Webinars and Sponsored Roundtables — Register Now

Thursday, May 28, 2026, 1:00–2:00 PM ET
This session is designed to improve understanding and application of recent updates to synoptic pathology reporting protocols such as the latest Reporting Template for Reporting Results of Biomarker Testing of Specimens from Patients with Carcinoma of the Breast. These changes reflect evolving clinical guidelines that directly influence diagnostic accuracy and treatment selection in breast cancer care.

Webinar presenters Thaer Khoury, MD, FCAP, Chair, Pathology and Laboratory Medicine, Roswell Park Comprehensive Cancer Cente, and Colin Murphy,  CEO of mTuitive.

Moderated by: Bob McGonnagle, Publisher, CAP TODAY

Tuesday, June 9, 2026, 1:00–2:00 PM ET
In this webinar, we will examine how immune recognition after allogeneic HCT can influence leukemia relapse and disease progression. The session will highlight the clinical relevance of HLA loss of heterozygosity (LOH), approaches used for its detection, and how LOH findings may support transplant strategies, including considerations for donor selection in subsequent transplantation.

Webinar presenter Alberto Cardoso Martins Lima, PhD, Clinical consulting scientist in histocompatibility,
specializing in allogeneic hematopoietic cell transplantation (HCT) at IGEN/AFIP São Paulo and CHC/UFPR in Curitiba, Brazil

Moderated by: Bob McGonnagle, Publisher, CAP TODAY

Wednesday, June 24, 2026, 12:00–1:00 PM ET
Hear an expert discuss the expanded clinical utility of HER2 IHC scoring in metastatic breast cancer and its impact on your practice

Webinar presenter Michelle Shiller, DO, AP, CP, MGP, FACP, Baylor University Medical Center.

Moderated by: Bob McGonnagle, Publisher, CAP TODAY

Subspecialties

Interactive Product Guides

Product Spotlight

Illumina

NovaSeq 6000Dx

Company

Illumina

Name of system

NovaSeq 6000Dx

Email

info@illumina.com

City, State

San Diego, CA

Phone

858-202-4500  

Website

http://www.illumina.com

System application/FDA cleared or approved

in vitro diagnostic and research use/yes

Country where designed/Manufactured

U.S./U.S.

First year sold in U.S./First year installed in U.S.

2022/2022

System sold internationally

yes (worldwide)

Dimensions of sequencer (H × W × D)/Footprint of sequencer

65.2 × 31.5 × 37.2 in./8.2 sq. ft.

Accessory equipment supplied with sequencer at no cost

Illumina DRAGEN server for NovaSeq 6000Dx

Type of computer supplied with sequencer

computer for analysis and operations combined

Analysis options provided with sequencer

onboard, cluster based, cloud based

Where library preparation is performed

wet bench

Bioinformatics tools provided with sequencer

DRAGEN Bio-IT platform, Illumina Run Manager, BaseSpace Sequence Hub

Sequencer supplied with UPS (uninterruptible power supply)

yes (no extra charge)

Electrical connection required for sequencer

200–240 VAC at 50/60 Hz, 16 A, single phase, 2500 W

List price of entire sequencer and necessary components

$850, 000

Purchase options

purchase, lease, reagent rental

Warranties offered

first year included with purchase; extended warranty available

Training included/Total time for basic training per operator

yes/2 days

Training location/Follow-up training available

at customer site/yes (extra charge)

Maximum No. of samples amplified in a single amplification event

384 samples (>384 samples with custom barcodes)

Read length/Percent bases >Q30

1 × 35–2 × 250 bp/90% (1 × 35 bp, 2 × 50 bp); 85% (2 × 200 bp, 2 × 150 bp); 75% (2 × 250 bp)

Paired-end capability/Tag lengths/Spans

yes/up to 2 × 250 bp/up to 550 bp

Fragment/Tag lengths/Spans

yes/up to 2 × 250 bp/up to 550 bp

Mate pair/Tag lengths/Spans

yes/up to 2 × 250 bp/2–12 kb

Single end/Tag lengths/Spans

yes/up to 1 × 300 bp/up to 350 bp

RNA sequencing/Tag lengths/Spans

yes/up to 2 × 250 bp/up to 500 bp

ChIP sequencing/Tag lengths/Spans

yes/up to 2 × 250 bp/up to 550 bp

Bisulfite sequencing/Tag lengths/Spans

yes/up to 2 × 250 bp/up to 550 bp

Maximum No. of reads or fragments sequenced per single-end run

up to 20 billion

Maximum No. of reads or fragments sequenced per paired-end run

up to 40 billion

Total No. of nucleotides (bases) sequenced per run

up to 6,000 Gb per run, 3,000 Gb per flow cell

Wet lab bench time for sequencing preparation

10 minutes

Sequencing run time

<45 hours

Total time for generating standard gDNA library

<3.5 hours (with Illumina DNA Prep)

• Paired end

<3.5 hours (with Illumina DNA Prep)

• Fragment

<7 hours (with AmpliSeq for Illumina); <6.5 hours (with Illumina DNA Prep with Enrichment)

• Mate pair

• Single end

<1 day (with TruSeq Small RNA)

• RNA sequencing

<9 hours

• Bisulfite sequencing

• Hands-on time for paired end

<1.5 hours (with Illumina DNA Prep)

• Hands-on time for fragment

<1.5 hours (with AmpliSeq for Illumina); <2 hours (with Illumina DNA Prep with Enrichment)

• Hands-on time for mate pair

• Hands-on time for single end

<4 hours (with TruSeq Small RNA)

• Hands-on time for RNA sequencing

<3 hours

• Hands-on time for ChIP sequencing

• Hands-on time for bisulfite sequencing

Library preparation integrated in system as standard offering

no

Cost of sequencing reagents per run

$2,490–$17,324

Reagent tracking method

RFID

• Type of reagent information tracked

serial No., expiration date, lot and part Nos., No. of cycles

Shipping conditions for amplification/sequencing reagents

—/dry ice, gel pack, ambient (variable based on product)

Storage conditions for amplification/sequencing reagents

—/cluster, SBS cartridges: -15°– -25°C; flow cell: 2°– 8°C; buffer cartridge: 15°– 30°C

Shelf life of amplification/sequencing reagents

—/up to 24 months

System requires a control sample on sequencing run 

optional

• Company offers a sequencing control

yes (additional charge)

Sequencing system control software and devices to start run/for data analysis

—/BaseSpace Sequence Hub, DRAGEN

Complete walkaway automation for amplification, sequencing, and variant calling

yes

Remote system monitoring

yes

Total time required for setup of amplification, sequencing, and variant calling steps

5–30 minutes

Maximum No. of libraries sequenced in a single run

384 samples (>384 samples with custom barcodes)

System includes secondary data-analysis software developed by company

yes (Illumina Run Manager)

System includes post-sequencing data-analysis software

yes (Illumina Run Manager)

Mutations detectable via data-analysis software

substitutions, indels, copy number changes

System can generate a variant report

yes

Types of maintenance plans available/mean time between failures

gold, silver, bronze/—

No. of field application scientists and engineers based in U.S.

>500

• Weekly maintenance required

none (maintenance wash every 2 weeks)

• Monthly maintenance required

• Pre-run maintenance required

Distinguishing features of NGS system (supplied by company)

more samples and deeper sequencing from diagnostic testing to clinical research; flexible RUO and IVD modes with scalable sequencing power; accurate, efficient data analysis; high-quality data with a paired, dedicated DRAGEN server; reduce time to answer; reimagined user interface with a simple workflow

More products
in this guide

MiSeq i100 Plus
NextSeq 550Dx
NextSeq 1000; NextSeq 2000
NovaSeq X; NovaSeq X Plus
Ion GeneStudio S5 System
Ion Torrent Genexus Integrated Sequencer; Ion Torrent Genexus Dx Integrated Sequencer