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What is the most specific serologic test for diagnosing IgG4-related disease?

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Perugino CA, Stone JH. IgG4-related disease: an update on pathophysiology and implications for clinical care. Nat Rev Rheumatol. 2020;16(12):702–714.

Umehara H, Okazaki K, Masaki Y, et al. Comprehensive diagnostic criteria for IgG4-related disease (IgG4-RD), 2011. Mod Rheumatol. 2012;22(1):21–30.

Wallace ZS, Naden RP, Chari S, et al. The 2019 American College of Rheumatology/European League Against Rheumatism classification criteria for IgG4-related disease. Ann Rheum Dis. 2020;79(1):77–87.

Danyel H. Tacker, PhD, D(ABCC)
Professor of Pathology
Medical Director, Clinical Chemistry and Mass Spectrometry Laboratories
West Virginia University Medicine
Morgantown, WV
Member, CAP Diagnostic Immunology and Flow Cytometry Committee

Anne E. Tebo, PhD, D(ABMLI)
Professor of Pathology
Senior Associate Consultant, Antibody Immunology Laboratory
Mayo Clinic College of Medicine and Science
Rochester, Minn.
AMLI Liaison, CAP Diagnostic Immunology and Flow Cytometry Committee

 

Editor: Frederick L. Kiechle, MD, PhD
Published: February 2023

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