Webinars and Sponsored Roundtables — Register Now

Thursday, May 28, 2026, 1:00–2:00 PM ET
This session is designed to improve understanding and application of recent updates to synoptic pathology reporting protocols such as the latest Reporting Template for Reporting Results of Biomarker Testing of Specimens from Patients with Carcinoma of the Breast. These changes reflect evolving clinical guidelines that directly influence diagnostic accuracy and treatment selection in breast cancer care.

Webinar presenters Thaer Khoury, MD, FCAP, Chair, Pathology and Laboratory Medicine, Roswell Park Comprehensive Cancer Cente, and Colin Murphy,  CEO of mTuitive.

Moderated by: Bob McGonnagle, Publisher, CAP TODAY

Tuesday, June 9, 2026, 1:00–2:00 PM ET
In this webinar, we will examine how immune recognition after allogeneic HCT can influence leukemia relapse and disease progression. The session will highlight the clinical relevance of HLA loss of heterozygosity (LOH), approaches used for its detection, and how LOH findings may support transplant strategies, including considerations for donor selection in subsequent transplantation.

Webinar presenter Alberto Cardoso Martins Lima, PhD, Clinical consulting scientist in histocompatibility,
specializing in allogeneic hematopoietic cell transplantation (HCT) at IGEN/AFIP São Paulo and CHC/UFPR in Curitiba, Brazil

Moderated by: Bob McGonnagle, Publisher, CAP TODAY

Wednesday, June 24, 2026, 12:00–1:00 PM ET
Hear an expert discuss the expanded clinical utility of HER2 IHC scoring in metastatic breast cancer and its impact on your practice

Webinar presenter Michelle Shiller, DO, AP, CP, MGP, FACP, Baylor University Medical Center.

Moderated by: Bob McGonnagle, Publisher, CAP TODAY

Subspecialties

Interactive Product Guides

Product Spotlight

Illumina

MiSeq i100 Plus

Company

Illumina

Name of system

MiSeq i100 Plus

Email

info@illumina.com

City, State

San Diego, CA

Phone

858-202-4500  

Website

http://www.illumina.com

System application/FDA cleared or approved

research use/not required

Country where designed/Manufactured

U.S./Singapore

First year sold in U.S./First year installed in U.S.

2024/2024

System sold internationally

yes (worldwide)

Dimensions of sequencer (H × W × D)/Footprint of sequencer

25.6 × 15.8 × 17.6 in./1.9 sq. ft.

Accessory equipment supplied with sequencer at no cost

Type of computer supplied with sequencer

computer for analysis and operations combined

Analysis options provided with sequencer

onboard, cloud based

Where library preparation is performed

wet bench

Bioinformatics tools provided with sequencer

DRAGEN Bio-IT, BaseSpace Sequence Hub, Illumina Connected Analytics

Sequencer supplied with UPS (uninterruptible power supply)

no

Electrical connection required for sequencer

100–240 at VAC 50/60 Hz, 300 W, single phase

List price of entire sequencer and necessary components

$109, 900

Purchase options

purchase

Warranties offered

Training included/Total time for basic training per operator

no/2 days

Training location/Follow-up training available

at vendor office or customer site/yes (extra charge)

Maximum No. of samples amplified in a single amplification event

384 samples

Read length/Percent bases >Q30

up to 2 × 300 bp/85% (for 2 × 300 bp)

Paired-end capability/Tag lengths/Spans

yes/up to 2 × 500 bp/950 bp

Fragment/Tag lengths/Spans

yes/up to 2 × 300 bp/—

Mate pair/Tag lengths/Spans

yes/up to 2 × 150 bp/—

Single end/Tag lengths/Spans

yes/up to 1 × 300 bp/—

RNA sequencing/Tag lengths/Spans

yes/up to 2 × 300 bp/—

ChIP sequencing/Tag lengths/Spans

yes/up to 2 × 300 bp/—

Bisulfite sequencing/Tag lengths/Spans

yes/up to 2 × 300 bp/—

Maximum No. of reads or fragments sequenced per single-end run

100 million

Maximum No. of reads or fragments sequenced per paired-end run

200 million

Total No. of nucleotides (bases) sequenced per run

30 Gb

Wet lab bench time for sequencing preparation

10 minutes

Sequencing run time

~4–24 hours

Total time for generating standard gDNA library

<3.5 hours (with Illumina DNA Prep)

• Paired end

<3.5 hours (with Illumina DNA Prep)

• Fragment

<7 hours (with AmpliSeq for Illumina); <6.5 hours (withIllumina DNA Prep with Enrichment)

• Mate pair

• Single end

<1 day (with TruSeq Small RNA)

• RNA sequencing

<9 hours

• Bisulfite sequencing

• Hands-on time for paired end

<1.5 hours (with Illumina DNA Prep)

• Hands-on time for fragment

<1.5 hours (with AmpliSeq for Illumina); <2 hours (with Illumina DNA Prep with Enrichment)

• Hands-on time for mate pair

• Hands-on time for single end

<4 hours (with TruSeq Small RNA)

• Hands-on time for RNA sequencing

<3 hours

• Hands-on time for ChIP sequencing

• Hands-on time for bisulfite sequencing

Library preparation integrated in system as standard offering

no

Cost of sequencing reagents per run

$420–$1,700

Reagent tracking method

RFID

• Type of reagent information tracked

serial No., expiration date, lot and part Nos., No. of cycles

Shipping conditions for amplification/sequencing reagents

room temperature/room temperature

Storage conditions for amplification/sequencing reagents

room temperature/room temperature

Shelf life of amplification/sequencing reagents

guaranteed 3 months/guaranteed 3 months

System requires a control sample on sequencing run 

optional

• Company offers a sequencing control

yes (additional charge)

Sequencing system control software and devices to start run/for data analysis

MiSeq i100 Control Software/BaseSpace Sequence Hub, DRAGEN secondary analysis

Complete walkaway automation for amplification, sequencing, and variant calling

yes

Remote system monitoring

yes

Total time required for setup of amplification, sequencing, and variant calling steps

10 minutes

Maximum No. of libraries sequenced in a single run

384 samples

System includes secondary data-analysis software developed by company

yes (DRAGEN, BaseSpace Sequence Hub)

System includes post-sequencing data-analysis software

yes (DRAGEN)

Mutations detectable via data-analysis software

substitutions, indels, copy number changes

System can generate a variant report

yes

Types of maintenance plans available/mean time between failures

parts only, bronze, silver, gold, Dx, dedicated on-site/—

No. of field application scientists and engineers based in U.S.

>500

• Weekly maintenance required

none

• Monthly maintenance required

none

• Pre-run maintenance required

none

Distinguishing features of NGS system (supplied by company)

room temperature shipping and storage of sequencing consumables; automated onboard flow-cell denaturation, onboard cluster generation, no post-run washing; simplified data analysis with access to preconfigured DRAGEN pipelines onboard or in the cloud, minimizing the need for bioinformatics expertise

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in this guide

NextSeq 550Dx
NextSeq 1000; NextSeq 2000
NovaSeq 6000Dx
NovaSeq X; NovaSeq X Plus
Ion GeneStudio S5 System
Ion Torrent Genexus Integrated Sequencer; Ion Torrent Genexus Dx Integrated Sequencer