AMP case report: Use of MYD88 sequencing to confirm diagnosis of PIOL in a case with limited sample availability

Answers are online at www.amp.org/casereports and will be published next month in CAP TODAY.

1.   Which of the following is false?
a. Primary intraocular lymphoma is a distinctly different clinical entity from primary central nervous system lymphoma.
b. A combination of different diagnostic tools is usually required to clinch the diagnosis of primary intraocular lymphoma.
c. The detection of monoclonal rearrangements of the immunoglobulin heavy chain gene supports the diagnosis of primary intraocular lymphoma.
d. As little as 500 μL of sample is required for pyrosequencing and detection of the MYD88 gene.

2.   All of the following are common presenting symptoms of primary intraocular lymphoma except:
a. Floaters
b. Diplopia
c. Decreased visual acuity
d. Blurring of vision

3.    Which of the following commonly masquerades as primary intraocular lymphoma?
a. Tuberculosis
b. Syphillis
c. Sarcoidosis
d. All of the above

1.   Which of the following is false?
a. Primary intraocular lymphoma is a distinctly different clinical entity from primary central nervous system lymphoma.
b. A combination of different diagnostic tools is usually required to clinch the diagnosis of primary intraocular lymphoma.
c. The detection of monoclonal rearrangements of the immunoglobulin heavy chain gene supports the diagnosis of primary intraocular lymphoma.
d. As little as 500 μL of sample is required for pyrosequencing and detection of the MYD88 gene.

2.   All of the following are common presenting symptoms of primary intraocular lymphoma except:
a. Floaters
b. Diplopia
c. Decreased visual acuity
d. Blurring of vision

3.    Which of the following commonly masquerades as primary intraocular lymphoma?
a. Tuberculosis
b. Syphillis
c. Sarcoidosis
d. All of the above