Clinical consulting scientist in histocompatibility,
specializing in allogeneic hematopoietic cell transplantation (HCT) at IGEN/AFIP São Paulo and CHC/UFPR in Curitiba, Brazil
Moderated by: Bob McGonnagle, Publisher, CAP TODAY
Wednesday, June 24, 2026, 12:00–1:00 PM ET
Hear an expert discuss the expanded clinical utility of HER2 IHC scoring in metastatic breast cancer and its impact on your practice
Webinar presenter Michelle Shiller, DO, AP, CP, MGP, FACP, Baylor University Medical Center.
Moderated by: Bob McGonnagle, Publisher, CAP TODAY
Wednesday, July 15, 2026, 1:00-2:00 PM ET
Hear an expert discuss how to integrate Kappa and Lambda in situ hybridization testing into your standard hematopathology workflow to accurately assess B-cell and plasma cell clonality. You will also gain the skills to recognize testing pitfalls in challenging reactive versus neoplastic proliferations and apply ancillary tools to resolve complex cases.
Webinar presenter Xiaojun Wu, MD, PhD, Assistant professor, Director of Hematopathology Section at NCR of Johns Hopkins Medicine Department of Pathology, SOM at Johns Hopkins University
Moderated by: Bob McGonnagle, Publisher, CAP TODAY
Interactive Product Guides
Product Spotlight
Thermo Fisher Scientific
Ion Torrent Genexus Integrated Sequencer; Ion Torrent Genexus Dx Integrated Sequencer
| Company | Thermo Fisher Scientific |
|---|---|
| Name of system | Ion Torrent Genexus Integrated Sequencer; Ion Torrent Genexus Dx Integrated Sequencer |
| City, State | Carlsbad, CA |
| Phone | 800-955-6288 |
| Website | |
| System application/FDA cleared or approved | Genexus: research use; Genexus Dx: in vitro diagnostic and research use/not required |
| Country where designed/Manufactured | U.S./Singapore |
| First year sold in U.S./First year installed in U.S. | Genexus: 2019/2019; Genexus Dx: 2025/2025 |
| System sold internationally | Genexus: yes (worldwide); Genexus Dx: yes (multiple countries) |
| Dimensions of sequencer (H × W × D)/Footprint of sequencer | open: 81.1 × 58.5 × 43.5 in.; closed: 66.1 × 41.9 × 32.1 in./open: 17.67 sq. ft.; closed: 9.36 sq. ft. |
| Accessory equipment supplied with sequencer at no cost | none |
| Type of computer supplied with sequencer | computer for analysis |
| Analysis options provided with sequencer | onboard, cloud based |
| Where library preparation is performed | sequencer |
| Bioinformatics tools provided with sequencer | Ion Torrent Genexus Software (optional: Oncomine Reporter) |
| Sequencer supplied with UPS (uninterruptible power supply) | no |
| Electrical connection required for sequencer | 100–240 VAC |
| List price of entire sequencer and necessary components | — |
| Purchase options | purchase, trade in, lease, reagent rental, finance |
| Warranties offered | first year included with purchase; extended warranty avail. |
| Training included/Total time for basic training per operator | yes/2 days |
| Training location/Follow-up training available | at customer site/yes (extra charge) |
| Maximum No. of samples amplified in a single amplification event | 48 samples on system, 96 samples off instr. (for library prep) |
| Read length/Percent bases >Q30 | up to 400 bp/— |
| Paired-end capability/Tag lengths/Spans | — |
| Fragment/Tag lengths/Spans | — |
| Mate pair/Tag lengths/Spans | — |
| Single end/Tag lengths/Spans | yes/—/up to 400 bp |
| RNA sequencing/Tag lengths/Spans | — |
| ChIP sequencing/Tag lengths/Spans | — |
| Bisulfite sequencing/Tag lengths/Spans | — |
| Maximum No. of reads or fragments sequenced per single-end run | 48–60 million at 200–400 bp (GX5, GX5 Dx); 80–100 million at 200 bp (GX7) |
| Maximum No. of reads or fragments sequenced per paired-end run | — |
| Total No. of nucleotides (bases) sequenced per run | 9.6–12 Gb at 200 bp (GX5, GX5 Dx); 16–20 Gb at 200 bp (GX7) |
| Wet lab bench time for sequencing preparation | 10 minutes |
| Sequencing run time | 19–24 hours (includes automated library prep) |
| Total time for generating standard gDNA library | — |
| • Paired end | — |
| • Fragment | — |
| • Mate pair | — |
| • Single end | — |
| • RNA sequencing | — |
| • Bisulfite sequencing | — |
| • Hands-on time for paired end | — |
| • Hands-on time for fragment | — |
| • Hands-on time for mate pair | — |
| • Hands-on time for single end | — |
| • Hands-on time for RNA sequencing | — |
| • Hands-on time for ChIP sequencing | — |
| • Hands-on time for bisulfite sequencing | — |
| Library preparation integrated in system as standard offering | yes (AmpliSeq, AmpliSeq HD) |
| Cost of sequencing reagents per run | — |
| Reagent tracking method | RFID, barcode reader |
| • Type of reagent information tracked | expiration date, lot and part Nos., placement |
| Shipping conditions for amplification/sequencing reagents | -20°C, 4°C, ambient (variable based on product)/-20°C, 4°C, ambient (variable based on product) |
| Storage conditions for amplification/sequencing reagents | -20°C, 4°C, ambient (variable based on product)/-20°C, 4°C, ambient (variable based on product) |
| Shelf life of amplification/sequencing reagents | 12–36 months from manufacture date (variable based on product)/12–36 months from manufacture date (variable based on product) |
| System requires a control sample on sequencing run | optional |
| • Company offers a sequencing control | yes (additional charge) |
| Sequencing system control software and devices to start run/for data analysis | Ion Torrent Genexus Software/Genexus Software, Oncomine Reporter |
| Complete walkaway automation for amplification, sequencing, and variant calling | yes |
| Remote system monitoring | yes |
| Total time required for setup of amplification, sequencing, and variant calling steps | 10 minutes |
| Maximum No. of libraries sequenced in a single run | 48 samples or 96 libraries |
| System includes secondary data-analysis software developed by company | yes (Ion Reporter, Oncomine Reporter) |
| System includes post-sequencing data-analysis software | yes (Genexus: Genexus Software, Oncomine Reporter;Genexus Dx: Genexus Dx Software, Oncomine Reporter) |
| Mutations detectable via data-analysis software | substitutions, indels, copy number changes, fusions |
| System can generate a variant report | yes |
| Types of maintenance plans available/mean time between failures | AB Assurance, AB Platinum NGS (Dx plans also avail.)/— |
| No. of field application scientists and engineers based in U.S. | 450 |
| • Weekly maintenance required | none |
| • Monthly maintenance required | none |
| • Pre-run maintenance required | none |
| Distinguishing features of NGS system (supplied by company) | Dx sequencer is a CE-IVD-marked, FDA-listed class II IVD medical device; walkaway automation of NGS workflow, incl. library prep, sequencing, analysis, reporting; start with as little as 1 ng of input DNA or RNA; scalable plug-and-play reagent architecture allows for cost-efficient sequencing of small and large batches |