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Webinars and Sponsored Roundtables — Register Now

Thursday, October 29, 2026, 1 PM-2 PM ET
Hear an expert discuss the evolving role of PD-L1 testing in HNSCC and ovarian cancer.

Webinar presenter Georgios Deftereos, MD, Professor of Pathology, Associate Director of the Clinical Cancer Genomics Laboratory, Director of Molecular Cytopathology, University of California, San Francisco

CAP TODAY does not endorse any of the products or services named within. The webinar is made possible by a special educational grant from Agilent.

Moderated by: Bob McGonnagle, Publisher, CAP TODAY

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Tuesday, November 3, 2026, 1 PM-2 PM ET
Hear an expert discuss the challenges of detecting NRG1 fusions and how RNA-based testing can support more comprehensive fusion identification in clinical practice.

Webinar presenter Benjamin Weinberg, MD, Associate Professor of Medicine and Attending Physician
specializing in gastrointestinal medical oncology

CAP TODAY does not endorse any of the products or services named within. The webinar is made possible by a special educational grant from Diaceutics.

Moderated by: Bob McGonnagle, Publisher, CAP TODAY

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Tuesday, November 10, 2026, 1 PM-2 PM ET
Join us for a session to help improve diagnostic accuracy in your practice when scoring HER2 IHC 0 with faint, incomplete membrane staining in ≤10% of tumor cells vs IHC 0 with no membrane staining detected in patients with mBC.

Webinar presenter Jeffrey Gregg, MD, University of Nevada

CAP TODAY does not endorse any of the products or services named within. This program is being sponsored by Daiichi Sankyo, Inc. and AstraZeneca. The speaker is being compensated for the presentation. The program is not CME accredited and may not be used for CME accreditation.

Moderated by: Bob McGonnagle, Publisher, CAP TODAY

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Monday, November 16, 2026, 12:30 PM-2 PM ET
Hear experts discuss a multidisciplinary approach to oncopathology for HER2
assessments for solid tumors in the absence of a companion diagnostic.

Webinar presenters Funda Meric-Bernstam, MD, Chair, Department of Investigational Cancer Therapeutics Medical Director, Institute for Personalized Cancer Therapy, The University of Texas MD Anderson Cancer Center, Houston, Texas, and Emina E. Torlakovic, MD, PhD, College of Medicine, University of Saskatchewan, Canadian Biomarker Quality Assurance, Saskatoon, Saskatchewan, Canada, and Carol Cheung, MD, PhD, JD, FRCPC, Deputy Director, Canadian Biomarker Quality, Assurance—Programme canadien d’assurance de la qualité des biomarqueurs

CAP TODAY does not endorse any of the products or services named within. This program is being sponsored by Daiichi Sankyo, Inc. and AstraZeneca. The speaker is being compensated for the presentation. The program is not CME accredited and may not be used for CME accreditation.

Moderated by: Bob McGonnagle, Publisher, CAP TODAY

Register Now

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All Issues

Put It on the Board

October 2024—The two lawsuits filed by the American Clinical Laboratory Association and Association for Molecular Pathology that challenge the Food and Drug Administration’s final rule on laboratory-developed tests will be consolidated in the U.S. District Court for the Eastern District of Texas, according to a motion filed Sept. 9. During the weeks of Aug. 26 and Sept. 2, the parties to both actions conferred on how to litigate both cases “in a just, speedy, and efficient manner,” the motion says. It adds that all parties in both cases consent to the transfer of the AMP case to the Eastern District “and agree that, subject to this Court’s discretion, the two cases then should be consolidated for joint briefing and decision.”

In memoriam

October 2024—Frederick L. “Fritz” Kiechle, MD, PhD, editor of the CAP TODAY “Q&A” column from 2008 to 2024, died on July 30 at age 78. “He was a champion for clinical pathology, a champion for the laboratory. He was an innovator in clinical chemistry,” and “devoted to resident education,” says Dorothy Adcock, MD, chair of the CAP Publications Committee and former chief medical officer, Labcorp. Dr. Kiechle was an author of the CAP Publications manual So You’re Going to Collect a Blood Specimen, through its soon-to-be 16th edition. He wrote Disruptive Technologies in Clinical Medicine, which the CAP published in 2023. He was a member of the CAP Publications Committee from 1993 to this year, having served 12 of those years as an advisor. He was a member of the Archives of Pathology & Laboratory Medicine editorial board (2006–2023), member and then chair of the Patient Preparation and Specimen Handling editorial board (1993–1996), and a member of the Chemistry (2008–2013) and Special Chemistry (2006–2007) resource committees.

New Enhertu use, new HER2 complexities

September 2024—Every profession has its own news cycle. In pathology, the story arc is often a lengthy one, stretching from clinical triumph to Now what? Such is the case with expanded use of trastuzumab deruxtecan, which was granted accelerated FDA approval in late April for adult patients with unresectable or metastatic HER2-positive (IHC 3+) solid tumors who received prior systemic treatment and have no alternative treatment options. Three multicenter trials evaluated the efficacy of the drug: DESTINY-PanTumor02, DESTINY-Lung01, and DESTINY-CRC02. PanTumor02 looked at seven tumor cohorts: endometrial, cervical, ovarian, bladder, biliary tract, pancreatic, and other solid cancers (excluding breast, colorectal, gastric, and non-small cell lung cancers). The results of these trials often were striking (median duration of response for PanTumor02 was 19.4 months, for example), and physicians are now looking closely at this tumor-agnostic (also referred to as tissue-agnostic) indication.

Intraop neuropathology consultation: tips and cases

September 2024—Leomar Ballester, MD, PhD, of the University of Texas MD Anderson Cancer Center has simple advice for those called to provide an intraoperative neuropathologic consultation: review the imaging and know the entities.

Host response solutions to sepsis risk prediction

September 2024—When emergency physician Chadd Kraus, DO, DrPH, of Lehigh Valley Health Network in Allentown, Pa., sees a patient who could have sepsis, he wants to know if there’s an infection and, if so, how bad it is based on the patient’s host response, what interventions are needed, and whether the patient will need to be hospitalized.

Self-collected vaginal swabs studied for HPV tests

September 2024—In HPV primary screening, self-collected vaginal samples enable accurate clinical HPV testing, and neither extended ambient dry storage nor exposure to extreme temperatures influence HPV detection, say the authors of a study published in June.

Eyes on LDT inventory and cyberattack readiness

September 2024—The ADLM meeting in Chicago had just wrapped up when Compass Group members met online Aug. 6 with CAP TODAY publisher Bob McGonnagle. Stan Schofield, Compass Group VP and managing principal, noted Allina Health had announced in late June its definitive agreement with Quest Diagnostics for select assets of Allina’s laboratory services business, and Schofield reported plenty of M&A talk at the ADLM meeting. The group’s August discussion began there and moved to laboratory-developed tests and cybersecurity.

A trio of magic potions to protect laboratories

September 2024—A “grimoire” for laboratories—that’s what J. Mark Tuthill, MD, of Henry Ford Health was asked to talk about at the Pathology Informatics Summit in May. Once he learned what the term meant, he got to work, and his book of magic for laboratories unfolded. He did not use a large language model to create his spells because “only a wizard” can teach such things, he said, which is why he consulted his 11-year-old grandson.

Tapping into the potential of urinalysis

September 2024—Tried and true but also having untapped potential is how three industry insiders see urinalysis. Though traditional urinalysis serves its purpose well, they say, it’s easy to envision the next level. “We tend to look at urinalysis with a fairly myopic view of counting particles and doing a dipstick,” says Jason Anderson, MPH, MT(ASCP), senior product manager for urinalysis solutions, Sysmex America. “So what becomes the definition of urinalysis in the future?” he asks. “When we look at blood, it isn’t plasma analysis, it isn’t serum analysis. It’s specific disease conditions, disciplines that use that fluid type. So I see urinalysis becoming a broader field in a sense that there has been a lack of research in urinalysis in general for some time and there’s huge capacity in a urine sample and an unmet need for better biomarkers.” This need, he says, spans the spectrum of diseases, not just renal diseases. “And those biomarkers, those metabolites, that are potentially useful in diagnosing various conditions can be found in urine.”

‘First of its kind’ update for cancer surveillance standards

September 2024—New cancer surveillance standards for tumor site, histology, and behavior code combinations and associated terms rolled out this year, after pathologists reviewed the combinations in an all-new effort. It’s an initiative known as Cancer PathCHART, short for Cancer Pathology Coding Histology and Registration Terminology, led by the National Cancer Institute with the support of 10 collaborating organizations, among them the CAP and the World Health Organization. “Nobody but the NCI could’ve done this. It’s been a great project,” says Kay Washington, MD, PhD, professor of pathology at Vanderbilt University Medical Center and a past member of the CAP Cancer Committee and American Joint Committee on Cancer.

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