Grading, staging papillary urothelial carcinoma
July 2026—Grading of papillary urothelial carcinoma can sometimes be challenging because it requires categorizing discretely a continuous spectrum of tumors. In the view of Lara Harik, MD, discovering biomarkers that can predict progression would be an ideal solution for papillary urothelial carcinoma, especially for tumors that are difficult to grade. “Maybe the use of cell-free DNA in the near future,” she said, “could reveal which of these tumors are at risk for progression.”