CAP TODAY Pathology/Laboratory Medicine/Laboratory Management
Biotin pharmacokinetic study results
In Anne Paxton’s September 2016 article, “Beauty fad’s ugly downside: test interference,” I stated a commitment from Roche to reduce possible interferences, including biotin, and provide clear test labeling to ensure that physicians and laboratories can mitigate risk. Since that time, we have published a study of biotin pharmacokinetics that provides clarity and context on the topic of biotin (doi.org/10.4155/ipk-2017-0013).
Our pharmacokinetic study (n=54) confirmed how biotin is metabolized, which provides useful guidance to laboratories regarding biotin doses and washout periods. Topline findings are:
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