Webinars and Commercial Conversations — Register Now

Tuesday, November 10, 2026, 1:00 PM-2 PM ET
Join us for a session to help improve diagnostic accuracy in your practice when scoring HER2 IHC 0 with faint, incomplete membrane staining in ≤10% of tumor cells vs IHC 0 with no membrane staining detected in patients with mBC.

Webinar presenter Samuel Caughron, MD, FCAP, Chief Strategy Officer, MAWD Pathology, Medical Director of Laboratory, AdventHealth Kansas City, Medical Director of Laboratory, Labcorp, President, Member & Director, Pathology Ventures, LLC

CAP TODAY does not endorse any of the products or services named within. This program is intended for US healthcare professionals. This program is being sponsored by AstraZeneca. The speaker is being compensated for the presentation. The program is not CME accredited and may not be used for CME accreditation.

Moderated by: Bob McGonnagle, Publisher, CAP TODAY

Monday, November 16, 2026, 12:30 PM-2 PM ET
Hear experts discuss a multidisciplinary approach to oncopathology for HER2
assessments for solid tumors in the absence of a companion diagnostic.

Webinar presenters Funda Meric-Bernstam, MD, Chair, Department of Investigational Cancer Therapeutics Medical Director, Institute for Personalized Cancer Therapy, The University of Texas MD Anderson Cancer Center, Houston, Texas, and Emina E. Torlakovic, MD, PhD, College of Medicine, University of Saskatchewan, Canadian Biomarker Quality Assurance, Saskatoon, Saskatchewan, Canada, and Carol Cheung, MD, PhD, JD, FRCPC, Deputy Director, Canadian Biomarker Quality, Assurance—Programme canadien d’assurance de la qualité des biomarqueurs

CAP TODAY does not endorse any of the products or services named within. This program is being sponsored by Daiichi Sankyo, Inc. and AstraZeneca. The speaker is being compensated for the presentation. The program is not CME accredited and may not be used for CME accreditation.

Moderated by: Bob McGonnagle, Publisher, CAP TODAY

Wednesday, November 18, 2026, 12:00 PM-1 PM ET
Join leading pathology experts, Savitri Krishnamurthy, MD, and Marilyn Bui, MD, PhD, for a webinar exploring potential challenges in HER2 IHC testing for breast cancer, emerging evidence supporting digital and computational pathology as assistive tools for pathologists in HER2 IHC assessment, and practical considerations for real-world implementation and adoption.

Webinar presenters Savitri Krishnamurthy, MD, Professor of Pathology, Department of Anatomical Pathology The University of Texas MD Anderson Cancer Center, Houston, Texas, and Marilyn Bui, MD, PhD, Surgical Pathologist and Cytopathologist Member and Professor, Departments of Pathology, Machine Learning, and Translational Pathology, Scientific Director, Analytic Microscopy Core Chair, Women in Oncology Executive Board Moffitt Cancer Center, Tampa, Florida

CAP TODAY does not endorse any of the products or services named within. This program is being sponsored by Daiichi Sankyo, Inc. and AstraZeneca. The speakers are being compensated for their presentations. The program is not CME accredited and may not be used for CME credit.

Moderated by: Bob McGonnagle, Publisher, CAP TODAY

Wednesday, December 9, 2026, 12 PM-1 PM ET
Hear an expert pathologist discuss the role of HER2 IHC testing and scoring in solid tumors including endometrial, ovarian, cervical, bladder, non-small cell lung, colorectal, and biliary cancers

Webinar presenter Michelle Shiller, DO, MSPT, Baylor Sammons Cancer Center; Fulgent Genetics; Texas Cancer Interception Institute

CAP TODAY does not endorse any of the products or services named within. This program is intended for US healthcare professionals. This program is being sponsored by AstraZeneca. The speaker is being compensated for the presentation. The program is not CME accredited and may not be used for CME accreditation.

Moderated by: Bob McGonnagle, Publisher, CAP TODAY

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Product Spotlight

Illumina

MiSeq i100 Plus

Company

Illumina

Name of system

MiSeq i100 Plus

Email

info@illumina.com

City, State

San Diego, CA

Phone

858-202-4500  

Website

http://www.illumina.com

System application/FDA cleared or approved

research use/not required

Country where designed/Manufactured

U.S./Singapore

First year sold in U.S./First year installed in U.S.

2024/2024

System sold internationally

yes (worldwide)

Dimensions of sequencer (H × W × D)/Footprint of sequencer

25.6 × 15.8 × 17.6 in./1.9 sq. ft.

Accessory equipment supplied with sequencer at no cost

—

Type of computer supplied with sequencer

computer for analysis and operations combined

Analysis options provided with sequencer

onboard, cloud based

Where library preparation is performed

wet bench

Bioinformatics tools provided with sequencer

DRAGEN Bio-IT, BaseSpace Sequence Hub, Illumina Connected Analytics

Sequencer supplied with UPS (uninterruptible power supply)

no

Electrical connection required for sequencer

100–240 at VAC 50/60 Hz, 300 W, single phase

List price of entire sequencer and necessary components

$109, 900

Purchase options

purchase

Warranties offered

—

Training included/Total time for basic training per operator

no/2 days

Training location/Follow-up training available

at vendor office or customer site/yes (extra charge)

Maximum No. of samples amplified in a single amplification event

384 samples

Read length/Percent bases >Q30

up to 2 × 300 bp/85% (for 2 × 300 bp)

Paired-end capability/Tag lengths/Spans

yes/up to 2 × 500 bp/950 bp

Fragment/Tag lengths/Spans

yes/up to 2 × 300 bp/—

Mate pair/Tag lengths/Spans

yes/up to 2 × 150 bp/—

Single end/Tag lengths/Spans

yes/up to 1 × 300 bp/—

RNA sequencing/Tag lengths/Spans

yes/up to 2 × 300 bp/—

ChIP sequencing/Tag lengths/Spans

yes/up to 2 × 300 bp/—

Bisulfite sequencing/Tag lengths/Spans

yes/up to 2 × 300 bp/—

Maximum No. of reads or fragments sequenced per single-end run

100 million

Maximum No. of reads or fragments sequenced per paired-end run

200 million

Total No. of nucleotides (bases) sequenced per run

30 Gb

Wet lab bench time for sequencing preparation

10 minutes

Sequencing run time

~4–24 hours

Total time for generating standard gDNA library

<3.5 hours (with Illumina DNA Prep)

• Paired end

<3.5 hours (with Illumina DNA Prep)

• Fragment

<7 hours (with AmpliSeq for Illumina); <6.5 hours (withIllumina DNA Prep with Enrichment)

• Mate pair

—

• Single end

<1 day (with TruSeq Small RNA)

• RNA sequencing

<9 hours

• Bisulfite sequencing

—

• Hands-on time for paired end

<1.5 hours (with Illumina DNA Prep)

• Hands-on time for fragment

<1.5 hours (with AmpliSeq for Illumina); <2 hours (with Illumina DNA Prep with Enrichment)

• Hands-on time for mate pair

—

• Hands-on time for single end

<4 hours (with TruSeq Small RNA)

• Hands-on time for RNA sequencing

<3 hours

• Hands-on time for ChIP sequencing

—

• Hands-on time for bisulfite sequencing

—

Library preparation integrated in system as standard offering

no

Cost of sequencing reagents per run

$420–$1,700

Reagent tracking method

RFID

• Type of reagent information tracked

serial No., expiration date, lot and part Nos., No. of cycles

Shipping conditions for amplification/sequencing reagents

room temperature/room temperature

Storage conditions for amplification/sequencing reagents

room temperature/room temperature

Shelf life of amplification/sequencing reagents

guaranteed 3 months/guaranteed 3 months

System requires a control sample on sequencing run 

optional

• Company offers a sequencing control

yes (additional charge)

Sequencing system control software and devices to start run/for data analysis

MiSeq i100 Control Software/BaseSpace Sequence Hub, DRAGEN secondary analysis

Complete walkaway automation for amplification, sequencing, and variant calling

yes

Remote system monitoring

yes

Total time required for setup of amplification, sequencing, and variant calling steps

10 minutes

Maximum No. of libraries sequenced in a single run

384 samples

System includes secondary data-analysis software developed by company

yes (DRAGEN, BaseSpace Sequence Hub)

System includes post-sequencing data-analysis software

yes (DRAGEN)

Mutations detectable via data-analysis software

substitutions, indels, copy number changes

System can generate a variant report

yes

Types of maintenance plans available/mean time between failures

parts only, bronze, silver, gold, Dx, dedicated on-site/—

No. of field application scientists and engineers based in U.S.

>500

• Weekly maintenance required

none

• Monthly maintenance required

none

• Pre-run maintenance required

none

Distinguishing features of NGS system (supplied by company)

room temperature shipping and storage of sequencing consumables; automated onboard flow-cell denaturation, onboard cluster generation, no post-run washing; simplified data analysis with access to preconfigured DRAGEN pipelines onboard or in the cloud, minimizing the need for bioinformatics expertise

More products
in this guide

NextSeq 550Dx
NextSeq 1000; NextSeq 2000
NovaSeq 6000Dx
NovaSeq X; NovaSeq X Plus
Ion GeneStudio S5 System
Ion Torrent Genexus Integrated Sequencer; Ion Torrent Genexus Dx Integrated Sequencer