Q&A column, 6/16

Create PDF

1. Clinical Laboratory and Standards Institute. One-Stage Prothrombin Time (PT) Test and Activated Partial Thromboplastin Time (APTT) Test; Approved Guideline—Second Edition (H47-A2). May 30, 2008.
2. Ledford-Kraemer M. All mixed up about mixing studies. Clotting Times: The Official Newsletter of CLOT-ED. 2004;3(4):1–11.
3. Rodgers GM, Lehman CM. Hemostasis screening assays. In: Bennett ST, Lehman CM, Rodgers GM, eds. Laboratory Hemostasis: A Practical Guide for Pathologists. 2nd ed. Cham, Switzerland: Springer International Publishing; 2015:74.
4. Lipshitz J, Chelliah T, Aledort L. A case of factor V inhibitor with complete correction of the PT and aPTT upon mixing. Am J Hematol. 2012;87(3):313–315.
5. Ashizawa M, Kimura S, Wada H, et al. Acquired factor V inhibitor associated with life-threatening bleeding and a mixing test result that indicated coagulation factor deficiency. Hematology. 2013;18(5):300–304.
6. Franchini M, Lippi G. Acquired factor V inhibitors: a systematic review. J Thromb Thrombolysis. 2011;31(4):449–457.
7. Moser KA, Adcock Funk DM. Pitfalls in special coagulation testing: three illustrative case studies. Int J Lab Hematol. 2013;35(3):334–338.

Karen Moser, MD, Assistant Professor, Department of Pathology, Saint Louis (Mo.) University, School of Medicine
Member, CAP Coagulation, Resource Committee
[hr]

Dr. Kiechle is medical director of clini­cal pathology, Memorial Healthcare, Hollywood, Fla. Use the reader service card to submit your inquiries, or address them to Sherrie Rice, CAP TODAY, 325 Wau­ke­gan Road, Northfield, IL 60093; srice@cap.org. Those questions that are of general interest will be answered.