Webinars and Commercial Conversations — Register Now

Tuesday, November 10, 2026, 1:00 PM-2 PM ET
Join us for a session to help improve diagnostic accuracy in your practice when scoring HER2 IHC 0 with faint, incomplete membrane staining in ≤10% of tumor cells vs IHC 0 with no membrane staining detected in patients with mBC.

Webinar presenter Samuel Caughron, MD, FCAP, Chief Strategy Officer, MAWD Pathology, Medical Director of Laboratory, AdventHealth Kansas City, Medical Director of Laboratory, Labcorp, President, Member & Director, Pathology Ventures, LLC

CAP TODAY does not endorse any of the products or services named within. This program is intended for US healthcare professionals. This program is being sponsored by AstraZeneca. The speaker is being compensated for the presentation. The program is not CME accredited and may not be used for CME accreditation.

Moderated by: Bob McGonnagle, Publisher, CAP TODAY

Monday, November 16, 2026, 12:30 PM-2 PM ET
Hear experts discuss a multidisciplinary approach to oncopathology for HER2
assessments for solid tumors in the absence of a companion diagnostic.

Webinar presenters Funda Meric-Bernstam, MD, Chair, Department of Investigational Cancer Therapeutics Medical Director, Institute for Personalized Cancer Therapy, The University of Texas MD Anderson Cancer Center, Houston, Texas, and Emina E. Torlakovic, MD, PhD, College of Medicine, University of Saskatchewan, Canadian Biomarker Quality Assurance, Saskatoon, Saskatchewan, Canada, and Carol Cheung, MD, PhD, JD, FRCPC, Deputy Director, Canadian Biomarker Quality, Assurance—Programme canadien d’assurance de la qualité des biomarqueurs

CAP TODAY does not endorse any of the products or services named within. This program is being sponsored by Daiichi Sankyo, Inc. and AstraZeneca. The speaker is being compensated for the presentation. The program is not CME accredited and may not be used for CME accreditation.

Moderated by: Bob McGonnagle, Publisher, CAP TODAY

Wednesday, November 18, 2026, 12:00 PM-1 PM ET
Join leading pathology experts, Savitri Krishnamurthy, MD, and Marilyn Bui, MD, PhD, for a webinar exploring potential challenges in HER2 IHC testing for breast cancer, emerging evidence supporting digital and computational pathology as assistive tools for pathologists in HER2 IHC assessment, and practical considerations for real-world implementation and adoption.

Webinar presenters Savitri Krishnamurthy, MD, Professor of Pathology, Department of Anatomical Pathology The University of Texas MD Anderson Cancer Center, Houston, Texas, and Marilyn Bui, MD, PhD, Surgical Pathologist and Cytopathologist Member and Professor, Departments of Pathology, Machine Learning, and Translational Pathology, Scientific Director, Analytic Microscopy Core Chair, Women in Oncology Executive Board Moffitt Cancer Center, Tampa, Florida

CAP TODAY does not endorse any of the products or services named within. This program is being sponsored by Daiichi Sankyo, Inc. and AstraZeneca. The speakers are being compensated for their presentations. The program is not CME accredited and may not be used for CME credit.

Moderated by: Bob McGonnagle, Publisher, CAP TODAY

Wednesday, December 9, 2026, 12 PM-1 PM ET
Hear an expert pathologist discuss the role of HER2 IHC testing and scoring in solid tumors including endometrial, ovarian, cervical, bladder, non-small cell lung, colorectal, and biliary cancers

Webinar presenter Michelle Shiller, DO, MSPT, Baylor Sammons Cancer Center; Fulgent Genetics; Texas Cancer Interception Institute

CAP TODAY does not endorse any of the products or services named within. This program is intended for US healthcare professionals. This program is being sponsored by AstraZeneca. The speaker is being compensated for the presentation. The program is not CME accredited and may not be used for CME accreditation.

Moderated by: Bob McGonnagle, Publisher, CAP TODAY

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Product Spotlight

Thermo Fisher Scientific

Ion GeneStudio S5 System

Company

Thermo Fisher Scientific

Name of system

Ion GeneStudio S5 System

Email

customercare@thermofisher.com

City, State

Carlsbad, CA

Phone

800-955-6288  

Website

http://www.thermofisher.com/genestudio

System application/FDA cleared or approved

research use/not required

Country where designed/Manufactured

U.S./Singapore

First year sold in U.S./First year installed in U.S.

2018/2018

System sold internationally

yes (worldwide)

Dimensions of sequencer (H × W × D)/Footprint of sequencer

62.5 × 34.0 × 36.7 in./8.7 sq. ft.

Accessory equipment supplied with sequencer at no cost

—

Type of computer supplied with sequencer

operating computer

Analysis options provided with sequencer

onboard, cloud based, local server

Where library preparation is performed

accessory equipment

Bioinformatics tools provided with sequencer

Torrent Suite (optional: Ion Reporter, Oncomine Reporter)

Sequencer supplied with UPS (uninterruptible power supply)

no

Electrical connection required for sequencer

100–240 VAC at 50/60 Hz, 6.5–14.5 A

List price of entire sequencer and necessary components

—

Purchase options

purchase, trade in, lease, finance

Warranties offered

first year included with purchase; extended warranty available

Training included/Total time for basic training per operator

yes/1 day

Training location/Follow-up training available

at customer site/yes (extra charge)

Maximum No. of samples amplified in a single amplification event

384 samples (>384 samples with custom barcodes)

Read length/Percent bases >Q30

up to 600 bp/—

Paired-end capability/Tag lengths/Spans

—

Fragment/Tag lengths/Spans

yes/—/up to 600 bp

Mate pair/Tag lengths/Spans

—

Single end/Tag lengths/Spans

yes/—/up to 400 bp

RNA sequencing/Tag lengths/Spans

yes/—/up to 400 bp

ChIP sequencing/Tag lengths/Spans

—

Bisulfite sequencing/Tag lengths/Spans

yes/—/up to 400 bp

Maximum No. of reads or fragments sequenced per single-end run

2–130 million

Maximum No. of reads or fragments sequenced per paired-end run

—

Total No. of nucleotides (bases) sequenced per run

20–25 Gb (Ion 550); 10–15 Gb (Ion 540); 3–4 Gb (Ion 530); 0.6–1 Gb (Ion 520); 0.3–0.5 Gb (Ion 510 chip)

Wet lab bench time for sequencing preparation

<45 minutes

Sequencing run time

2.5–4 hours

Total time for generating standard gDNA library

—

• Paired end

—

• Fragment

4–6 hours

• Mate pair

—

• Single end

5–7 hours

• RNA sequencing

<6 hours

• Bisulfite sequencing

5.5 hours

• Hands-on time for paired end

—

• Hands-on time for fragment

1 hour

• Hands-on time for mate pair

<1 hour

• Hands-on time for single end

15 minutes 

• Hands-on time for RNA sequencing

1 hour (with Ion AmpliSeq Transcriptome)

• Hands-on time for ChIP sequencing

—

• Hands-on time for bisulfite sequencing

30 minutes

Library preparation integrated in system as standard offering

no (performed on Ion Chef)

Cost of sequencing reagents per run

—

Reagent tracking method

RFID

• Type of reagent information tracked

expiration date, lot and part Nos.

Shipping conditions for amplification/sequencing reagents

-20°C, 4°C, ambient (variable based on product)/-20°C, 4°C, ambient (variable based on product)

Storage conditions for amplification/sequencing reagents

-20°C, 4°C, ambient (variable based on product)/-20°C, 4°C, ambient (variable based on product)

Shelf life of amplification/sequencing reagents

12–36 months from manufacture date (variable based on product)/12–36 months from manufacture date (variable based on product)

System requires a control sample on sequencing run 

optional

• Company offers a sequencing control

yes (additional charge)

Sequencing system control software and devices to start run/for data analysis

Torrent Suite/Ion Reporter

Complete walkaway automation for amplification, sequencing, and variant calling

no (walkaway automation for sequencing, variant calling)

Remote system monitoring

—

Total time required for setup of amplification, sequencing, and variant calling steps

<30 minutes

Maximum No. of libraries sequenced in a single run

384 samples

System includes secondary data-analysis software developed by company

yes (Torrent Suite, Ion Reporter)

System includes post-sequencing data-analysis software

yes (Torrent Suite, Ion Reporter)

Mutations detectable via data-analysis software

substitutions, indels, copy number changes

System can generate a variant report

yes

Types of maintenance plans available/mean time between failures

AB Assurance/—

No. of field application scientists and engineers based in U.S.

450

• Weekly maintenance required

—

• Monthly maintenance required

—

• Pre-run maintenance required

—

Distinguishing features of NGS system (supplied by company)

scalable, flexible, end-to-end NGS solution from library to report with turnaround time of <24 hours and <45 minutes of hands-on time; start with as little as 1 ng of input DNA or RNA; flexible sequencing depth and sample number throughput

More products
in this guide

MiSeq i100 Plus
NextSeq 550Dx
NextSeq 1000; NextSeq 2000
NovaSeq 6000Dx
NovaSeq X; NovaSeq X Plus
Ion Torrent Genexus Integrated Sequencer; Ion Torrent Genexus Dx Integrated Sequencer