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This presentation will explore the value of in-house CGP, offer insights into the benefits and drawbacks of incorporation, and provide information about important practical factors when considering in-house implementation of CGP.

Webinar presenter Allison M. Cushman-Vokoun, MD, PhD, FCAP, Medical Director, Molecular Diagnostics and Personalized Medicine Laboratory, Director, Division of Diagnostic Molecular Pathology and Human Genetics, Henry F. Krous Professor of Pathology, University of Nebraska Medical Center

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Tuesday, October 20, 2026 11 AM-12 PM ET
Hear experts review the biological and clinical significance of the HER2 expression continuum in breast tissue, providing a clearer understanding of how these variations might impact diagnosis, and discuss the emerging importance of documenting HER2-low and HER2-ultralow categories using a validated IHC assay.

Webinar presenters Keith Wharton, MD, PhD, Global Medical Affairs Leader–Pathology, Roche Diagnostics Solutions, and Hannah Y. Wen, MD, PhD, Director, Breast Pathology Fellowship, Associate Team Leader, Breast Pathology Team, Attending Pathologist, Memorial Sloan Kettering Cancer Center

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Tuesday, November 3, 2026 1 PM-2 PM ET
Hear an expert discuss the challenges of detecting NRG1 fusions and how RNA-based testing can support more comprehensive fusion identification in clinical practice.

Webinar presenter Benjamin Weinberg, MD, Associate Professor of Medicine and Attending Physician
specializing in gastrointestinal medical oncology

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Moderated by: Bob McGonnagle, Publisher, CAP TODAY

Subspecialties

Interactive Product Guides

Product Spotlight

Thermo Fisher Scientific

Phadia 250 Laboratory System

Company

Thermo Fisher Scientific

Name of instrument

Phadia 250 Laboratory System

Contact

John Karr    

Email

john.karr@thermofisher.com

City, State

Portage, MI

Phone

800-346-4363   

Website

http://www.thermofisher.com/phadia

Type of instrument

immunoassay

List price/First year sold in U.S.

—/2004

Targeted hospital bed size/Targeted test volume

—/annual: > 20,000–95,000

Company manufactures instrument

no (manufactured by Hitachi)

Other models in this family of analyzers

Phadia 1000, Phadia 2500, Phadia 5000 Laboratory Systems

No. of units in clinical use in U.S./Outside U.S. (countries)

> 260/> 2,135

Dimensions (H × W × D)/Instrument footprint

73 × 50 × 30 in. plus 26-in. wide computer stand/54 sq. ft.

Weight empty/Weight fully loaded

485 lbs./—

No. of different measured assays onboard simultaneously

6 (6 can be run and calibrated at one time)

No. of user-definable (open chemistry) channels

0

Test throughput per hour/Assay run time

60 tests/100 min.

No. of direct ion-selective electrode channels

—

Detection methods

—

Stat time until completion/specimen throughput for Ion-selective electrode

—

Stat time until completion/specimen throughput for Ion-selective electrode basic metabolic panel

—

Stat time until completion/specimen throughput for Ion-selective electrode complete metabolic panel

—

Typical time delay from ordering stat test until aspiration of sample

—

Fully automated microplate immunoassay system

no

Methodologies supported

fluoroenzyme immunoassay

Separation methodologies

fiber matrix filter, coated microwell

Stat time until completion of a ß-hCG test

—

Stat time until completion of a cTn test

—

• Typical time delay from test order to aspiration of sample

—

Reagents refrigerated onboard/Reagents ready to use

yes (2°–8°C for conjugates, ImmunoCAP, EliA wells; others at room temperature)/variable; reagent specific

Reagent lot tracking/Reagent inventory

yes/yes

Reagent form/Reagents barcoded

liquid chemistry (closed reagent system)/yes

Separate reagent pack for each specimen/for each test run

no/no

Walkaway capability/Walkaway duration

yes/100 min.

Design of sample-handling system

rack

Uses washable cuvettes/Uses disposable cuvettes

no/no

Min.–max. sample volume that can be aspirated at one time 

9–40 μL 

Min. reaction volume/Min. specimen volume/Min. dead volume

40 μL (ImmunoCAP), 9 μL (EliA)/—/150 μL

Dedicated pediatric sample cup

no

Primary tube sampling

yes

Accommodates most standard tube sizes/Accepts nonstandard tube sizes

yes/—

Pierces caps on primary tubes

no

Protects against probe collision

yes

Detects clots/liquid level/short sample

yes/yes/yes

Detection or quantitation for hemolysis, icterus, lipemia, clots

detection for clots; hemolysis, icterus, lipemia not available

Dilutes patient samples onboard/Susceptibility to carryover

yes/—

Automatic rerun capability

no

Sample volume can be diluted to rerun out-of-linear-range high results

yes

Sample volume can be concentrated to rerun out-of-linear-range low results

no

Autocalibration/Multipoint calibration supported

yes (calibrants are stored onboard)/yes (recommended avg. frequency: 28 days)

Typical calibration frequency for ISE/therapeutic drugs/drugs of abuse/general chemistries/immunoassays

—/—/—/—/28 days

Automatic programmable start/Automatic programmable shutdown

yes/yes

Onboard real-time QC/Onboard software capability to review QC

yes/yes

Supports multiple QC lot numbers per analyte

yes

Waste management

automated collection onboard instrument or direct to drain

Sample barcode-reading capability/Autodiscrimination

yes (Interleaved 2 of 5, Codabar, Code 39, Code 128, Code 93, EAN-8, Industrial 2 of 5, COOP 2 of 5)/no

Lab can control analyzer from remote computer

no

Instrument can diagnose its own malfunctions

yes (operator intervention required to order parts)

System malfunctions can be diagnosed via remote monitoring

yes

UPS backup power supply

yes

Data-management capability/LIS or EHR systems interfaced

onboard/Antek, Oracle Health, Epic, GE TriplerG, McKesson, Meditech, NetLims, more

LIS interface provided/Bidirectional interface capability

—/yes (broadcast download and host query)

Modem servicing provided/Service engineer on-site response time

no/24 business hrs.

Mean time between failures

— (displays error codes for troubleshooting)

Average scheduled maintenance time by lab personnel

daily: 5 min.; weekly: 10 min.; monthly: 3 hrs.

Maintenance records kept onboard for user/vendor

some records (date of instrument maintenance)/no

Maintenance training demonstration module onboard

no

Training included with purchase/Avg. time for basic user training

yes (2 training slots)/4 days (vendor site preferred, at customer site on request)

Advanced operator training/Extra charge for follow-up or advanced training

yes (at vendor site)/—

Warranty provided/Cost of annual service contract (24 h/7 d)

yes (1 year)/—

Distinguishing features (supplied by company)

collection of high-quality, clinically relevant autoimmune disease tests with the ability to run allergy and autoimmune tests in the same run; broad specific IgE whole allergen and allergen component menu; master isotype calibration curves

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