Cytopathology in Focus: Guideline on lab workup of lymphoma in adults

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Given that many lymph nodes of indeterminate nature are subsequently found to be reactive, it is not practical to surgically excise every enlarged node. Core needle biopsies can be difficult to obtain from small or superficially located lymph nodes. Thus, the FNA procedure remains a powerful triage method for lymph nodes, especially if lymphoma is not highly suspected.

1. 1. Kroft SH, Sever CE, Bagg A, et al. Laboratory workup of lymphoma in adults. Am J Clin Pathol. 2021;155(1):12–37.
   2. Davey DD. Impact of laboratory work-up of lymphoma guidelines on cytopathology practices. J Am Soc Cytopathol. 2020:S2213-2945(20)30329-X. doi:10.1016/j.jasc.2020.12.001

Dr. VandenBussche, a member of the CAP Cytopathology Committee, is associate professor of pathology and oncology, Johns Hopkins University School of Medicine, Baltimore, Md.