Webinars and Sponsored Roundtables — Register Now

Wednesday, September 23, 2026. 12 PM-1 PM ET
Roundtable presenters Dr. David Sacks MB, ChB, FRCPath, Chairman, Steering Committee National Glycohemoglobin Standardization Program (NGSP), and Priya Sivaraman, PhD, Senior Technical Product Manager, Tosoh Bioscience.

Moderated by: Bob McGonnagle, Publisher, CAP TODAY

Thursday, September 24, 2026 11 AM-12 PM CT
This session explores the evolving role of RAS in precision oncology, from the biology of RAS mutations to the expanding landscape of targeted therapies. Through expert presentations, real-world case discussions, and interactive audience polling, participants will examine best practices for RAS biomarker testing across solid tumors, including lung, colorectal, and pancreatic cancers. The session will highlight practical considerations for tissue and liquid biopsy, strategies to address testing gaps, and the importance of multidisciplinary collaboration to ensure timely identification of patients who may benefit from RAS-targeted therapies.

Webinar presenters David Braxton, MD, Chief of Molecular Pathology Services, Hoag Family Cancer Institute & Hoag Memorial Hospital Presbyterian, and Carlos Becerra, MD, Research Director for Medical Oncology, Margaret Given Larkin Endowed Chair for Developmental Cancer Therapeutics, Hoag Memorial Hospital Presbyterian.

Moderated by: Bob McGonnagle, Publisher, CAP TODAY

Wednesday, September 30, 2026. 1 PM-1:30 PM ET
Roundtable presenters John Longshore, PhD, Head of Scientific Affairs, Global Oncology Diagnostics, AstraZeneca, and Flora Berisha, MS, Executive Director, Global Head of Diagnostic Partnering and Development, Johnson & Johnson Innovative Medicine, and Mark D. Ewalt, MD, Associate Medical Director for Laboratory Operations, Diagnostic Molecular Pathology, Molecular Diagnostics Service, Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, and Isabel Preeshagul, DO, MBS, Thoracic Medical Oncologist, Memorial Sloan Kettering Cancer Center.

Moderated by: Bob McGonnagle, Publisher, CAP TODAY

Tuesday, October 20, 2026 11 AM-12 PM ET
Hear experts review the biological and clinical significance of the HER2 expression continuum in breast tissue, providing a clearer understanding of how these variations might impact diagnosis, and discuss the emerging importance of documenting HER2-low and HER2-ultralow categories using a validated IHC assay.

Webinar presenters Keith Wharton, MD, PhD, Global Medical Affairs Leader–Pathology,
Roche Diagnostics Solutions, and Hannah Y. Wen, MD, PhD, Director, Breast Pathology Fellowship, Associate Team Leader, Breast Pathology Team, Attending Pathologist, Memorial Sloan Kettering Cancer Center.

Moderated by: Bob McGonnagle, Publisher, CAP TODAY

Subspecialties

Interactive Product Guides

Product Spotlight

Binding Site, part of Thermo Fisher Scientific

Optilite

Company

Binding Site, part of Thermo Fisher Scientific

Name of instrument

Optilite

Contact

Haley Braffett   

Email

haley.braffett@thermofisher.com

City, State

San Diego, CA

Phone

858-291-4556   

Website

http://www.thermofisher.com/bindingsite

Type of instrument

chemistry

List price/First year sold in U.S.

$111,521/2015

Targeted hospital bed size/Targeted test volume

> 100/daily: > 50; monthly: ~1,000; annual: ~12,000

Company manufactures instrument

yes

Other models in this family of analyzers

No. of units in clinical use in U.S./Outside U.S. (countries)

360/1,611 (Europe, Latin America, Asia-Pacific, Middle East)

Dimensions (H × W × D)/Instrument footprint

24.4 × 37 × 27.6 in./7.09 sq. ft.

Weight empty/Weight fully loaded

242 lbs./~260 lbs.

No. of different measured assays onboard simultaneously

36 (36 can be run and calibrated at one time)

No. of user-definable (open chemistry) channels

10

Test throughput per hour/Assay run time

120/8–23 min. (avg. 13 min.)

No. of direct ion-selective electrode channels

Detection methods

turbidimetry

Stat time until completion/specimen throughput for Ion-selective electrode

Stat time until completion/specimen throughput for Ion-selective electrode basic metabolic panel

Stat time until completion/specimen throughput for Ion-selective electrode complete metabolic panel

Typical time delay from ordering stat test until aspiration of sample

Fully automated microplate immunoassay system

Methodologies supported

Separation methodologies

Stat time until completion of a ß-hCG test

Stat time until completion of a cTn test

• Typical time delay from test order to aspiration of sample

Reagents refrigerated onboard/Reagents ready to use

yes (8°–10°C below ambient)/yes

Reagent lot tracking/Reagent inventory

yes/yes

Reagent form/Reagents barcoded

liquid chemistry (closed reagent system)/yes

Separate reagent pack for each specimen/for each test run

no/no

Walkaway capability/Walkaway duration

yes/90 min. or 54 specimens or 180 tests

Design of sample-handling system

rack

Uses washable cuvettes/Uses disposable cuvettes

no/yes (can store up to 360 cuvettes)

Min.–max. sample volume that can be aspirated at one time 

2–200 µL

Min. reaction volume/Min. specimen volume/Min. dead volume

120 µL/assay dependent/150 µL

Dedicated pediatric sample cup

yes (dead volume: 150 µL)

Primary tube sampling

yes

Accommodates most standard tube sizes/Accepts nonstandard tube sizes

yes/yes (13 × 75 mm, 12 × 75 mm)

Pierces caps on primary tubes

no

Protects against probe collision

yes

Detects clots/liquid level/short sample

yes/yes/yes

Detection or quantitation for hemolysis, icterus, lipemia, clots

detection for hemolysis, clots; icterus, lipemia not available

Dilutes patient samples onboard/Susceptibility to carryover

yes (can be programmed to perform dilutions prior to analysis)/—

Automatic rerun capability

yes

Sample volume can be diluted to rerun out-of-linear-range high results

yes

Sample volume can be concentrated to rerun out-of-linear-range low results

yes

Autocalibration/Multipoint calibration supported

no (calibrants are not stored onboard)/yes (recommended avg. frequency: per lab protocol and every new lot)

Typical calibration frequency for ISE/therapeutic drugs/drugs of abuse/general chemistries/immunoassays

Automatic programmable start/Automatic programmable shutdown

no/no

Onboard real-time QC/Onboard software capability to review QC

yes/yes

Supports multiple QC lot numbers per analyte

no

Waste management

automated collection onboard instrument

Sample barcode-reading capability/Autodiscrimination

yes (Interleaved 2 of 5, Codabar, Code 39, Code 128)/no

Lab can control analyzer from remote computer

no

Instrument can diagnose its own malfunctions

no (operator intervention required to order parts)

System malfunctions can be diagnosed via remote monitoring

no

UPS backup power supply

yes

Data-management capability/LIS or EHR systems interfaced

onboard/Epic, Clinisys, Oracle Health, SCC Soft Computer

LIS interface provided/Bidirectional interface capability

yes (additional cost)/yes (broadcast download and host query)

Modem servicing provided/Service engineer on-site response time

no/next business day

Mean time between failures

502 days (displays error codes for troubleshooting)

Average scheduled maintenance time by lab personnel

daily: 10 min.; weekly: 15 min.; monthly: 30 min.

Maintenance records kept onboard for user/vendor

some records (log)/no

Maintenance training demonstration module onboard

no

Training included with purchase/Avg. time for basic user training

yes (2 training slots)/2 days (primarily at customer site)

Advanced operator training/Extra charge for follow-up or advanced training

yes (at customer site)/$2,500

Warranty provided/Cost of annual service contract (24 h/7 d)

yes (1 year)/$12,950

Distinguishing features (supplied by company)

reduced carryover due to disposable cuvettes; dilution cascade to final result; intuitive software that includes three different antigen excess protection methods, optimized by assay

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