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Traumatic brain injury biomarkers

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Point-of-care TBI assays can be useful in sports, the military, ambulances, or the emergency room, Dr. Datta noted. One study reported that GFAP, measured on a POC platform prototype assay, “has high discriminative ability to predict intracranial abnormalities on CT scan in patients with TBI across the full injury spectrum of GCS 3–15 through 24 hours post-injury,” and outperforms S100B (Okonkwo DO, et al. J Neurotrauma. 2020;37[23]:2460–2467).

—Amy Carpenter Aquino

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